A sandwich-type electrochemical immunosensor for detecting CEA based on CeO2-MoS2 absorbed Pb2+

Li, Wenjun; Qiao, Xiuwen; Ma, Chaoyun; Song, Yiju

doi:10.1016/j.ab.2019.113566

Cited by 29 publications

(16 citation statements)

References 28 publications

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“…The authors emphasized that the sensor could be used for the POCT of CEA from human serum. Aside from MNP-carbon material-based composites, metal oxide NPs, core shell MNPs, quantum dot NPs, graphene, MOF, etc., have extensively been studied as the electrode probes for fabricating both labeled or label-free sandwich immunosensing arrays for the ultrasensitive detection of CEA for early-stage cancer diagnoses [196,202,209,[211][212][213][214][215][216].…”

Section: Mnps In Cancer Biomarker Detectionmentioning

confidence: 99%

Metal Nanoparticles for Electrochemical Sensing: Progress and Challenges in the Clinical Transition of Point-of-Care Testing

et al. 2020

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With the rise in public health awareness, research on point-of-care testing (POCT) has significantly advanced. Electrochemical biosensors (ECBs) are one of the most promising candidates for the future of POCT due to their quick and accurate response, ease of operation, and cost effectiveness. This review focuses on the use of metal nanoparticles (MNPs) for fabricating ECBs that has a potential to be used for POCT. The field has expanded remarkably from its initial enzymatic and immunosensor-based setups. This review provides a concise categorization of the ECBs to allow for a better understanding of the development process. The influence of structural aspects of MNPs in biocompatibility and effective sensor design has been explored. The advances in MNP-based ECBs for the detection of some of the most prominent cancer biomarkers (carcinoembryonic antigen (CEA), cancer antigen 125 (CA125), Herceptin-2 (HER2), etc.) and small biomolecules (glucose, dopamine, hydrogen peroxide, etc.) have been discussed in detail. Additionally, the novel coronavirus (2019-nCoV) ECBs have been briefly discussed. Beyond that, the limitations and challenges that ECBs face in clinical applications are examined and possible pathways for overcoming these limitations are discussed.

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Section: Mnps In Cancer Biomarker Detectionmentioning

confidence: 99%

Metal Nanoparticles for Electrochemical Sensing: Progress and Challenges in the Clinical Transition of Point-of-Care Testing

et al. 2020

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“…Square wave voltammetry measurements employing the Pb 2+ electrical signal demonstrated a limit of detection, e.g., 0.3 pg mL À1 of CEA. 133 A sandwich type photoelectrochemical (PEC) immunosensor was developed for the detection of brain natriuretic peptide (BNP). The photoactive CeO 2 -CdS platform employs SiO 2 /PDA-Ag nanocomposites for signal amplication.…”

Section: Electrochemical Biosensorsmentioning

confidence: 99%

Synthesis and characterization of nanoceria for electrochemical sensing applications

et al. 2021

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“…The binding molecule needs to be modified, few choices of binding molecules [28,29] noble metal nanoparticles -mediated simple, facile, stable, wide variety of binding molecules, properties enhanced complicated preparation process [30][31][32][33][34][35][36]…”

Section: Chemical Interaction Stablementioning

confidence: 99%

Molybdenum Disulfide-Based Nanoprobes: Preparation and Sensing Application

et al. 2022

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The use of nanoprobes in sensors is a popular way to amplify their analytical performance. Coupled with two-dimensional nanomaterials, nanoprobes have been widely used to construct fluorescence, electrochemical, electrochemiluminescence (ECL), colorimetric, surface enhanced Raman scattering (SERS) and surface plasmon resonance (SPR) sensors for target molecules’ detection due to their extraordinary signal amplification effect. The MoS2 nanosheet is an emerging layered nanomaterial with excellent chemical and physical properties, which has been considered as an ideal supporting substrate to design nanoprobes for the construction of sensors. Herein, the development and application of molybdenum disulfide (MoS2)-based nanoprobes is reviewed. First, the preparation principle of MoS2-based nanoprobes was introduced. Second, the sensing application of MoS2-based nanoprobes was summarized. Finally, the prospect and challenge of MoS2-based nanoprobes in future were discussed.

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A sandwich-type electrochemical immunosensor for detecting CEA based on CeO2-MoS2 absorbed Pb2+

Cited by 29 publications

References 28 publications

Metal Nanoparticles for Electrochemical Sensing: Progress and Challenges in the Clinical Transition of Point-of-Care Testing

Metal Nanoparticles for Electrochemical Sensing: Progress and Challenges in the Clinical Transition of Point-of-Care Testing

Synthesis and characterization of nanoceria for electrochemical sensing applications

Molybdenum Disulfide-Based Nanoprobes: Preparation and Sensing Application

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