A selected ion flow tube study of the reactions of H3O+, NO+ and O2+• with seven isomers of hexanol in support of SIFT-MS

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Section: Resultsmentioning

confidence: 62%

Selected ion flow tube study of the reactions of H₃O⁺ and NO⁺ with a series of primary alcohols in the presence of water vapour in support of selected ion flow tube mass spectrometry

Španěl

Žabka

Zymak

et al. 2017

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“…The kinetics of the O 2 +• /pentane reaction were studied using the Profile 3 SIFT-MS instrument (Instrument Science Ltd, Crewe, UK) in the SIFT mode, as described previously. [51][52][53] O 2 + reagent ions were prepared in a microwave discharge through a mixture of air and water vapour, filtered using an injection mass filter, and injected into the flow tube (5 cm length, 1 cm diameter) into helium carrier gas (1 Torr pressure, 300 K temperature). Known flow rates of the prepared pentane/air mixtures were introduced into the helium carrier gas via a heated calibrated capillary.…”

Section: The Kinetics Of the Reaction Of O 2 +• With Pentane And The mentioning

confidence: 99%

Quantification of pentane in exhaled breath, a potential biomarker of bowel disease, using selected ion flow tube mass spectrometry

Dryahina

Španěl

Pospíšilová

et al. 2013

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“…However, the analysis of mixtures containing regio‐isomeric compounds is indeed a limitation of SIFT‐MS as shown by Smith et al for the analysis of isomers of hexanol. Regio‐isomers may possibly react differently depending on the precursor ion, but this is not the general case …”

Section: Resultsmentioning

confidence: 99%

Direct analysis of aldehydes and carboxylic acids in the gas phase by negative ionization selected ion flow tube mass spectrometry: Quantification and modelling of ion–molecule reactions

Ghislain

Costarramone

Sotiropoulos

et al. 2019

Rationale The concentrations of aldehydes and volatile fatty acids have to be controlled because of their potential harmfulness in indoor air or relationship with the organoleptic properties of agri‐food products. Although several specific analytical methods are currently used, the simultaneous analysis of these compounds in a complex matrix remains a challenge. The combination of positive and negative ionization selected ion flow tube mass spectrometry (SIFT‐MS) allows the accurate, sensitive and high‐frequency analysis of complex gas mixtures of these compounds. Methods The ion–molecule reactions of negative precursor ions (OH−, O•−, O2•−, NO2− and NO3−) with five aldehydes and four carboxylic acids were investigated in order to provide product ions and rate constants for the quantification of these compounds by negative ion SIFT‐MS. The results were compared with those obtained by conventional analysis methods and/or with already implemented SIFT‐MS positive ionization methods. The modelling of hydroxide ion (OH−)/molecule reaction paths by ab‐initio calculation allowed a better understanding of these gas‐phase reactions. Results Deprotonation systematically occurs by reaction between negative ions and aldehydes or acids, leading to the formation of [M − H]− primary ions. Ab‐initio calculations demonstrated the α‐CH deprotonation of aldehydes and the acidic proton abstraction for fatty acids. For aldehydes, the presence of water in the flow tube leads to the formation of hydrated ions, [M − H]−.H2O. With the NO2− precursor ion, a second reaction channel results in ion–molecule association with the formation of M.NO2− ions. Conclusions Except for formaldehyde, all the studied compounds can be quantified by negative ion SIFT‐MS with significant rate constants. In addition to positive ion SIFT‐MS with H3O+, O2+ and NO+ precursor ions, negative ionization with O•−, O2•−, OH−, NO2− and NO3− extends the range of analysis of aldehydes and carboxylic acids in air without a preparation or separation step. This methodology was illustrated by the simultaneous quantification in single‐scan experiments of seven aldehydes and six carboxylic acids released by building materials.