A review on updates in management and Treatment of Psoriasis

Alhammad, Ibtihal M.; Aseri, Amal M.; Alqahtani, Sultan A. M.; Alshaebi, Malak F.; Alqahtani, Shahad A.; Alzahrani, Rawan A.; Alhaji, Ahmed A.; Alamoudi, Mohammed K.; Bafarat, Ammar Y.; Jad, Ammar Y.; Nuqali, Alaa E.

doi:10.51847/g6snno5aba

Cited by 11 publications

(9 citation statements)

References 28 publications

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“…As well the finding was supported by Zhang (34) Concerning psoriasis sites, the results of the present study illustrated that the most common psoriasis sites reported in both groups were knee and elbow followed by the hair scalp. These findings were in accordance with Alhammad et al (26) who stated that the most common sites were on the extensor surfaces of the limbs.…”

Section: Continuing Talking About Risk Factorssupporting

confidence: 92%

“…These findings were in agreement with a recent study conducted at Banha city by Mohamed et al (33) about "Knowledge and Self-Care Practices among Psoriatic Patients in Benha City" and showed that the chief complaints of the studied patients were scaling of the skin, itching, erythema, and fatigue. In the same line with the above-mentioned findings Alhammad et al (26) confirmed that classical clinical manifestations are sharply demarcated raised lesions covered in silvery scales. As well the finding was supported by Zhang (34) Concerning psoriasis sites, the results of the present study illustrated that the most common psoriasis sites reported in both groups were knee and elbow followed by the hair scalp.…”

Section: Continuing Talking About Risk Factorssupporting

confidence: 75%

“…However, this result was inconsistent with Najafi Ghezeljeh et al (6) who mentioned that the mean (SD) duration of the disease in the intervention and control groups were Alhammad et al (26) in a study on "A review on Updates in Management and Treatment of Psoriasis" who clarified that psoriasis Vulgaris (plaque) is the most prevalent type in around 90% of cases.…”

Section: Regarding the Source Of Informationmentioning

confidence: 89%

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Effect of Individualized Guidance on Knowledge and Self-Care Practices of Psoriasis Patients

Elzehiri

Srour

Salime

2022

Tanta Scientific Nursing Journal

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Background: Psoriasis is a chronic, immune-multisystem, inflammatory disease that affects the skin and joints and there is a necessity for monitoring and educating patients about benefits as well as risks that may be correlated. Aim: Evaluate the effect of individualized guidance on knowledge and self-care practices of psoriasis patients. Subjects and methods:Design: A quasiexperimental design was utilized. Setting: The study was conducted at the Dermatology outpatient clinic at El-Mansoura University Hospitals. Sample: Purposive sample of 100 adult patients diagnosed with psoriasis from both sexes and they equally divided into study & control groups, (50) patients for each one. Tools: Two tools were used for data collection; the first tool was a structured interviewing questionnaire, and the second tool was the psoriasis disability index. Results: Mean age of the studied psoriasis patients in the study and control group were 44±8.6 and 42± 7.9 respectively. There was a highly statistically significant difference between the study and the control group in all items of psoriasis knowledge (p-value > 0.001). As well there were highly statistically significant differences between both groups post individualized guidance implementation regarding reported skincare and psoriasis affected areas in all items with (p-value > 0.001). There was a significant difference between the study and control group in the total level of disability post individualized guidance (P > 0.001). Conclusion: Implementation of individualized guidance had a positive effect on patients' knowledge and overall reported self-care practices including skincare and self-esteem with a decrease of the level of psoriasis disability, additionally a positive correlation between total scores of knowledge and total scores of reported practices were found. Recommendations: Individualized guidance should be recommended as a nursing intervention protocol during the care of every patient with psoriasis.

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Section: Continuing Talking About Risk Factorssupporting

confidence: 92%

Section: Continuing Talking About Risk Factorssupporting

confidence: 75%

Section: Regarding the Source Of Informationmentioning

confidence: 89%

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Effect of Individualized Guidance on Knowledge and Self-Care Practices of Psoriasis Patients

Elzehiri

Srour

Salime

2022

Tanta Scientific Nursing Journal

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“…Almost 80% of the affected patients present with mild to moderate psoriasis [ 4 , 9 ]. Depending on disease severity, topical treatment, phototherapy, photochemotherapy, and systemic treatment may be used [ 8 , 9 , 10 ]. Apart from topical and systemic pharmacotherapy, adequate skincare is necessary to maintain remission of the skin lesions [ 11 ].…”

Section: Introductionmentioning

confidence: 99%

Phytoecdysteroids from Serratula coronata L. for Psoriatic Skincare

et al. 2022

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Phytoecdysones from Serratula coronata seem to be promising agents for skincare in patients with psoriasis. The aim of the study was to determine the effects of creams containing the extract of S. coronata on psoriatic lesions. Creams with different formulas were prepared: 0-Lekobaza®, 1-Lekobaza®, S. coronata, 2-Lekobaza®, Salicylic acid, 3-Lekobaza®, S. coronata, Salicylic acid. After examination of skin penetration and biosafety, the designated cream was applied twice daily for 6 weeks on 72 psoriatic plaques located on elbows or knees. The lesions were assessed at baseline and follow-up of 6 weeks. The lesions area was measured, and severity of scaling, erythema, and infiltration was assessed using a 5-point scale (from 0—none to 4—very severe). Skin hydration and structure, pH, transepidermal water loss, erythema, and melanin index were analyzed instrumentally. Creams 1, 2, and 3 significantly reduced the area of psoriatic plaques. Improvement in erythema and infiltration was observed for creams 1 and 3. Creams 1–3 reduced scaling. Our study confirmed a beneficial effect of creams containing S. coronata extract on psoriatic lesions.

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“…Even with localized lesions on the face or extremities, psoriasis had long been called "'the badge of shame". 1,2 Though many treatment options are available for localized psoriasis, each has its limitations and side effects. Therefore, the need for an effective topical agent that delivers the drug efficiently into the target site with minimal systemic side effects remains an aim in itself.…”

Section: Introductionmentioning

confidence: 99%

Clinical, dermoscopic, and histopathologic evaluation of topical methotrexate 1% hydrogel versus topical Calcipotriol 0.005% cream in the treatment of plaque psoriasis

Gayar

Atwa

Girgis

et al. 2022

J of Cosmetic Dermatology

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Background: Psoriasis Vulgaris is a common immune-mediated skin disease. Its high prevalence, disability, chronicity, disfiguration, and associated comorbidities make it a challenge for physicians. Topical agents remain the mainstay of treatment for patients with mild to moderate psoriasis. Aim:To evaluate the efficacy and tolerability of topical methotrexate 1% gel (MTX) versus topical calcipotriol 0.005% cream (CPL) in the treatment of localized plaque psoriasis.Methods: This prospective comparative study included 40 patients with localized plaque psoriasis instructed to apply MTX to one side (group A) and CPL to the other side lesions (group B) twice daily for 12 weeks. Clinical and dermoscopic evaluations before, weekly during and after 3 months of treatment were done. The immunohistopathological assessment was done for skin biopsies from 10 patients in each group before and after treatment.Results: At the end of 12 weeks, there was marked-complete improvement in 97.5% of group A lesions treated with MTX 1% gel compared with 37.5% of group B lesions treated with calcipotriol 0.005% cream (p < 0.001). There was a very high statistically significant improvement in erythema that was cleared totally in 67.5% vs 22.5%, scaling in 75% vs 17.5%, and infiltration in 72.5% vs 27.5% in group A vs B, respectively (p < 0.001). These results were confirmed by dermoscopic and immunohistopathological findings. Conclusion:Methotrexate 1% gel is a marvelous promising well-tolerated effective topical agent that can be used safely in the treatment of localized plaque psoriasis.

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A review on updates in management and Treatment of Psoriasis

Cited by 11 publications

References 28 publications

Effect of Individualized Guidance on Knowledge and Self-Care Practices of Psoriasis Patients

Effect of Individualized Guidance on Knowledge and Self-Care Practices of Psoriasis Patients

Phytoecdysteroids from Serratula coronata L. for Psoriatic Skincare

Clinical, dermoscopic, and histopathologic evaluation of topical methotrexate 1% hydrogel versus topical Calcipotriol 0.005% cream in the treatment of plaque psoriasis

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