“…With the studies of combination of bioassays, most results appear in Bennett (1962), Armitage (1970), Meisner et al (1986), William (1988), Chen et al (1999), Xiong and Chen (2007), and Chen (2007). Chen et al (1999) proposed a novel empirical Bayesian estimator (EBE) and a shrinkage Bayesian estimator (SBE) for the relative potency from the combination of several multivariate bioassays by incorporating prior information on the model parameters based on Jeffreys' rules.…”