A single bolus dose of esmolol in the prevention of intubation-induced tachycardia and hypertension in an ambulatory surgery unit

Parnass, Samuel M.; Rothenberg, David M.; Kerchberger, John P.; Ivankovich, Anthony D.

doi:10.1016/0952-8180(90)90102-9

Cited by 46 publications

(26 citation statements)

References 11 publications

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“…Changes in cerebral and systemic haemodynamics with 1.5% halothane were smaller than those seen in adults after induction with thiopental together with lidocaine or fentanyl [14]. With 2.5% halothane the suppression of the haemodynamic changes was better than with other anaesthetic protocols in adults [13,14,24,30]. A decrease in blood pressure with 2.5% halothane was not observed in this study but in other instances (Bode, submitted).…”

Section: Discussioncontrasting

confidence: 66%

“…The changes in blood pressure and heart rate in our study are similar to or lower than those observed in adults following tracheal intubation [14,24]. Since we did not record intra-arterial blood pressure continuously, we might have missed brief changes in blood pressure.…”

Section: Discussionsupporting

confidence: 58%

“…Reflex cardiovascular responses to laryngoscopy and tracheal intubation cause increases in blood pressure of 40%-50% and in heart rate of 30%-40% in adults [14,24]. A similar blood pressure increase was found in preterm infants, whereas heart rate and transcutaneous oxygen tension decreased [22].…”

Section: Discussionsupporting

confidence: 58%

“…Various drugs like local anaesthetics, beta-and alphaadrenergic antagonists, analgesics and calcium antagonists reduce the cardiovascular reflexes caused by laryngoscopy and tracheal intubation [4,[14][15][16][24][25][26]. They may also suppress the concommitant alterations of cerebral haemodynamics.…”

Section: Discussionmentioning

confidence: 99%

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Effects of laryngoscopy and tracheal intubation on cerebral and systemic haemodynamics in children under different protocols of anaesthesia

1993

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The effects of laryngoscopy and tracheal intubation on cerebral and systemic haemodynamics were studied in 30 children. The objective was to identify conditions in which the alterations of cerebral and systemic haemodynamics were minimal. The children were intubated after muscular relaxation and following 10 min of mechanical ventilation with end-tidal halothane concentrations of 1.5%, 2.0% and 2.5%, respectively. With 1.5%, 2.0% and 2.5% end-tidal halothane, the mean flow velocity increased by 26%, 19% and 5%, the mean blood pressure by 14%, 10% and 1%, and the heart rate by 26%, 8% and 5% respectively after intubation. Adverse effects of laryngoscopy and tracheal intubation on cerebral haemodynamics in children can be avoided by adequate anaesthetic protocols.

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Section: Discussioncontrasting

confidence: 66%

Section: Discussionsupporting

confidence: 58%

Section: Discussionsupporting

confidence: 58%

Section: Discussionmentioning

confidence: 99%

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Effects of laryngoscopy and tracheal intubation on cerebral and systemic haemodynamics in children under different protocols of anaesthesia

1993

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“…esmolol, is found to be more effective in controlling the increase in heart rate than the rise in blood pressure. 19 We, therefore, designed this study to compare the safety and effectiveness of the standard IV bolus doses of lidocaine and esmolol to blunt the hemodynamic response to laryngoscopy and tracheal intubation.…”

Section: Jssnmentioning

confidence: 99%

Comparative effects of lidocaine and esmolol in attenuating the hemodynamic response to laryngoscopy and intubation

Koju

Dongol

2017

J. Soc. Surg. Nepal

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Introduction: Transient hemodynamic instability is an inevitable outcome of laryngoscopy and intubation which can have serious effects in patients with COPD, heart disease and hypertension. Hemodynamic stability is one of the main goals of the anesthesiologist. This study was performed to compare the safety and effectiveness of lidocaine and esmolol in comparison to placebo-control group, in modifying the hemodynamic response to laryngoscopy and intubation.

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Esmolol — just another beta blocker?

Hall

1992

Can J Anaesth

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A single bolus dose of esmolol in the prevention of intubation-induced tachycardia and hypertension in an ambulatory surgery unit

Cited by 46 publications

References 11 publications

Effects of laryngoscopy and tracheal intubation on cerebral and systemic haemodynamics in children under different protocols of anaesthesia

Effects of laryngoscopy and tracheal intubation on cerebral and systemic haemodynamics in children under different protocols of anaesthesia

Comparative effects of lidocaine and esmolol in attenuating the hemodynamic response to laryngoscopy and intubation

Esmolol — just another beta blocker?

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