A Single Dose of Propofol at the End of Surgery for the Prevention of Emergence Agitation in Children Undergoing Strabismus Surgery during Sevoflurane Anesthesia

Abstract

In children undergoing strabismus surgery, 1 mg/kg propofol at the end of surgery after discontinuation of sevoflurane decreases the incidence of agitation and improves parents' satisfaction without delaying discharge from the postanesthesia care unit.

Use of Laryngeal Mask Airway and Its Removal in a Deeply Anaesthetized State Reduces Emergence Agitation after Sevoflurane Anaesthesia in Children

“…Various strategies have been attempted to reduce the incidence of emergence agitation associated with sevoflurane anaesthesia in children, including the use of non-steroidal anti-inflammatory drugs, 6 propofol, 10 and switching inhaled anaesthetics after induction. 21 No strategy has gained widespread acceptance, and preventing or managing emergence agitation with analgesics and sedatives can delay recovery and discharge from the PACU.…”

The agitated child in recovery

“…4 Propofol, either by continuous infusion or as a bolus (1 mg/kg) just before the end of surgery, showed a protective effect against sevoflurane-induced ED. 14,15 An induction dose only had no effect. 8 Although ketamine has been used to reduce ED, ketamine itself can result in ED.…”

A comparison of single dose dexmedetomidine with propofol for the prevention of emergence delirium after desflurane anaesthesia in children

“…The incidence of ED varies between 20% and 80% depending on the scoring system used [3,5,6]. Different drugs, including analgesics [7,8], benzodiazepines [9], a 2 -adrenergic receptor agonists [10] and propofol [11] have been used, with varying success.…”

“…Propofol is commonly used for conscious sedation and induction/maintenance of general anaesthesia. Several studies evaluating the effectiveness of these agents separately in reducing ED following sevoflurane anaesthesia have shown positive results [2,[11][12][13][14]. However, Bong et al recently reported that there was no significant decrease in the incidence of ED with either of these drugs in children receiving general anaesthesia with sevoflurane for magnetic resonance imaging (MRI) [15].…”