A severe outbreak of orf involving the buccal cavity of goats

Zamri-Saad, M.; Al-Ajeeli, Karim Sadun; Ibrahim, Ab Latif

doi:10.1007/bf02359612

Cited by 8 publications

(9 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The lesions of CPD commonly appears as cauliflower like papillomatous growth or proliferative type (Selbie, 1944;Kummeneje and Krogsrud, 1979;Valder et al, 1979;Tontis et al, 1982;Greig et al, 1984;Zanin et al, 1987;Coates and Hoff, 1990;Zamri-Saad et al, 1992), scabby and granulomatous (Hussain et al, 1992) or dry and crust thick scabs (Verdes et al 1970;Obi and Gibbs, 1978;Noruddin and Barik, 1989;Hawkins et al, 1991) on the mucocutaneous junction and perilabial areas. However, blisters or pearl like lesions, pustule and crusts on the teats and around the mammary gland (Peres, 1932;Slagsvold, 1938;Fontanelli and Caparrini, 1955;Verdes et al, 1970;Larsson and Zahoory, 1983) and papular and pustular lesions around the mouth (Roncero et al, 1989;Housawi et al, 1991;Hussain et al, 1992) and multiple erosive and pustular erruptions in the mouth, cheeks, tongue, lips and part of GIT (Darbyshire, 1961) have also been reported.…”

Section: Advances In Animal and Veterinary Sciencesmentioning

confidence: 99%

“…The incubation period in natural cases of CPD is 2-3 weeks (Coates and Hoff, 1990;Zamri-Saad et al, 1992). Experimentally, the skin lesions in sheep appeared in 4-5 days (Grishaev and Shchepetova, 1970;Willayat and Garg, 1992) and in cats in 8-11 days as a papule followed by degenerative changes leading to pustule formation without undergoing stage of vesiculation (Grishaev and Shchepetova, 1970) and produces erythema multiforme.…”

Section: Advances In Animal and Veterinary Sciencesmentioning

confidence: 99%

“…The clinical signs in captive wild animals were similar to domestic sheep and goats which had poor general body condition and difficulty in feeding (Samuel et.al. 1975) and loss of body weight (Zamri-Saad et al, 1992;Ozturk et al, 2012).…”

Section: Advances In Animal and Veterinary Sciencesmentioning

confidence: 99%

See 2 more Smart Citations

Contagious Pustular Dermatitis (Orf Disease) - Epidemiology, Diagnosis, Control and Public Health Concerns

Kumar¹,

Trivedi²,

Bhatt³

et al. 2015

Adv. Anim. Vet. Sci.

View full text Add to dashboard Cite

| Contagious pustular dermatitis (CPD), also known as Orf or contagious ecthyma is an important viral disease of sheep and goats. It is mainly seen as a benign disease but malignant form has also been reported from few parts of the world. The rates of morbidity and mortality are higher, particularly in lambs and kids experiencing the disease for the first time. The causative agent of disease is Orf virus, type species of the genus Parapoxvirus belonging to family Poxviridae. The virus produces localized persistent proliferative skin lesions and affected hosts are infected repeatedly owing to its host immune evasive strategy. These viruses have been found uniformly labile to chloroform but resistant to ether and also exhibit antigenic variations among them. Clinically, the disease is enzootic and occurs in three forms viz. labial, genital / mammary and generalized forms. The incubation period in natural cases is 2-3 weeks. The disease outbreaks mostly occur between autumn and spring but its severity is more in autumn and winter than spring. The virus grows well in cell cultures of caprine, ovine and bovine origin. Confounding symptoms impose laboratory affirmation by serological assays or molecular techniques. The disease can be diagnosed by electron microscopy, serological tests and PCR/ quantitative real-time PCR. Virus specific antibody response to structural proteins of capripox and orf viruses in western-blot analysis readily differentiates these two infections. The antibody response to the 32 kDa and 26 kDa proteins of capripox viruses provides a firm basis for differentiation. Although, the role of humoral immunity is well established but probably cell mediated immunity plays a major role in recovery from natural infections. A number of inactivated and live or live modified vaccines have been tried with variable success. The duration of immunity after vaccination is controversial; outbreaks have occurred in vaccinated animals. The disease is also of public health significance as it causes infection in human beings. Keywords

show abstract

Section: Advances In Animal and Veterinary Sciencesmentioning

confidence: 99%

Section: Advances In Animal and Veterinary Sciencesmentioning

confidence: 99%

See 1 more Smart Citation

Contagious Pustular Dermatitis (Orf Disease) - Epidemiology, Diagnosis, Control and Public Health Concerns

Kumar¹,

Trivedi²,

Bhatt³

et al. 2015

Adv. Anim. Vet. Sci.

View full text Add to dashboard Cite

show abstract

“…It has been reported that in the case of ecthyma contagiosum disease, typical lesions such as papules, pustules, nodules have been observed following clinical manifestations of weakness, anorexia, hypersalivation, tongue and swelling and redness in the gums [2,11,12] . Typical skin lesions in the clinical examination of the animals used in our study were observed in the group of patient sheep, suggesting similar symptoms in addition to the usual symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…The lesions can usually be cauliflower-like papillomatosis, proliferative, granulomatous, dry crusted, embossed and erosive [5] . The average incubation period in ecthyma contagiosum disease is 2-3 weeks [11,12] . Diagnosis of the disease is easily possible with clinical findings, characteristic skin lesions and histopathological examination findings of these lesions as well as biopsy of the infected skin and visualization of the agent itself in electron microscopy or advanced laboratory techniques like PCR [11] .…”

Section: Introductionmentioning

confidence: 99%

Ecthyma Contagiosa’lı Koyunlarda Paraoksonaz Aktivitesi, Total Sialik Asit ve Oksidatif Stresin Değerlendirilmesi

Deveci¹,

Kükürt²,

Uzlu³

et al. 2017

Kafkas Univ Vet Fak Derg

View full text Add to dashboard Cite

Zoonoses are defined by the world health organization as diseases and infections which are transmitted naturally between vertebrate animals and human. Undestanding the zoonotic risk posed by pox viruses in companion animals is important for both human and animal health. Contagious ecthyma is highly contagious, zoonotic, viral skin disease that affects sheep, goats and some other domesticated and wild animals. In this present study was detected and evaluated levels of plasma paraoxonase activity (PON1), high-density lipoprotein (HDL), total sialic acid (TSA), malondialdehyde (MDA), nitric oxide (NO) and total blood glutathione (GSH) concentrations in healthy sheep and natural infected sheeps with ecthyma. In healthy sheep, laboratory results were determined as PON1 218.54±17.93 U/L, TSA 59.89±5.59 mg/ dL, HDL 48.4±4.88 mg/dL, MDA 8.58±0.80 μmol/L, NO 7.78±1.02 μmol/L and GSH 21.11±3.70 mg/dL. These values were found 174.92±18.68 U/L, 70.1±6.56 mg/dL, 37.9±6.47 mg/dL, 11.26±1.06 µmol/L, 12.44±1.90 µmol/L, 7.79±0.90 mg/dL respectively in sheeps wich are infected by ecthyma. As a result, it was concluded that there is oxidative stress due to imbalance between pro-oxidant and antioxidant molecules in sheep which are infected by ecthyma, and this imbalance is shaped by increasing oxidant levels. Keywords

show abstract

Effect of dexamethasone administration on the pathogenicity and lesion severity in rats experimentally inoculated with Orf virus (Malaysian isolates)

et al. 2018

View full text Add to dashboard Cite

A severe outbreak of orf involving the buccal cavity of goats

Cited by 8 publications

References 4 publications

Contagious Pustular Dermatitis (Orf Disease) - Epidemiology, Diagnosis, Control and Public Health Concerns

Contagious Pustular Dermatitis (Orf Disease) - Epidemiology, Diagnosis, Control and Public Health Concerns

Ecthyma Contagiosa’lı Koyunlarda Paraoksonaz Aktivitesi, Total Sialik Asit ve Oksidatif Stresin Değerlendirilmesi

Effect of dexamethasone administration on the pathogenicity and lesion severity in rats experimentally inoculated with Orf virus (Malaysian isolates)

Contact Info

Product

Resources

About