A Serosurvey of Viral Infections in Lions (Panthera leo), from Queen Elizabeth National Park, Uganda

Driciru, Margaret; Siefert, L.; Prager, Katherine C.; Dubovi, Edward J.; Sande, Robert; Princee, Frank; Friday, Tom; Munson, Linda

doi:10.7589/0090-3558-42.3.667

Cited by 30 publications

(11 citation statements)

References 10 publications

(15 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Carnivore parvoviruses are endemic in most domestic and feral carnivore populations and they infect a variety of host species (see for example [19, 21, 28, 62, 64, 67, 73, 77]). The related group of “FPV-like” viruses, which includes FPV, viruses from raccoons (termed RPV) and arctic foxes (termed blue fox parvovirus (BFPV)), has been widespread for many decades.…”

Section: The Parvoviruses Of Carnivoresmentioning

confidence: 99%

“…The related group of “FPV-like” viruses, which includes FPV, viruses from raccoons (termed RPV) and arctic foxes (termed blue fox parvovirus (BFPV)), has been widespread for many decades. “FPV-like” viruses infect various hosts including domestic and wild cats, lions, tigers, leopards, cougars, lynx, civets, leopard cats, arctic foxes and raccoons [7, 8, 19, 32, 64, 65, 74]. These viruses are all very similar, appear to be transmitted readily among these hosts, and form a monophyletic clade in phylogenetic analyses of the viral sequences [56, 66].…”

Section: The Parvoviruses Of Carnivoresmentioning

confidence: 99%

See 1 more Smart Citation

The emergence of parvoviruses of carnivores

2010

View full text Add to dashboard Cite

The emergence of canine parvovirus (CPV) represents a well-documented example highlighting the emergence of a new virus through cross-species transmission. CPV emerged in the mid-1970s as a new pathogen of dogs and has since become endemic in the global dog population. Despite widespread vaccination, CPV has remained a widespread disease of dogs, and new genetic and antigenic variants have arisen and sometimes reached high frequency in certain geographic regions or throughout the world. Here we review our understanding of this emergence event and contrast it to what is known about the emergence of a disease in mink caused by mink enteritis virus (MEV). In addition, we summarize the evolution of CPV over the past 30 years in the global dog population, and describe the epidemiology of contemporary parvovirus infections of dogs and cats. CPV represents a valuable model for understanding disease emergence through cross-species transmission, while MEV provides an interesting comparison.

show abstract

Section: The Parvoviruses Of Carnivoresmentioning

confidence: 99%

Section: The Parvoviruses Of Carnivoresmentioning

confidence: 99%

The emergence of parvoviruses of carnivores

2010

View full text Add to dashboard Cite

show abstract

“…13 There are also a few studies from Botswana, Uganda and Tanzania, mainly in lions, where the prevalence of FIV was reported to be 71%, while no Ag were detected for FeLV. 14–16 Importantly, no studies have been published regarding the prevalence of FIV or FeLV in Mozambique; although at Eduardo Mondlane University (UEM) Veterinary Faculty Clinic in Maputo, Mozambique, some cats show clinical signs consistent with a clinical diagnosis of infection with one or both viruses.…”

Section: Introductionmentioning

confidence: 99%

Occurrence of feline immunodeficiency virus and feline leukaemia virus in Maputo city and province, Mozambique: a pilot study

Tchamo

Rugeriis

Noormahomed

2019

Journal of Feline Medicine and Surgery Open Reports

View full text Add to dashboard Cite

Objectives Feline immunodeficiency virus (FIV) and feline leukaemia virus (FeLV) are immunosuppressive viruses in cats that increase their susceptibility to zoonotic pathogens. This study aimed to determine the occurrence of one or both viruses, the risk factors associated with infection, and to develop further recommendations. Methods This was a cross-sectional study conducted at the Veterinary Faculty of Eduardo Mondlane University, Mozambique, between March and December 2017, in 145 cats. From each of 145 cats, we took 1.5 ml of blood by jugular puncture for detection of antibodies to FIV and FeLV antigens in whole blood using a commercial test kit, DFV Test FeLV/FIV. Results We found an overall prevalence of 11.0% and 14.5% for FIV antibodies and FeLV antigens, respectively, with four (2.8%) cats coinfected by both pathogens. Male cats were more likely to be infected with FIV (odds ratio [OR] 1.1, 95% confidence interval [CI] 0.3–4.0) compared with female cats. Clinically ill cats were more likely to have a positive result for FeLV antigen infection (OR 18.8, 95% CI 5.2–68.3). Moreover, cats living in suburban areas have a greater chance of a positive result for FeLV infection (OR 3.7, 95% CI 1.4–9.6) compared with cats living in urban areas. Conclusions and relevance FIV and FeLV occur in cats from Maputo and possibly all over the country. Further studies should be conducted in Mozambique and other African countries to define the burden of both pathogens in cats, coinfection with other zoonotic pathogens and the possible role played by the cats on the transmission of zoonotic and opportunistic diseases to humans.

show abstract

“…FeLV infections tend to be rare or absent in many nondomestic felid species [ 9 – 14 ], except for the European wildcat (Felis silvestris silvestris), a species very closely related to the domestic cat, in which FeLV appears to be endemic [ 15 – 17 ]. However, documentation of FeLV is becoming more common in wild felid species less closely related to the genus Felis , which highlights the omnipresent threat that FeLV represents to the conservation of wild felids worldwide.…”

Section: Introductionmentioning

confidence: 99%

Putative progressive and abortive feline leukemia virus infection outcomes in captive jaguarundis (Puma yagouaroundi)

Filoni

Helfer-Hungerbuehler

Catão‐Dias

et al. 2017

Virol J

View full text Add to dashboard Cite

BackgroundFeline leukemia virus (FeLV) is an exogenous gammaretrovirus of domestic cats (Felis catus) and some wild felids. The outcomes of FeLV infection in domestic cats vary according to host susceptibility, virus strain, and infectious challenge dose. Jaguarundis (Puma yagouaroundi) are small wild felids from South and Central America. We previously reported on FeLV infections in jaguarundis. We hypothesized here that the outcomes of FeLV infection in P. yagouaroundi mimic those observed in domestic cats. The aim of this study was to investigate the population of jaguarundis at Fundação Parque Zoológico de São Paulo for natural FeLV infection and resulting outcomes.MethodsWe investigated the jaguarundis using serological and molecular methods and monitored them for FeLV-related diseases for 5 years. We retrieved relevant biological and clinical information for the entire population of 23 jaguarundis held at zoo. Post-mortem findings from necropsies were recorded and histopathological and immunohistopathological analyses were performed. Sequencing and phylogenetic analyses were performed for FeLV-positive samples. For sample prevalence, 95% confidence intervals (CI) were calculated. Fisher’s exact test was used to compare frequencies between infected and uninfected animals. P-values <0.05 were considered significant.ResultsIn total, we detected evidence of FeLV exposure in four out of 23 animals (17%; 95% CI 5–39%). No endogenous FeLV (enFeLV) sequences were detected. An intestinal B-cell lymphoma in one jaguarundi was not associated with FeLV. Two jaguarundis presented FeLV test results consistent with an abortive FeLV infection with seroconversion, and two other jaguarundis had results consistent with a progressive infection and potentially FeLV-associated clinical disorders and post-mortem changes. Phylogenetic analysis of env revealed the presence of FeLV-A, a common origin of the virus in both animals (100% identity) and the closest similarity to FeLV-FAIDS and FeLV-3281 (98.4% identity), originally isolated from cats in the USA.ConclusionsWe found evidence of progressive and abortive FeLV infection outcomes in jaguarundis, and domestic cats were probably the source of infection in these jaguarundis.

show abstract

A Serosurvey of Viral Infections in Lions (Panthera leo), from Queen Elizabeth National Park, Uganda

Cited by 30 publications

References 10 publications

The emergence of parvoviruses of carnivores

The emergence of parvoviruses of carnivores

Occurrence of feline immunodeficiency virus and feline leukaemia virus in Maputo city and province, Mozambique: a pilot study

Putative progressive and abortive feline leukemia virus infection outcomes in captive jaguarundis (Puma yagouaroundi)

Contact Info

Product

Resources

About