A Scoping Review of the Prevalence of Fascioliasis in Malaysia and Risk Factors for Infection

Abstract

This review aimed to provide a comprehensive overview of ruminant and human fascioliasis in Malaysia and to identify research gaps in knowledge of the prevalence of fascioliasis in Malaysia and risk factors for the disease using available evidence-based data. We conducted a scoping review based on the framework of Arksey and O'Malley. The preferred reporting items for systematic reviews and meta-analyses were used to guide the review process. The citation search was performed between May and September 2018. Using specific keywords, literature published between 1998 to September 2018 was retrieved from electronic databases. Six articles related to fascioliasis in Malaysia were included in the final review from 1,932 screened articles and reports. Five studies focused on ruminants, including cattle, buffaloes, sheep and goats in the states of Terengganu and Perak. The most frequent ruminant fascioliasis outbreaks involved cattle and goats, with a prevalence of 82%-95% and these outbreaks occurred in Terengganu. Only one study examined the risk of fascioliasis in cattle. In the study, the age and sex of the cattle were important risk-related parameters. The search returned only one documented report of a suspected case of human fascioliasis with an atypical clinical presentation. At present, human fascioliasis in Malaysia remains under-reported and its prevalence remains unknown. The data summarised in this review based on existing evidence identifies research gaps on fascioliasis in ruminants and humans.

Chromosomal Aberration of Fasciola Hepatica Acetone Powder: In Vitro Study on Human Lymphocytes

“…These effects may explain in some manner how carcinogenic property of chronic infection with Fascioliasis above liver of their host which may be related to release of toxic parasite substances through various growing phases of it in parasitized location as for liver in case of liver fluke here. In the study of chromatids aberrations which are related to chromosomal aberration also but may be considered as internal genotoxic to chromosomes structure [27,28] . It appear that gap and deletion occurs in the same feature of chromosomal aberration as they are increased in ascending style according to increasing of acetone powder concentration to be 10.1 and 5.4…”

Optimizing methanol synthesis from CO2 using graphene-based heterogeneous photocatalyst under RSM and ANN-driven parametric optimization for achieving better suitability

“…Overtraining must be avoided as it will lead to poor predictive performance and is indicated by increased validation error. 36 The requirement of hidden neurons plays an indispensable role in ANN training. Therefore, the exact number of hidden neurons must be calculated beforehand, as too few or too many hidden neurons will result in poor performance and overtraining.…”

Seasonal Occurrence of Cattle Fascioliasis in Kelantan, Malaysia

“…Globally, the production losses due to fascioliasis in livestock were estimated to be over USD 3 billion annually [ 7 ]. In Malaysia, an alarming occurrence of cattle and other ruminant fascioliasis has been reported in several states in the peninsular Malaysia as well as in Sabah [ 8 , 9 ].…”