A scheme for assessing the performance characteristics of small field-of-view gamma cameras

Bhatia, B.S.; Bugby, Sarah L.; Lees, J.E.; Perkins, Alan C.

doi:10.1016/j.ejmp.2014.08.004

Cited by 24 publications

(17 citation statements)

References 23 publications

(25 reference statements)

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“…The NEMA protocols provide a standard platform for comparing various gamma cameras regarding their performance parameters [36]. Table 2 compares the main features of our gamma camera with other small gamma cameras reported in the literature or used as commercial systems.…”

Section: Discussionmentioning

confidence: 99%

Design and development of a dedicated portable gamma camera system for intra-operative imaging

et al. 2016

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Section: Discussionmentioning

confidence: 99%

Design and development of a dedicated portable gamma camera system for intra-operative imaging

et al. 2016

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“…These values were collected and used to produce a histogram for differential uniformities. The mean and dispersion of this distribution were used as a measure of DU (Bhatia et al 2015).…”

Section: Intrinsic Performances Of the Cameramentioning

confidence: 99%

A mobile high-resolution gamma camera for therapeutic dose control during radionuclide therapy

et al. 2022

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Objective. Molecular radiotherapy is the most used treatment modality against malign and benign diseases of thyroid. In that context, the large heterogeneity of therapeutic doses in patients and the range of effects observed show that individualized dosimetry is essential for optimizing treatments according to the targeted clinical outcome. Approach. We developed a high-resolution mobile gamma camera specifically designed to improve the quantitative assessment of the distribution and biokinetics of 131I at patients’s bedside after treatment of thyroid diseases. The first prototype has a field of view of 5×5 cm2 and consists of a high-energy parallel-hole collimator made of 3D-printed tungsten, coupled to a 6 mm thick CeBr3 scintillator readout by an array of silicon photomultiplier detectors. The intrinsic and overall imaging performance of the camera was evaluated with 133Ba and 131I sources. In order to test its quantification capability in realistic clinical conditions, two different 3D-printed thyroid phantoms homogeneously filled with 131I were used. Both single view and conjugate view approaches have been applied, with and without scatter correction technique. Main Results. The camera exhibits high imaging performance with an overall energy resolution of 7.68±0.01%, a submillimetric intrinsic spatial resolution of 0.74±0.28 mm and a very low spatial distortion 0.15±0.10 mm. The complete calibration of the camera shows an overall spatial resolution of 3.14±0.03 mm at a distance of 5 cm and a corresponding sensitivity of 1.23±0.01 cps/MBq, that decreases with distance and slightly changes with source size, due to the influence of scattering. Activity recovery factors better than 97% were found with the thyroid phantoms. Significance. These preliminary results are very encouraging for the use of our camera as a tool for accurate quantification of absorbed doses and currently motivates the development of a fully operational clinical camera with a 10×10 cm2 field of view and improved imaging capabilities.

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“…For the performance evaluation of the system, the sensitivity, the light output, the spatial resolution and the energy resolution values were investigated. The experimental procedures to measure these parameters were based on previously published literature of small field of view gamma cameras with pixelated detectors [28][29][30][31][32][33].…”

Section: Performance Measurementsmentioning

confidence: 99%

Monte Carlo Optical Simulations of a Small FoV Gamma Camera. Effect of Scintillator Thicknesses and Septa Materials

et al. 2019

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Optical Monte Carlo simulations have been extensively used for the accurate modeling of light transport in scintillators for the improvement of detector designs. In the present work, a GATE Monte Carlo toolkit was used to study the effect of scintillator thicknesses and septa materials in the performance parameters evaluation of a commercially available small animal gamma-optical camera, named “γ-eye”. Firstly, the simulated γ-eye system was validated against experimental data. Then, part of the validated camera was modeled defining all of the optical properties by means of the UNIFIED model of GATE. Different CsI:Na scintillator crystals with varying thicknesses (from 4 mm up to 6 mm) and different reflector (septa) materials were simulated and compared in terms of sensitivity, light output and spatial resolution. Results have demonstrated the reliability of the model and indicate that the thicker crystal array presents higher sensitivity values, but degraded spatial resolution properties. Moreover, the use of black tape around crystals leads to an improvement in spatial resolution values compared to a standard white reflector material.

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A scheme for assessing the performance characteristics of small field-of-view gamma cameras

Cited by 24 publications

References 23 publications

Design and development of a dedicated portable gamma camera system for intra-operative imaging

Design and development of a dedicated portable gamma camera system for intra-operative imaging

A mobile high-resolution gamma camera for therapeutic dose control during radionuclide therapy

Monte Carlo Optical Simulations of a Small FoV Gamma Camera. Effect of Scintillator Thicknesses and Septa Materials

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