A simple one-step electrochemical deposition of bioinspired nanocomposite for the non-enzymatic detection of dopamine

Abstract

A simple and cost-effective electrochemical synthesis of carbon-based nanomaterials for electrochemical biosensor is of great challenge these days. Our study describes a single-step electrochemical deposition strategy to prepare a nanocomposite of electrochemically reduced graphene oxide (ErGO), multi-walled carbon nanotubes (MWCNTs), and polypyrrole (PPy) in an aqueous solution of pH 7.0 for dopamine (DA) detection. The ErGO/MWCNTs/PPy nanocomposites show enhanced electrochemical performance due to the strong π–π* stacking interactions among ErGO, MWCNTs, and PPy. The efficient interaction of the nanocomposites is confirmed by evaluating its physical and electrochemical characteristics using field-emission scanning electron microscopy, Raman spectroscopy, electrochemical impedance spectroscopy, cyclic voltammetry, and amperometry. The deposited nanocomposites are highly stable on the substrates and possess high surface areas, which is vital to improve the sensitivity and selectivity for DA detection. The controlled deposition of the ErGO/MWCNTs/PPy nanocomposites can provide enhanced electrochemical detection of DA. The sensor demonstrates a short time response within 2 s and is a highly sensitive approach for DA detection with a dynamic linear range of 25–1000 nM (R2 = 0.999). The detection limit is estimated to be 2.3 nM, and the sensor sensitivity is calculated to be 8.96 μA μM−1 cm−2, with no distinct responses observed for other biological molecules.

Chronoampermetric detection of enzymatic glucose sensor based on doped polyindole/MWCNT composites modified onto screen-printed carbon electrode as portable sensing device for diabetes

“…The clear redox peaks with the enhanced current response of the 1.5%MWCNT-dPIn and 2.0%MWCNT-dPIn can be related to the increase in electrical conductivity of the composites and fast electron transfer. 54,55…”

“…The clear redox peaks with the enhanced current response of the 1.5%MWCNT-dPIn and 2.0%MWCNT-dPIn can be related to the increase in electrical conductivity of the composites and fast electron transfer. 54,55 The cyclic voltammograms of CHI-GOx immobilized on various APTES modied on MWCNTs-dPIn electrodes are shown in Fig. S6.…”

Designing New Material Based on Functionalized Multi-Walled Carbon Nanotubes and Cu(OH)2–Cu2O/Polypyrrole Catalyst for Ethanol Oxidation in Alkaline Medium

“…The bare CPE has a small redox peak and a high peak-to-peak potential separation (ΔEp) of about 340 mV due to the relatively small surface area and low electron transfer (Salih et al, 2017a;Salih et al, 2017b;Salih et al, 2018;Oularbi et al, 2020). For the Cu(OH) 2 -Cu 2 O/PPy/CPE, the current densities of the anodic and cathodic peaks increased and the ΔEp value was reduced to 160 mV compared to those of the improvement of the electronic transfer at the electrode surface as suggested by many authors (Fard et al, 2017;Kathiresan et al, 2021). The electrochemical parameters of the different electrodes recorded from the CV curves (Figure 5A) are reported in Table 1.…”

Reduced Graphene Oxide Based Electrochemical Nonenzymatic Human Serum Glucose Sensor

“…A decrease in I D /I G ratio suggests an increase in the size of sp 2 domains and ordered crystal structure of rGO. [33] Presence of 2D band at 2697 cm -1 strongly supports reduction of GO. [34] 3.6 XPS analysis C1s spectra of rGO shows the reduction of GO using aqueous lemon peel extract and validates the removal of O2 functional group (Fig.…”