A Serological Study of Haemolytic Streptococci

Plummer, Helen

doi:10.1128/jb.30.1.5-20.1935

Cited by 32 publications

(13 citation statements)

References 19 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The distribution of serologic groups of streptococci in human beings seems to be fairly uniform in various parts of the world as far as is shown by the available data from England (Hare, 1935;Hare and Maxted, 1935;Congdon, 1935;Colebrook, Maxted and Johns, 1935), China (Davis and Guzdar, 1936), Japan (Kodama, et al, 1938;Kobayashi, 1939), Australia (Butler, 1938, the Atlantic coast of the United States (Lancefield, 1933;Coffey, 1938;Plummer, 1935;Foote, et al, 1936;Rolfs, Trussell and Plass, 1938), and now the Pacific Coast.…”

Section: Discussionmentioning

confidence: 86%

The Differentiation of Hemolytic Streptococci from Various Sources by the Group Precipitin Reaction and by Biochemical Tests

et al. 1940

View full text Add to dashboard Cite

This study was undertaken, first, to determine the prevalence of the different serologic groups of hemolytic streptococci in specimens collected in this vicinity; and, second, to obtain additional data on the correlation between certain biochemical tests and the group precipitin reaction of Lancefield (1933). A total of 561 cultures was studied of which 188 were isolated from material from human infections, 53 from normal persons, 8 from infected animals, and 312 from raw milk. Several such studies have been made since the Lancefield technic has been available. A similar survey of cultures from human and animal sources was reported by Coffey (1938). Butler (1938), Plummer (1935), Reid and Browne (1939) and Kobayashi (1939) have studied cultures derived chiefly from a variety of human sources. Among others who have classified hemolytic streptococci by the precipitin test are: Hare (1935), Davis and Guzdar (1936), Foote, Welch, West and Borman (1936), and Kodama, Ozaki, Nishiyama and Chiku (1938), who studied cultures from the nose and throat; Hare and Maxted (1935) and Smith and Sherman (1938), who examined human feces; Lancefield and Hare (1935), Rolfs, Trussell and Plass (1938), and Congdon (1935), who collected strains from the vagina and respiratory tract of parturient women; Colebrook, Maxted and Johns (1935), whose cultures were secured from human skin; and Plastridge and Hartsell (1937), Valentine (1938),

show abstract

Section: Discussionmentioning

confidence: 86%

The Differentiation of Hemolytic Streptococci from Various Sources by the Group Precipitin Reaction and by Biochemical Tests

et al. 1940

View full text Add to dashboard Cite

show abstract

“…The production of a orange to brick-red pigment by human GBS strains is a characteristic phenotypic feature reported very early in the literature (Durand & Giraud, 1923;Sherman, 1937;Plummer, 1941). Fallon (1974) proposed the use of pigment detection as a diagnostic tool for GBS identification.…”

Section: Biological Characteristicsmentioning

confidence: 96%

“…A strong link exists between the b-haemolytic phenotype and the production of GBS pigment (Lancefield, 1934;Sherman, 1937;Plummer, 1941). Systematic studies could not identify nonhaemolytic pigmented GBS strains or nonpigmented haemolytic strains (Fallon, 1974;Noble et al, 1983;Tapsall, 1987;Wennestrom et al, 1991).…”

Section: Phenotypic Linkage Of Gbs Haemolysin and Pigment Productionmentioning

confidence: 99%

Group B streptococcal haemolysin and pigment, a tale of twins

Rosa-Fraile¹,

Dramsi²,

Spellerberg³

2014

FEMS Microbiol Rev

View full text Add to dashboard Cite

Group B streptococcus [(GBS or Streptococcus agalactiae)] is a leading cause of neonatal meningitis and septicaemia. Most clinical isolates express simultaneously a β-haemolysin/cytolysin and a red polyenic pigment, two phenotypic traits important for GBS identification in medical microbiology. The genetic determinants encoding the GBS haemolysin and pigment have been elucidated and the molecular structure of the pigment has been determined. The cyl operon involved in haemolysin and pigment production is regulated by the major two-component system CovS/R, which coordinates the expression of multiple virulence factors of GBS. Genetic analyses indicated strongly that the haemolysin activity was due to a cytolytic toxin encoded by cylE. However, the biochemical nature of the GBS haemolysin has remained elusive for almost a century because of its instability during purification procedures. Recently, it has been suggested that the haemolytic and cytolytic activity of GBS is due to the ornithine rhamnopolyenic pigment and not to the CylE protein. Here we review and summarize our current knowledge of the genetics, regulation and biochemistry of these twin GBS phenotypic traits, including their functions as GBS virulence factors.

show abstract

“…All reports concerning hemolysin production by the group D streptococci have dealt with preparations obtained from cells grown in complex media. For example, a serum-beef infusion broth was used by Plummer (18), whereas Irwin and Seeley (17) found that a polynucleotide from yeast autolysate could stimulate the activity of hemolysin when this polynucleotide was used to supplement their neopeptone-beef infusion medium. The studies reported by Brock and his co-workers and Jackson's group have also dealt with hemolysin produced in other complex media: Todd-Hewitt and brain heart infusion (BHI) broths, respectively.…”

mentioning

confidence: 99%

Production of Hemolysin and Bacteriolysin in a Synthetic Medium by Streptococcus faecalis var. zymogenes

Appelbaum

Zimmerman

1974

Infect Immun

View full text Add to dashboard Cite

A synthetic medium has been developed in which Streptococcus faecalis var. zymogenes X-14 elaborates a lysin. The medium consists of 18 amino acids, lactose, six vitamins, adenine, guanine, uracil, and six salts. Glucose, and K,HPO, in excess of 0.5% (wt/vol), were inhibitory to lysin production; increasing concentrations of L-arginine-hydrochloride gave increasing yields of lytic activity. Brock et al. (4), in a survey of the bacteriocins of the enterococci, described a bacteriocin from ' Authorized for publication by The Experiment Station, Pennsylvania State University, as paper no. 4560.

show abstract

A Serological Study of Haemolytic Streptococci

Cited by 32 publications

References 19 publications

The Differentiation of Hemolytic Streptococci from Various Sources by the Group Precipitin Reaction and by Biochemical Tests

The Differentiation of Hemolytic Streptococci from Various Sources by the Group Precipitin Reaction and by Biochemical Tests

Group B streptococcal haemolysin and pigment, a tale of twins

Production of Hemolysin and Bacteriolysin in a Synthetic Medium by Streptococcus faecalis var. zymogenes

Contact Info

Product

Resources

About