A review on traditional uses, phytochemistry and pharmacology of Eclipta prostrata (L.) L.

Li, Feng; Zhai, Yuanyuan; Xu, Jia; Yao, Weifeng; Cao, Yudan; Cheng, Fang; Bao, Beihua; Zhang, Li

doi:10.1016/j.jep.2019.112109

Cited by 67 publications

(57 citation statements)

References 74 publications

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“…Until now, approximately 80% of the world's population still use traditional herbal medicines [2]. In fact, herbal medicines can serve as complementary or alternative therapies for different types of diseases because of their low cost, availability, and generally fewer side effects [3]. Several FDA-approved drugs including artemisinin (from Artemisia annua), quinine (from Cinchona officinalis), vinblastine, vincristine, vinorelbine (from Vinca rosea), and etoposide (from Mayapple) primarily originate from traditional herbal medicines [4].…”

Section: Introductionmentioning

confidence: 99%

Ethnobotany of the medicinal plants used by the ethnic communities of Kerman province, Southeast Iran

Hosseini

Bibak

Ghara

et al. 2021

J Ethnobiology Ethnomedicine

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Background Traditional medicine is a major component in the primary healthcare system in the southeast of Iran, which has a rich floral diversity. However, there is no comprehensive report on the use of medicinal herbs in this specific region. This traditional usage of medicinal plants by local communities could serve as a source for pharmacological and phytochemical studies. The main objective of this study was to identify ethnopharmacological knowledge on medicinal plant species and their local healing applications by the folk communities of Kerman province in the southeast of Iran. Methods In this cross-sectional study, data were collected from 217 herbal healers using semi-structured questionnaires, open interviews, and field surveys. Factors including use reports (UR) for each species, frequency of citation (FC), and informant consensus factor (ICF) were used to analyze the data. Plant species were identified by botanists through standard taxonomic methods. Results A total of 402 medicinal plants were used in healing practices by the local communities of Kerman province. These species belong to 273 genera of 73 families, among which 367 species are dicotyledons, 27 are monocotyledons, 7 species are cryptogam, and one species is gymnosperm. An important implication from the current study is the identification of the traditional medicinal use of 292 plant species in this region for the first time. Asteraceae, Apiaceae, Lamiaceae, and Fabaceae were the dominant medicinally utilized plant families, respectively. Leaf, flower, fruit, and seed were the most common plant parts used. Generally, crude drugs were used in the form of decoction, followed by poultice and infusion forms. Moreover, oral route is considered as the most common administration route followed by topical route. Endocrine (diabetes), dermatological, gastrointestinal, and respiratory problems were ranked as the most frequent ailment categories for which medicinal plants in this region were applied, respectively. Our findings suggested dominant use of Asteraceae and Apiaceae plants for the treatment of gastrointestinal disorders, Lamiaceae plants for respiratory and gastrointestinal ailments, and Apocynaceae plants for dermatological problems. Conclusion Our findings suggested that Asteraceae and Apiaceae plants were used for the treatment of gastrointestinal disorders, Lamiaceae plants for respiratory and gastrointestinal ailments, and Apocynaceae and Euphorbiaceae plants for dermatological problems. Among the medicinal plants with high UR and new ethnobotanical uses, Rhazya stricta was used for wound healing, Calotropis procera, Clematis ispahanica and Euphorbia spp. for eczema, Cionura erecta for the treatment of cough, Launaea acanthodes for the treatment of gastrointestinal parasites, Berberis integrrima as an antidiabetic medicinal herb, Dracocephalum polychaetum and Rydingia persica for various types of chronic diseases, Citrus limon and Citrus aurantium for the treatment of ocular diseases and making the traditional kohl, Calendula officinalis for the treatment of pterygium and Prosopis farcta for preventing nasal bleeding. The identified medicinal plants can be further evaluated for their pharmacological activity and underlying mechanisms of action.

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Section: Introductionmentioning

confidence: 99%

Ethnobotany of the medicinal plants used by the ethnic communities of Kerman province, Southeast Iran

Hosseini

Bibak

Ghara

et al. 2021

J Ethnobiology Ethnomedicine

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“…It has been used for nourishing yin and kidney in the clinic. Many indications have shown that it has potential therapeutic effects on NS 10,11 . Recently, accumulating studies have shown that Eclipta prostrata L. has a variety of pharmacological activities such as lowering blood lipid, 12 antioxidant, 13–15 anti‐inflammatory, 16,17 and immunomodulation 18 .…”

Section: Introductionmentioning

confidence: 99%

The combination of HPLC and biological analysis to determine the quality markers and its structural composition of Eclipta prostrata L.

Wang¹,

Huang²,

Li³

et al. 2020

Phytochemical Analysis

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Introduction: The diversity and complexity of components are important reasons for the unstable efficacy and safety of Chinese materia medica (CMM) in quality control. The good and stable quality control may be related to the quality markers with structural composition of multi-components. Objective: In the present study, we take Eclipta prostrata L. as a representative example. The 11 samples were collected from the different areas in China, and the discrepancy in bioactivity and chemical composition of these samples were compared. DOX (doxorubicin hydrochloride)-induced ICR mice were established for in vivo nephrotic syndrome experiments. The biochemical indicators including 24-h urine protein, triglyceride (TG), etc. were measured and the pathological change of kidney tissue was observed. MPC-5 cells damage model was induced to compare the difference of these samples in bio-activity. High-performance liquid chromatography (HPLC) method for 11 EEP (extract of Eclipta prostrata L.) samples were performed to analyse the content of the quality markers. Results: In vivo experiments, EEP could mitigate the content or activity of urine protein, TG, etc. compared with the positive group (TG content was 2.53 ± 0.39 mmol/L, urinary protein quantification on 35th day was 16.79 ± 2.32 mg). In vitro experiments, CCE (coumestans component of Ecliptae) and EEP had equivalent effects on biochemical indicators such as cell viability, etc. According to the HPLC analysis, the content of wedelolactone was 45.88% and demethylwedelolactone was 23.74% in CCE. Conclusion: The CCE with a ratio of 2:1 can be considered as a quality marker of Eclipta prostrata L.. This research may provide a perspective for quality control of CMM.

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“…The plant is covered with flowers throughout the year. The fruiting period of E. alba is from September to October [53][54][55].…”

Section: Botanical Description Of E Alba (Bhringraj)mentioning

confidence: 99%

Eclipta Alba (Bhringraj): A Promising Hepatoprotective and Hair Growth Stimulating Herb.

Kumari¹,

Kaurav²,

Chaudhary³

2021

Asian J Pharm Clin Res

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Plants are the primary source of food, shelter, and various remedial approaches. They are being in use for treating various kinds of human ailments across the world since the ancient times. One of such important plants is Eclipta alba hassk (Asteraceae) which is commonly known as Bhringraj and false daisy. This plant is known for its extra-ordinary therapeutic properties. It is one of most widely used plant in traditional systems of medicines such as Ayurvedic, Unani, Sidha, homeopathy, Chinese, and folk. Each part of this medicinal plant contains many important phytochemical constituents such as coumestans, triterpenes, flavonoids, steroids, polypeptides, and saponins. It is majorly used for enhancing the growth, strength, and blackening of hair. It is used as the main ingredient in many hair oils. It significantly treats problems related to hair such as hair fall, dandruff, premature greying, and baldness. E. alba exhibits many other important biological properties such as anticancer, anti-bacterial, anti-viral, anti-stress, and immunomodulatory. Thus, this medicinal plant is playing a vital role in the medical field and cosmetic industry. The present review is a summary of phytomedicinal importance of E. alba in Ayurveda as well as folk medicine system.

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A review on traditional uses, phytochemistry and pharmacology of Eclipta prostrata (L.) L.

Cited by 67 publications

References 74 publications

Ethnobotany of the medicinal plants used by the ethnic communities of Kerman province, Southeast Iran

Ethnobotany of the medicinal plants used by the ethnic communities of Kerman province, Southeast Iran

The combination of HPLC and biological analysis to determine the quality markers and its structural composition of Eclipta prostrata L.

Eclipta Alba (Bhringraj): A Promising Hepatoprotective and Hair Growth Stimulating Herb.

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