A simple but effective near-infrared ratiometric fluorescent probe for hydrazine and its application in bioimaging

Dai, Xi; Wang, Zhaoyang; Du, Zhi-Fang; Jiang, Miao; Zhao, Bao‐Xiang

doi:10.1016/j.snb.2016.03.159

Cited by 62 publications

(16 citation statements)

References 56 publications

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“…In a mixture of DMSO and HEPES (6:4, v / v , pH 7.4), hydrazine can selectively decompose the probe into a non‐emissive 4‐hydrazine‐1,8‐naphthalimide and a highly fluorescent coumarin derivative, thus achieving a turn‐on fluorescent response to hydrazine. Zhao and co‐workers developed a NIR ratiometric fluorescent hydrazine probe ( 86 ) based on a hybrid fluorophore of coumarin and benzopyrylium (Figure ) . The probe displays an emission band at 694 nm and an absorption peak at 645 nm.…”

Section: Probes Based On Other Recognition Moietiesmentioning

confidence: 99%

Recent progress in the development of fluorescent probes for hydrazine

et al. 2018

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Hydrazine (N H ) is an important and commonly used chemical reagent for the preparation of textile dyes, pharmaceuticals, pesticides and so on. Despite its widespread industrial applications, hydrazine is highly toxic and exposure to this chemical can cause many symptoms and severe damage to the liver, kidneys, and central nervous system. As a consequence, many efforts have been devoted to the development of fluorescent probes for the selective sensing and/or imaging of N H . Although great efforts have been devoted in this area, the large number of important recent studies have not yet been systematically discussed in a review format so far. In this review, we have summarized the recently reported fluorescent N H probes, which are classified into several categories on the basis of the recognition moieties. Moreover, the sensing mechanism and probes designing strategy are also comprehensively discussed on aspects of the unique chemical characteristics of N H and the structures and spectral properties of fluorophores.

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Section: Probes Based On Other Recognition Moietiesmentioning

confidence: 99%

Recent progress in the development of fluorescent probes for hydrazine

et al. 2018

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“…During the last few decades, a series of turn-on probes were applied to detect N 2 H 4 in living biosamples (Cui et al, 2014 ; Goswami et al, 2014a , b , 2015 ; Liu et al, 2014 , 2019 ; Qian et al, 2014 ; Qu et al, 2014 ; Raju et al, 2014 ; Sun et al, 2014 , 2015 ; Xiao et al, 2014 ; Jin et al, 2015 ; Nandi et al, 2015 ; Yu et al, 2015 ; Zhang et al, 2015 ; Zhou J. et al, 2015 ; Dai et al, 2016 ; Reja et al, 2016 ; Chen et al, 2017 ; Li et al, 2017 , 2018 , 2019 ; Ma et al, 2017 ; Mahapatra et al, 2017 ; Jung et al, 2019 ; Paul et al, 2019 ; Shi et al, 2019 ; Xing et al, 2019 ; Fang et al, 2020 ; Han et al, 2020 ; Hou et al, 2020 ; Vijay and Velmathi, 2020 ), a few of which were constructed by cleavage of C = C bond (Sun et al, 2014 ; Reja et al, 2016 ; Li et al, 2017 , 2018 , 2019 ; Liu et al, 2019 ; Hou et al, 2020 ). Many examples were developed by the deprotection group from the fluorescent group (Cui et al, 2014 ; Goswami et al, 2014a , 2015 ; Liu et al, 2014 ; Qian et al, 2014 ; Qu et al, 2014 ; Raju et al, 2014 ; Jin et al, 2015 ; Sun et al, 2015 ; Yu et al, 2015 ; Zhang et al, 2015 ; Zhou J. et al, 2015 ; Chen et al, 2017 ; Ma et al, 2017 ; Mahapatra et al, 2017 ; Shi et al, 2019 ; Xing et al, 2019 ; Fang et al, 2020 ; Vijay and Velmathi, …”

Section: Introductionmentioning

confidence: 99%

Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift

Zhang

et al. 2021

Front. Chem.

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Diethyl malonate-based fluorescent probe NE-N2H4 was constructed for monitoring hydrazine (N2H4). The novel probe NE-N2H4 exhibits good properties, such as large Stokes shift (about 125 nm), good selectivity, and low cytotoxicity. This sensing probe NE-N2H4 can be operated to detect hydrazine in living HeLa cells. Especially after soaking in probe solution, the thin-layer chromatography (TLC) plate could detect the vapor of hydrazine. Therefore, the probe NE-N2H4 might be used to monitor hydrazine in biosamples and environmental problem.

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“…However, these conventional methods are not commendably applied in living biosystems due to several common faults, including being time-consuming, meading complicated sample preparation and a sophisticated process. 18,19 In contrast, fluorescence spectroscopy reveals a promising way owing to its ease of operation, being non-invasive, and having highly sensitive and selective properties. [20][21][22][23] To date, many fluorescent sensors for Hg 2+ have been reported.…”

Section: Introductionmentioning

confidence: 99%

Fabrication of Water-soluble Fluorescent Polymeric Micelles for Selective Detection of Hg2+ in Blood Serum

et al. 2017

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In this study, amphiphilic diblock copolymers were designed and synthesized via the incorporation of reversible additionfragmentation chain transfer radical polymerization (RAFT) and a subsequent grafting technique. Subsequently, Hg 2+ -sensitive water-soluble fluorescent polymeric micelles (FNs) were prepared by a reprecipitation strategy. The spectroscopic characteristics demonstrate that the fluorescein isothiocyanate (FITC) was successfully linked into the polymer. Due to the promoted reaction of desulfurization cyclization by Hg 2+ , the fluorescence of fluorescein in FNs was obviously quenched. The as-prepared FNs showed admirable Hg 2+ -sensitivity (detection limit: 54 nM), excellent water-solubility and high selectivity. In addition, FNs were successfully used to determine Hg 2+ in blood serum. We expected that the as-prepared FNs could perform potential applications in imaging, sensing, and bioanalytic chemistry.

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A simple but effective near-infrared ratiometric fluorescent probe for hydrazine and its application in bioimaging

Cited by 62 publications

References 56 publications

Recent progress in the development of fluorescent probes for hydrazine

Recent progress in the development of fluorescent probes for hydrazine

Diethyl Malonate-Based Turn-On Chemical Probe for Detecting Hydrazine and Its Bio-Imaging and Environmental Applications With Large Stokes Shift

Fabrication of Water-soluble Fluorescent Polymeric Micelles for Selective Detection of Hg2+ in Blood Serum

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