A sensitive molecularly imprinted electrochemical aptasensor for highly specific determination of melamine

Yu, Chenhong; Li, Li; Ding, Yaping; Liu, Huajie; Cui, Hanyue; Zhang, Fenfen; Lin, Jiaxin; Duan, Yingchun

doi:10.1016/j.foodchem.2021.130202

Cited by 32 publications

(14 citation statements)

References 39 publications

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“…Although many developed SPEs are commercially available, their real-time application in the milk industry has not become customary as yet. Recently, paper-based devices, pencil graphite electrodes or 3D printed electrochemical sensors have emerged with applications to milk. ,,, Further intriguing developments in the future could be modification of electrochemical sensors by novel molecularly imprinted polymers (MIPs) ,,, and metal organic frameworks (MOFs) , to obtain more selective sensors for milk analysis. MOFs are highly porous and crystalline materials built from the self-assembly of metal ions/clusters and organic ligands through coordination bonding forming 1D, 2D, or 3D structures. − Recent advances in metal oxides (e.g., Fe 2 O 3 , CuO, ZnO, etc.)…”

Section: Recent Advances and Final Remarksmentioning

confidence: 99%

“…84 In another indirect approach, melamine was detected by the DPV method on a preanodized glassy carbon sensor based on melamine competition with uric acid as a recognition element. 11 The combination of molecularly imprinted polymers and melamine aptamer can make a highly sensitive sensor with a low detection limit of 6.7 × 10 −13 M. 172 In a direct detection method of melamine, a dropping mercury electrode was used to detect melamine directly in spiked milk and milk powder samples by differential pulse polarography. 168 No pretreatment methods were applied to these milk samples such as wet digestion or derivatization or preconcentration methods, except for a centrifugation step after spiking the milk samples by melamine solution in acetonitrile.…”

Section: ■ Types Of Sensor Materialsmentioning

confidence: 99%

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Electrochemical Methods for the Analysis of Milk

Motshakeri

Sharma

Phillips

et al. 2022

J. Agric. Food Chem.

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The milk and dairy industries are some of the most profitable sectors in many countries. This business requires close control of product quality and continuous testing to ensure the safety of the consumers. The potential risk of contaminants or degradation products and undesirable chemicals necessitates the use of fast, reliable detection tools to make immediate production decisions. This review covers studies on the application of electrochemical methods to milk (i.e., voltammetric and amperometric) to quantify different analytes, as reported over the last 10 to 15 years. The review covers a wide range of analytes, including allergens, antioxidants, organic compounds, nitrogen-and aldehyde containing compounds, biochemicals, heavy metals, hydrogen peroxide, nitrite, and endocrine disruptors. The review also examines pretreatment procedures applied to milk samples and the use of novel sensor materials. Final perspectives are provided on the future of cost-effective and easy-to-use electrochemical sensors and their advantages over conventional methods.

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Section: Recent Advances and Final Remarksmentioning

confidence: 99%

Section: ■ Types Of Sensor Materialsmentioning

confidence: 99%

Electrochemical Methods for the Analysis of Milk

Motshakeri

Sharma

Phillips

et al. 2022

J. Agric. Food Chem.

View full text Add to dashboard Cite

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“…In the investigation of Sehit [ 55 ], MIP/AuNP sensors had good specificity for glucose in human serum, whereas other sensors without AuNPs could not detect even the highest concentration of the research range. Yu et al [ 56 ] constructed a MIP film on the electrode surface after AuNPs modification, which was generated by electro-polymerization of DA, polythymine aptamers, and melamine (MEL).…”

Section: Applications Of Nanomaterials In Mip Sensorsmentioning

confidence: 99%

Recent Advances of Nanomaterials-Based Molecularly Imprinted Electrochemical Sensors

Dong

Zhang

et al. 2022

Nanomaterials

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Molecularly imprinted polymer (MIP) is illustrated as an analogue of a natural biological antibody-antigen system. MIP is an appropriate substrate for electrochemical sensors owing to its binding sites, which match the functional groups and spatial structure of the target analytes. However, the irregular shapes and slow electron transfer rate of MIP limit the sensitivity and conductivity of electrochemical sensors. Nanomaterials, famous for their prominent electron transfer capacity and specific surface area, are increasingly employed in modifications of MIP sensors. Staying ahead of traditional electrochemical sensors, nanomaterials-based MIP sensors represent excellent sensing and recognition capability. This review intends to illustrate their advances over the past five years. Current limitations and development prospects are also discussed.

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“…However, excessive intake of melamine can cause serious damage to the urinary and reproductive systems, leading to bladder stones, kidney failure, bladder cancer and even death in humans and animals [ 70 ]. Yu et al [ 52 ] developed a sensor based on MIP–aptamer for the highly specific recognition of melamine. AuNPs were synthesized through the simple reduction of sodium citrate.…”

Section: Application Of Mip–aptamer In the Molecular Recognition Of C...mentioning

confidence: 99%

Molecularly Imprinting–Aptamer Techniques and Their Applications in Molecular Recognition

Zhou

Liu

2022

Biosensors

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Molecular imprinting–aptamer techniques exhibit the advantages of molecular imprinting and aptamer technology. Hybrids of molecularly imprinted polymer–aptamer (MIP–aptamer) prepared by this technique have higher stability, binding affinity and superior selectivity than conventional molecularly imprinted polymers or aptamers. In recent years, molecular imprinting–aptamer technologies have attracted considerable interest for the selective recognition of target molecules in complex sample matrices and have been used in molecular recognition such as antibiotics, proteins, viruses and pesticides. This review introduced the development of molecular imprinting–aptamer-combining technologies and summarized the mechanism of MIP–aptamer formation. Meanwhile, we discussed the challenges in preparing MIP–aptamer. Finally, we summarized the application of MIP–aptamer to the molecular recognition in disease diagnosis, environmental analysis, food safety and other fields.

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A sensitive molecularly imprinted electrochemical aptasensor for highly specific determination of melamine

Cited by 32 publications

References 39 publications

Electrochemical Methods for the Analysis of Milk

Electrochemical Methods for the Analysis of Milk

Recent Advances of Nanomaterials-Based Molecularly Imprinted Electrochemical Sensors

Molecularly Imprinting–Aptamer Techniques and Their Applications in Molecular Recognition

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