A simple AuNPs-based colorimetric aptasensor for chlorpyrifos detection

Liu, Yuan; Li, Taotao; Yang, Gaojian; He, Nongyue; Mou, Xianbo; Deng, Yan

doi:10.1016/j.cclet.2021.11.025

Cited by 64 publications

(20 citation statements)

References 51 publications

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“…The environmental problems of the earth are becoming more and more serious. It is very important to detect the content of environmental pollutants [ 173 , 174 , 175 , 176 , 177 ]. Based on enzymatic reactions, LC molecules can be employed to detect pesticides, as was stated for enzyme detection.…”

Section: Overview Of Lc Droplet-based Biosensors For Poc Diagnosis Of...mentioning

confidence: 99%

Liquid Crystal Droplet-Based Biosensors: Promising for Point-of-Care Testing

Xie

et al. 2022

Biosensors

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The development of biosensing platforms has been impressively accelerated by advancements in liquid crystal (LC) technology. High response rate, easy operation, and good stability of the LC droplet-based biosensors are all benefits of the long-range order of LC molecules. Bioprobes emerged when LC droplets were combined with biotechnology, and these bioprobes are used extensively for disease diagnosis, food safety, and environmental monitoring. The LC droplet biosensors have high sensitivity and excellent selectivity, making them an attractive tool for the label-free, economical, and real-time detection of different targets. Portable devices work well as the accessory kits for LC droplet-based biosensors to make them easier to use by anyone for on-site monitoring of targets. Herein, we offer a review of the latest developments in the design of LC droplet-based biosensors for qualitative target monitoring and quantitative target analysis.

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Section: Overview Of Lc Droplet-based Biosensors For Poc Diagnosis Of...mentioning

confidence: 99%

Liquid Crystal Droplet-Based Biosensors: Promising for Point-of-Care Testing

Xie

et al. 2022

Biosensors

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“…Vision-based biosensors often do not require large instruments and equipment [ 196 , 197 ], and a small microscope [ 198 , 199 ] or a smartphone [ 200 , 201 ] can read out the detection signal through naked-eye observations [ 202 , 203 , 204 ]. Nano- or micromotors are inspired by natural movements, such as those of sperm, bacteria, or molecular motors, and are promising materials in many biomedical applications [ 205 ].…”

Section: Janus Particles For Optical Poctmentioning

confidence: 99%

Application of Janus Particles in Point-of-Care Testing

et al. 2022

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Janus particles (JPs), named after the two-faced Roman god, are asymmetric particles with different chemical properties or polarities. JPs have been widely used in the biomedical field in recent years, including as drug carriers for targeted controlled drug release and as biosensors for biological imaging and biomarker detection, which is crucial in the early detection and treatment of diseases. In this review, we highlight the most recent advancements made with regard to Janus particles in point-of-care testing (POCT). Firstly, we introduce several commonly used methods for preparing Janus particles. Secondly, we present biomarker detection using JPs based on various detection methods to achieve the goal of POCT. Finally, we discuss the challenges and opportunities for developing Janus particles in POCT. This review will facilitate the development of POCT biosensing devices based on the unique properties of Janus particles.

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“…Several biosensors characterized by different transducing mechanisms, for example, electrochemical, optical, or mass-based, have been applied for the detection of CPF during the last decades [ 14 , 17 , 18 ]. Among all, the electrochemical method has recently become an attractive choice because of its quick and highly sensitive response, coupled with the ability to integrate with a wide range of biorecognition elements such as aptamers, enzymes, or antibodies easily [ 19 ].…”

Section: Introductionmentioning

confidence: 99%

“…Similarly, Jiao et al presented a GCE functionalized with chitosan, carbon black, and graphene oxide @Fe 3 O 4 together to produce a complex immobilization matrix for aptamers [ 29 ]. Xu et al [ 30 ] modified the GCE with carboxyl-functionalized single-walled carbon nanotubes (SWCNTs) and electrodeposited cuprous oxide (CuO) nanoflower, obtaining one of the lowest detection limits (0.07 ng/mL) if compared to the other aptasensors [ 4 , 17 , 19 , 31 , 32 ]. Even if the above-cited works showed outstanding performances in terms of sensitivity and LOD, they are made of complex fabrication procedures that involve the use of several materials, reducing the possibility of the scale-up.…”

Section: Introductionmentioning

confidence: 99%

An Aptasensor Based on a Flexible Screen-Printed Silver Electrode for the Rapid Detection of Chlorpyrifos

Inam

Angeli

Douaki

et al. 2022

Sensors

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In this work, we propose a novel disposable flexible and screen-printed electrochemical aptamer-based sensor (aptasensor) for the rapid detection of chlorpyrifos (CPF). To optimize the process, various characterization procedures were employed, including Fourier transform infrared spectroscopy (FT-IR), electrochemical impedance spectroscopy (EIS), and cyclic voltammetry (CV). Initially, the aptasensor was optimized in terms of electrolyte pH, aptamer concentration, and incubation time for chlorpyrifos. Under optimal conditions, the aptasensor showed a wide linear range from 1 to 105 ng/mL with a calculated limit of detection as low as 0.097 ng/mL and sensitivity of 600.9 µA/ng. Additionally, the selectivity of the aptasensor was assessed by identifying any interference from other pesticides, which were found to be negligible (with a maximum standard deviation of 0.31 mA). Further, the stability of the sample was assessed over time, where the reported device showed high stability over a period of two weeks at 4 °C. As the last step, the ability of the aptasensor to detect chlorpyrifos in actual samples was evaluated by testing it on banana and grape extracts. As a result, the device demonstrated sufficient recovery rates, which indicate that it can find application in the food industry.

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A simple AuNPs-based colorimetric aptasensor for chlorpyrifos detection

Cited by 64 publications

References 51 publications

Liquid Crystal Droplet-Based Biosensors: Promising for Point-of-Care Testing

Liquid Crystal Droplet-Based Biosensors: Promising for Point-of-Care Testing

Application of Janus Particles in Point-of-Care Testing

An Aptasensor Based on a Flexible Screen-Printed Silver Electrode for the Rapid Detection of Chlorpyrifos

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