A review on thermal analyses of cyclodextrins and cyclodextrin complexes

Hădărugă, Nicoleta G.; Bandur, Geza; Dávid, I.; Hădărugă, Daniel I.

doi:10.1007/s10311-018-0806-8

Cited by 100 publications

(50 citation statements)

References 100 publications

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“…The pristine HP-β-CyD nanofibers are in the amorphous state and have shown a broad peak in the range of 30-140 °C due to water loss. 67 The DSC thermogram of hydrocortisone/HP-β-CyD (1/1) nanofibers shows an endothermic peak at 209 °C having a peak area of ∼13.5 J g −1 due to the melting of hydrocortisone crystals. The physical mixture of hydrocortisone/HP-β-CyD (1/1) has also shown a melting peak at 210 °C with a peak area of 18.5 J g −1 .…”

Section: Structural Characterizationmentioning

confidence: 98%

Hydrocortisone/cyclodextrin complex electrospun nanofibers for a fast-dissolving oral drug delivery system

Çelebioğlu

Uyar

2020

RSC Med. Chem.

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Section: Structural Characterizationmentioning

confidence: 98%

Hydrocortisone/cyclodextrin complex electrospun nanofibers for a fast-dissolving oral drug delivery system

Çelebioğlu

Uyar

2020

RSC Med. Chem.

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“…They are derived from starch and they are composed of several D-glucose units. The arrangement of the monomers can be simulated with a truncated cone, where the secondary and primary hydroxyl groups are projected on the wide and narrow rim, respectively, forming a hydrophilic exterior, while CH 2 groups and glucosidic oxygen atoms consist the hydrophobic interior cavity of the cone [ 17 , 18 ].…”

Section: Introductionmentioning

confidence: 99%

Nanosystems for the Encapsulation of Natural Products: The Case of Chitosan Biopolymer as a Matrix

et al. 2020

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Chitosan is a cationic natural polysaccharide, which has emerged as an increasingly interesting biomaterialover the past few years. It constitutes a novel perspective in drug delivery systems and nanocarriers’ formulations due to its beneficial properties, including biocompatibility, biodegradability and low toxicity. The potentiality of chemical or enzymatic modifications of the biopolymer, as well as its complementary use with other polymers, further attract the scientific community, offering improved and combined properties in the final materials. As a result, chitosan has been extensively used as a matrix for the encapsulation of several valuable compounds. In this review article, the advantageous character of chitosan as a matrix for nanosystemsis presented, focusing on the encapsulation of natural products. A five-year literature review is attempted covering the use of chitosan and modified chitosan as matrices and coatings for the encapsulation of natural extracts, essential oils or pure naturally occurring bioactive compounds are discussed.

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“…The complexation of analytes with neutral CDs is mainly motivated by interactions, while electrostatic interactions also contribute when charged CD derivatives are used. In previous studies, the latter was usually chosen based on the analyte's charge [35,36]. In the different formulations, only one molecule was neutral under acidic conditions, while the others were positively charged.…”

Section: Resultsmentioning

confidence: 99%

Determination of antiretroviral drugs for buyers’ club in Switzerland using capillary electrophoresis methods

et al. 2020

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Human immunodeficiency virus‐acquired immunodeficiency syndrome continues to be a major global public health issue, having claimed almost 33 million lives to date. Due to the high cost of antiretroviral treatment, access to these drugs remains difficult for vulnerable populations, such as migrants and people living in prisons, who often do not have health insurance. These factors lead to poorer health outcomes and higher transmission rates. The personal importation scheme for unapproved generics from foreign countries is one option to access affordable human immunodeficiency virus treatment. However, the risk of importing falsified medicine remains high, and the quality control of unapproved drugs is lacking. In this context, three CE methods for the analysis of nine antiviral drugs found in commercial pharmaceutical formulations were evaluated. The selected compounds were emtricitabine, tenofovir disoproxil, tenofovir alafenamide, rilpivirine, efavirenz, raltegravir, dolutegravir, abacavir, and lamivudine. The developed methods were successfully applied to determine the active pharmaceutical ingredients of commercial formulations and unapproved generics. The quality control of unapproved generics by CE is an attractive approach due to its good standard of quality, low cost, ecofriendliness, and ease of implementation.

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A review on thermal analyses of cyclodextrins and cyclodextrin complexes

Cited by 100 publications

References 100 publications

Hydrocortisone/cyclodextrin complex electrospun nanofibers for a fast-dissolving oral drug delivery system

Hydrocortisone/cyclodextrin complex electrospun nanofibers for a fast-dissolving oral drug delivery system

Nanosystems for the Encapsulation of Natural Products: The Case of Chitosan Biopolymer as a Matrix

Determination of antiretroviral drugs for buyers’ club in Switzerland using capillary electrophoresis methods

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