A Self‐Pumping Dressing with Multiple Liquid Transport Channels for Wound Microclimate Management

Abstract

A microclimate with ventilation and proper wettability near the wound is vital for wound healing. In the case of pressure or absorption of large amounts of wound exudate, maintaining air circulation around the wound is currently a challenge for wound dressings. In this study, a novel self-pumping dressing (FAED) with multiple liquid transport channels is designed by combining a 3D spacer fabric, sodium alginate aerogel, and electrospun membrane. This unique structural design allows FAED to unidirectionally rapidly remove excess biofluid from the wound and transfer it through a special liquid transport channel to a liquid storage layer with a high absorption ratio. Importantly, the air circulation layer of FAED composed of liquid transport channels and spacer yarns provides excellent air permeability in both the horizontal (12.3 L min −1 ) and vertical (272.02 mm s −1 ) directions. Additionally, a lower compression modulus (0.14 MPa) and higher compression strength (0.15 MPa) enable the novel dressing to adapt to body contours and provide good supporting performance, as compared to foam dressings. Combined with its high biocompatibility, this unique dressing has significant potential for wound treatment and intensive care.

ZIF-8/Curcumin-Loaded Electrospun Nanofiber Membrane for Wound Healing

“…Apart from hydrophilicity, air permeability is another key parameter of an exceptional wound dressing. Good air permeability not only promotes gas exchange between the cells and external environment but also keeps the wound moist . According to the literature, the optimal WVTR of a wound dressing is 1920–2400 g/m 2 /day .…”

“…Good air permeability not only promotes gas exchange between the cells and external environment but also keeps the wound moist. 33 According to the literature, the optimal WVTR of a Acid-Responsive Evaluation. The wound environment turns rather acidic during inflammation, which may be exacerbated by chemicals metabolized by bacteria and other microbes.…”

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