A simple spectrophotometric method for estimation of plasma angiotensin I converting enzyme activity

Increased Serum Angiotensin-Converting Enzyme in End-Stage Renal Disease

“…It may be seen that in the patient group as a whole SACE [6,7] was significantly (t = 3.0898; p < 0.005) elevated as compared to normal controls. This is consistent with the findings of Silverstein et al [1] and earlier results of Patel and Ansari [2], Our group of 34 hemodialysis patients had been espe cially selected to comprise 20 patients with consistent hypotension (predialysis systolic blood pressure value consistently < 100 mm Hg).…”

1. Angiotensin converting enzyme

“…Several variations of this method have been reported in the literature [49,[65][66][67][68], of which some are interfered by hemoglobin and/ or bilirubin [69]. Other substrates used include p-hydroxyhippuryl-L-histidyl-L-leucine [70,71] and hippuryl-glycyl-glycine [72,73]. FAPGG was found to be the most suitable among several furanacryloyl blocked tripeptides tested, and therefore is most used in modern assays [74].…”

Angiotensin-I-Converting-Enzyme-Aktivit�t im Plasma nach Hemmung der Prostaglandinsynthese

“…[3] bestimmt. Vor und am Ende der Einnahmeperiode sowie 3 Tage nach der letzten Indomethacingabe wurde in einer heparinisierten, ven6sen Blutprobe (10 ml) die Aktivit/it des Angiotensin-I-converting-enzyme im Plasma nach der Methode yon Filipovic u. Mitarb.…”