A scanning electron microscopic study of small pathological lesions of human colonic cancer

Abstract

Abstract. Sixty-five small colonic lesions, less than 20 mm in diameter, were studied by scanning electron microscopy (SEM). They appeared protruded or depressed colonoscopically and were excised from 35 patients by strip biopsy. As a result, crypt orifices on the mucosal surfaces of the depressed lesions were less than 10 am in diameter. In the depressed lesions and in the carcinoma, mucosal epithelial cells and goblet cells were displaced, and partial mucosal destruction existed in the carcinoma.