A Single Pre Operative Dose of Sub Mucosal Dexamethasone is Effective in Improving Post Operative Quality of Life in the Surgical Management of Impacted Third Molars: A Comparative Randomised Prospective Study

Abstract

Objective The aim of the study was to observe and compare the effects of dexamethasone on pain, swelling and trismus administered as one dose preoperatively sub mucosal (study group 2) versus intramuscular injection (study group 1) keeping control as those who received no dose of steroid in the management of third molar surgery. Materials and methods The group 2 (20 patients) is the study group in which all the patients had single dose of preoperative sub mucosal dexamethasone of 4 mg/2 ml. The group 1 patients (20 patients) received single dose of preoperative intra muscular dexamethasone of 4 mg/2 ml. The control group (20 patients) did not receive steroid in any form. The post operative pain, swelling and trismus were assessed for all the groups. Results The submucosal dexamethasone group showed marked improvement in the mouth opening in the follow ups than the intra muscular dexamethasone group. In those five cases of bilateral impaction, in study groups 1 and 2, the mouth opening was very much significant when sub mucosal dexamethasone was given. ConclusionThe pre operative use of submucosal dexamethasone effectively reduces the post operative pain, swelling and trismus showing statistically significant results. The number of post operative use of analgesic tablets taken by the patients in the study group 2 were less compared to the study group 1 and the control group showing clinically significant results.

Development and In Vitro Evaluation of Lyotropic Liquid Crystals for the Controlled Release of Dexamethasone

“…However, those limitations can be overcome through various drug formulation strategies. New topical formulations are also necessary for wound healing, and DXM has been tested as a drug model [ 3 , 4 , 5 ]. In addition, DXM has been used in scaffolds with controlled pore structures for osteogenic differentiation of mesenchymal stem cells; research on new drug delivery systems for the controlled release of DXM is necessary [ 6 ].…”

Effectiveness of Low Level Laser Therapy (LLLT) and Dexamethasone Phonophoresis in Minimizing Postoperative Swelling Versus Trismus following Surgical Removal of Mandibular Impacted Third Molar: A Clinical Comparative Study

“…In another study aiming to compare the effects of dexamethasone on pain, swelling and trismus administered as one dose preoperatively sub mucosal versus intramuscular injection. The submucosal dexamethasone group showed marked improvement in the mouth opening in the follow ups than the intra-muscular dexamethasone group (20,21) . Other studies were concerning reduction of postoperative pain and swelling; indicated that both ultrasound and phonophoresis of dexamethasone are effective methods in pain relief and improving function (22,23)…”

O Uso Dos Antibióticos Na Remoção Dos Terceiros Molares: Revisão De Literatura.

“…Em alguns casos, a extração destes dentes se faz necessária. A remoção dos terceiros molares é uma das cirurgias mais frequentes realizadas pelos cirurgiões-dentistas (CDs) e especialistas em cirurgia bucomaxilofacial a nível ambulatorial podendo estar associado ao aparecimento de diversas alterações relacionadas ao procedimento tais como: sintomatologia dolorosa, edema, equimose, trismo e comprometimento de estruturas importantes (MAJID, 2011;NEGREIROS et al, 2012;RALDI et al, 2019;SARAVANAN et al, 2016). Assim, embora bastante comum, a extração pode ocasionar alguns traumas, sendo necessário um período de recuperação para que os pacientes possam voltar ao estilo de vida habitual após o procedimento (IBIKUNLE; ADEYEMO, 2016;RALDI et al, 2019;SARAVANAN et al, 2016).…”