“…11 In the last two decades, some analytical methods have been developed for the determination of Trp. [12][13][14][15][16] Because the majority of these methods are mostly based on high performance liquid chromatography (HPLC), uorometry, capillary electrophoresis (CE) and chemiluminescence techniques and are associated with some drawbacks, such as laborious, time consuming and costly procedures, [17][18][19][20][21][22][23][24] the development of fast, selective and cost-effective tools such as sensors/biosensors appears to be more in favor of basic and clinical studies. Biosensors represent simplicity, low expense, and possibility of miniaturization.…”