A Simplified Single Pump Circuit for Cardiac Bypass with Autogenous Oxygenation

Abstract

A simplified extracorporeal circulation (ECC) assemblage with autogenous oxygenation (AO) using a single centrifugal pump was tested in dogs. The transpulmonary gradient was obtained by increasing pressure in the right atrium through volume expansion and decreasing it in the left atrium by collecting the blood from the pulmonary veins in a reservoir placed below the level of the animal, generating a siphon effect. This arrangement dispenses with a right side pump. The heart was electrically fibrillated after perfusion was started and defibrillated at the end of the bypass. This ECC circuit allowed the maintenance of adequate hemodynamic and blood gas parameters during the bypass. The operating field and the mobility of the heart were equivalent to that of conventional cardiopulmonary bypass (CPB). We conclude that the use of a single centrifugal pump simplifies the autogenous oxygenation approach, making it a practical choice for the coronary artery bypass graft (CABG) procedure.

A new rotary blood pump for versatile extracorporeal circulation: the DeltaStream™

“…8 Marques et al even further investigated the method in animal experiments in the late 1990s with a single pump circuit. 9 Dobell and Bailey recorded the work of Charles Drew, who strongly believed in the deleterious effects of artificial oxygenation and combined techniques of lung perfusion with deep hypothermic circulatory arrest, and also performed early clinical cases using extracorporeal circulation without an oxygenator. 10 This was later called the`Drew Technique' and performed by its inventor from the late 1950s until his retirement in 1981.…”