A Simple and Low Cost Micromixer for Laminar Blood Mixing: Design, Optimization, and Analysis

Tran‐Minh, Nhut; Karlsen, Frank; Dong, Tao; Le‐The, Hai

doi:10.1007/978-3-642-54121-6_8

Cited by 12 publications

(6 citation statements)

References 13 publications

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“…The mixing efficiency is the key indicator of micromixer performance, which will directly affect the quality and quantity of various reactions. In order to quantitatively evaluate the degree of mixing in the micromixer, the mixing efficiency was defined as M, and the calculation method is as shown in (5) [19,20]…”

Section: Numerical Simulationmentioning

confidence: 99%

“…The mixing efficiency is the key indicator of micromixer performance, which will directly affect the quality and quantity of various reactions. In order to quantitatively evaluate the degree of mixing in the micromixer, the mixing efficiency was defined as M , and the calculation method is as shown in (5) [19, 20]

M = ()(, 1 - \frac{\int_{0}^{ω} |C - C_{normal∞}| d x}{\int_{0}^{ω} |C_{0} - C_{normal∞}| d x}) \times 100 %

where C is the fluid mass fraction at the outlet, C ∞ is the fluid mass fraction when the mixing is complete (here C ∞ = 0.5 means that the mass fraction of two fluids is the same in each region after the mixing), C 0 is the fluid mass fraction before the start of mixing, and ω is the width of outlet. According to the formula, the mixing efficiency M is in the range of 0–1, and larger the value of M , the higher the mixing efficiency.…”

Section: Numerical Simulationmentioning

confidence: 99%

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Simulation and experimental study of asymmetric split and recombine micromixer with D‐shaped sub‐channels

Xia

Gao

et al. 2019

Micro & Nano Letters

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An effective passive micromixer based on the principles of asymmetric split and recombine has been designed, developed, and investigated to enhance the mixing performance of the micromixer in a microfluidic system. The effects of geometrical parameters and the number of mixing units on mixing performance were studied at different Reynolds (Re) number (ranging from 1 to 80) via CFD software ANSYS CFX. The results revealed that the preferable number of mixing units is 6, and the optimal direction of reducer is opposite to the main channel flow; the D-shaped mixing channel forces the mixed fluid to produce the extended vortex and Dean vortices simultaneously which caused a strong collision at the confluence of fluids, thus leading to the superposition and enhancement of the vortex system; when Re number is 80 and the width ratio of mixing channel W2/W3 = 1, the mixing efficiency of micromixer can exceed 95%.

show abstract

Section: Numerical Simulationmentioning

confidence: 99%

“…The mixing efficiency is the key indicator of micromixer performance, which will directly affect the quality and quantity of various reactions. In order to quantitatively evaluate the degree of mixing in the micromixer, the mixing efficiency was defined as M , and the calculation method is as shown in (5) [19, 20]

M = ()(, 1 - \frac{\int_{0}^{ω} |C - C_{normal∞}| d x}{\int_{0}^{ω} |C_{0} - C_{normal∞}| d x}) \times 100 %

Section: Numerical Simulationmentioning

confidence: 99%

Simulation and experimental study of asymmetric split and recombine micromixer with D‐shaped sub‐channels

Xia

Gao

et al. 2019

Micro & Nano Letters

View full text Add to dashboard Cite

show abstract

“…To investigate quantitatively the mixing performance of the micromixer, the mixing index of the species at a cross section is calculated as follows [ 43 ]:

where M is the mixing index, N is the total number of sampling points, c i and c are normalized concentration and expected concentration, respectively. The mixing index varies from 0 to 1.…”

Section: Model Descriptionsmentioning

confidence: 99%

Mixing Performance of a 3D Micro T-Mixer with Swirl-Inducing Inlets and Rectangular Constriction

Zhang

Luo

2018

Micromachines

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In this paper, three novel 3D micro T-mixers, namely, a micro T-mixer with swirl-inducing inlets (TMSI), a micro T-mixer with a rectangular constriction (TMRC), and a micro T-mixer with swirl-inducing inlets and a rectangular constriction (TMSC), were proposed on the basis of the original 3D micro T-mixer (OTM). The flow and mixing performance of these micromixers was numerically analyzed using COMSOL Multiphysics package at a range of Reynolds numbers from 10 to 70. Results show that the three proposed 3D micro T-mixers have achieved better mixing performance than OTM. Due to the coupling effect of two swirl-inducing inlets and a rectangular constriction, the maximum mixing index and pressure drop appeared in TMSC among the four micromixers especially; the mixing index of TMSC reaches 91.8% at Re = 70, indicating that TMSC can achieve effective mixing in a short channel length, but has a slightly higher pressure drop than TMSI and TMRC.

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“…Passive micromixing generally has microchannels with complex design, special geometry [19], or additional complex obstacles [20] to increase contact with the liquid. Active micromixing mainly relies on the physical field that is exerted outside the microfluidic system.…”

Section: The Microrobot Work As a Mobile Micromixermentioning

confidence: 99%

Magnetic microrobot and its application in a microfluidic system

2014

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This paper researches the design and control method of a microrobot in a microfluidic system by electromagnetic field. The microrobot can move along the microchannel to a required position, and by changing the magnetic torque, the microrobot can also rotate in the microfluidic chip. As an application of the microrobot, it is used as a mobile micromixer to mix two solutions in the microfluidic chip, and the experimental results verify its effectiveness.

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A Simple and Low Cost Micromixer for Laminar Blood Mixing: Design, Optimization, and Analysis

Cited by 12 publications

References 13 publications

Simulation and experimental study of asymmetric split and recombine micromixer with D‐shaped sub‐channels

Simulation and experimental study of asymmetric split and recombine micromixer with D‐shaped sub‐channels

Mixing Performance of a 3D Micro T-Mixer with Swirl-Inducing Inlets and Rectangular Constriction

Magnetic microrobot and its application in a microfluidic system

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