A new practical reconfigurable structure for a multi-band power amplifier (PA) is proposed for UMTS handset applications. The proposed reconfigurable output matching network can reconfigure the output power as well as the frequency. It consists of a path-selection network, a powerreconfigurable network, and a frequency-reconfigurable network. To demonstrate the performance of the proposed structure, a 5 mm × 5 mm prototype reconfigurable PA module is developed for UMTS high-frequency band application. The fabricated PA module can cover any two bands out of three popular highfrequency UMTS bands. The fabricated amplifier module showed adjacent channel leakage ratios (ACLRs) better than -38 dBc up to the rated linear power and power-added efficiencies (PAEs) of higher than 38% at 28 dBm over all high-frequency UMTS bands. Efficiency degradation was limited to 2-3% compared to the single-band PA. Measured RF performance of the reconfigurable PA validates the usefulness of the proposed reconfigurable structure for multi-band UMTS applications.