A Role for Opioids in Chronic Pain Management

McCarberg, Bill; Hahn, Kathryn L.; Twillman, Robert K.; Hodgkiss-Harlow, Chelsea J.

doi:10.1001/archinternmed.2012.882

Cited by 3 publications

(2 citation statements)

References 5 publications

(2 reference statements)

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“…Some patients, especially those with mental health disorders or substance abuse disorders, exploit physician's sensitivity towards pain and increasingly demand opioids for pain relief. Pain experts have encouraged CP treatment with opioids because: of the established efficacy in controlling acute pain, surgical pain and cancer pain, clinical trials report opioids decrease pain in CNCP [29,30] and drug abuse and addiction is reported to be rare in CP [18,31]. Accordingly, opioids have been prescribed liberally with the expectations that pain will decrease and activity, mood, function and quality of life (QoL) will improve in patients with CP.…”

mentioning

confidence: 99%

Chronic pain treatment with opioid analgesics: benefits versus harms of long-term therapy

Sehgal¹,

Colson²,

Smith³

2013

Expert Review of Neurotherapeutics

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Chronic non-cancer pain (CNCP) is a disabling chronic condition with a high prevalence rate around the world. Opioids are routinely prescribed for treatment of chronic pain (CP). In the past two decades there has been a massive increase in the number of opioid prescriptions, prescribed daily opioid doses and overall opioid availability. Many more patients with CNCP receive high doses of long-acting opioids on a long-term basis. Yet CP and related disability rates remain high, and majority of the patients with CNCP are dissatisfied with their treatments. Intersecting with the upward trajectory in opioid use are the increasing trends in opioid related adverse effects, especially prescription drug abuse, addiction and overdose deaths. This complex situation raises questions on the relevance of opioid therapy in the treatment of CNCP. This article reviews current evidence on opioid effectiveness, the benefits and harms of long-term therapy in CNCP.

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confidence: 99%

Chronic pain treatment with opioid analgesics: benefits versus harms of long-term therapy

Sehgal¹,

Colson²,

Smith³

2013

Expert Review of Neurotherapeutics

View full text Add to dashboard Cite

show abstract

“…Unfortunately, because of the pitfalls listed above, physicians all too frequently decline to provide needed care to alleviate this subjective though potentially profoundly destructive modality and in so doing 'do harm' [42]. The problem is compounded by the fact that treatment options are limited and many of the options at the physician's disposal for treating pain are recognized for their alternate and therapeutically undesirable features that are frequently misused and thus detrimental to the users or are used for illicit, non-therapeutic reasons that have untoward negative effects on society [43][44][45][46][47][48].…”

Section: Basic Assumptionsmentioning

confidence: 99%