Angiotensin-I-Converting-Enzyme-Aktivit�t im Plasma nach Hemmung der Prostaglandinsynthese

Abstract

In 18 normal human volunteers plasma angiotensin-I-converting-enzyme (ACE) activity was measured before and after inhibition of prostaglandin synthesis by indomethacin. ACE activity did not change significantly after treatment. It is concluded that renin is probably the only component of the renin angiotensin system, which is influenced by prostaglandins.

Increased Serum Angiotensin-Converting Enzyme in End-Stage Renal Disease

“…It may be seen that in the patient group as a whole SACE [6,7] was significantly (t = 3.0898; p < 0.005) elevated as compared to normal controls. This is consistent with the findings of Silverstein et al [1] and earlier results of Patel and Ansari [2], Our group of 34 hemodialysis patients had been espe cially selected to comprise 20 patients with consistent hypotension (predialysis systolic blood pressure value consistently < 100 mm Hg).…”