A review on the trends of endophytic fungi bioactivities

OMOMOWO, Iyabo Olunike; AMAO, John Ayobami; ABUBAKAR, Abdulwasiu; OGUNDOLA, Adijat Funke; EZEDIUNO, Louis Odimakaose; BAMIGBOYE, Comfort Olukemi

doi:10.1016/j.sciaf.2023.e01594

Cited by 17 publications

(17 citation statements)

References 80 publications

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“…Endophytes like Colletotrichum, Pseudomonas, Bacillus. Herbaspirillum, Alcaligenes, Streptomyces, Piriformospora indica, Sebacina vermifera , and Penicillium have gained particular interest amongst others because of the propensity to produce phytohormones such as auxins, gibberellins (GA), cytokinins and ethylene that favour improved plant development under harsh conditions ( Burragoni and Jeon, 2021 ), ( Omomowo et al., 2023 ). It has been found that the pestalotiopsis microspore produces pestalotin analogue, a metabolite with gibberellin activity that promotes faster germination ( Li et al., 2018 ).…”

Section: The Mechanism Employed By Endophytes In Plant Growth Promoti...mentioning

confidence: 99%

“…It has been found that the pestalotiopsis microspore produces pestalotin analogue, a metabolite with gibberellin activity that promotes faster germination ( Li et al., 2018 ). Likewise, Cladosporium sphaerospermum , an endophyte of Glycine max, is responsible for the production of gibberellic acid, which is known to encourage the growth of rice and soybean plants ( Omomowo et al., 2023 ).…”

Section: The Mechanism Employed By Endophytes In Plant Growth Promoti...mentioning

confidence: 99%

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Towards further understanding the applications of endophytes: enriched source of bioactive compounds and bio factories for nanoparticles

et al. 2023

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The most significant issues that humans face today include a growing population, an altering climate, an growing reliance on pesticides, the appearance of novel infectious agents, and an accumulation of industrial waste. The production of agricultural goods has also been subject to a great number of significant shifts, often known as agricultural revolutions, which have been influenced by the progression of civilization, technology, and general human advancement. Sustainable measures that can be applied in agriculture, the environment, medicine, and industry are needed to lessen the harmful effects of the aforementioned problems. Endophytes, which might be bacterial or fungal, could be a successful solution. They protect plants and promote growth by producing phytohormones and by providing biotic and abiotic stress tolerance. Endophytes produce the diverse type of bioactive compounds such as alkaloids, saponins, flavonoids, tannins, terpenoids, quinones, chinones, phenolic acids etc. and are known for various therapeutic advantages such as anticancer, antitumor, antidiabetic, antifungal, antiviral, antimicrobial, antimalarial, antioxidant activity. Proteases, pectinases, amylases, cellulases, xylanases, laccases, lipases, and other types of enzymes that are vital for many different industries can also be produced by endophytes. Due to the presence of all these bioactive compounds in endophytes, they have preferred sources for the green synthesis of nanoparticles. This review aims to comprehend the contributions and uses of endophytes in agriculture, medicinal, industrial sectors and bio-nanotechnology with their mechanism of action.

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Section: The Mechanism Employed By Endophytes In Plant Growth Promoti...mentioning

confidence: 99%

Section: The Mechanism Employed By Endophytes In Plant Growth Promoti...mentioning

confidence: 99%

Towards further understanding the applications of endophytes: enriched source of bioactive compounds and bio factories for nanoparticles

et al. 2023

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“…During the process of long-term co-evolution, the endophytic fungi have developed a strong symbiotic relationship with their host plants. Many fungal endophytes can help host plants resist adverse stresses (biotic or abiotic) by bringing beneficial effects on plant photosynthesis, plant hormones, secondary metabolites, the antioxidant defense system, or carbon and nitrogen metabolism ( Chen et al, 2021 ; Mirsam et al, 2021 ; Devi et al, 2023 ; Omomowo et al, 2023 ). Furthermore, the endophytic fungi can benefit their host plants by synthesizing a variety of bioactive enzymes or compounds.…”

Section: Introductionmentioning

confidence: 99%

Endophytic fungi in buckwheat seeds: exploring links with flavonoid accumulation

Zhong,

Niu,

Xiang

et al. 2024

Front. Microbiol.

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Buckwheat is a famous edible and medicinal coarse cereal which contain abundant of bioactive flavonoids, such as rutin. In this study, the composition and diversity of endophytic fungi in eight different buckwheat seeds were analyzed by high-throughput sequencing of ITS rDNA. Results showed that, the fungal sequences reads were allocated to 272 OTUs, of them, 49 OTUs were shared in eight buckwheat seeds. These endophytic fungi could be classified into 6 phyla, 19 classes, 41 orders, 79 families, 119 genera, and 191 species. At genus level, Alternaria sp. was the domain fungal endophyte. Besides, fungal endophytes belonged to the genera of Epicocum, Cladosporium, Botrytis, Filbobasidium, Stemphylium, and Vishniacozyma were highly abundant in buckwheat seeds. The total flavonoids and rutin contents in tartary buckwheat cultivars (CQ, XQ, CH, K2) were much higher than those in common buckwheat cultivars (HT, T2, T4, T8). For tartary buckwheat cultivars, the total flavonoids and rutin contents were ranging from 2.6% to 3.3% and 0.9% to 1.3%, respectively. Accordingly, the tartary buckwheat samples displayed stronger antioxidant activity than the common buckwheat. Spearman correlation heat map analysis was successfully found that certain fungal species from the genera of Alternaria, Botryosphaeria, Colletorichum and Diymella exhibited significant positive correlation with flavonoids contents. Results of this study preliminary revealed the fungi-plant interaction relationship at secondary metabolite level, and could provide novel strategy for increasing the flavonoids accumulation of buckwheat seeds, as well as improving their quality.

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“…In recent decades, endophytic fungi have gained prominence as a rich source of natural compounds with interesting pharmacological activities [ 13 , 14 , 15 ]. Therefore, exploring endophytic fungi that inhabit medicinal plants provides ample opportunities to discover new metabolites with potential bioactivity [ 16 , 17 , 18 , 19 , 20 , 21 , 22 ].…”

Section: Introductionmentioning

confidence: 99%

“…The bioactive substances resulting from the secondary metabolism of these microorganisms directly contribute to the adaptation of species and their survival, and they are often produced in stress situations [ 13 , 24 , 25 ]. Flavonoids, alkaloids, steroids, terpenoids, isocoumarins and phenols are among the classes of substances produced by endophytic fungi that present numerous biological activities such as hormonal, antitumor, cytotoxic, antiviral, immunosuppressive, antiparasitic, antimicrobial and antioxidant activities, among others [ 15 , 21 ].…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial and Antioxidant Activities of Endophytic Fungi Associated with Arrabidaea chica (Bignoniaceae)

Gurgel,

de Melo Pereira,

Garcia

et al. 2023

JoF

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The endophytic fungal community of the Amazonian medicinal plant Arrabidaea chica (Bignoniaceae) was evaluated based on the hypothesis that microbial communities associated with plant species in the Amazon region may produce metabolites with interesting bioactive properties. Therefore, the antimicrobial and antioxidant activities of the fungal extracts were investigated. A total of 107 endophytic fungi were grown in liquid medium and the metabolites were extracted with ethyl acetate. In the screening of fungal extracts for antimicrobial activity, the fungus identified as Botryosphaeria mamane CF2-13 was the most promising, with activity against E. coli, S. epidermidis, P. mirabilis, B. subtilis, S. marcescens, K. pneumoniae, S. enterica, A. brasiliensis, C. albicans, C. tropicalis and, especially, against S. aureus and C. parapsilosis (MIC = 0.312 mg/mL). Screening for antioxidant potential using the DPPH elimination assay showed that the Colletotrichum sp. CG1-7 endophyte extract exhibited potential activity with an EC50 of 11 µg/mL, which is equivalent to quercetin (8 µg/mL). The FRAP method confirmed the antioxidant potential of the fungal extracts. The presence of phenolic compounds and flavonoids in the active extracts was confirmed using TLC. These results indicate that two of the fungi isolated from A. chica exhibit significant antimicrobial and antioxidant potential.

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A review on the trends of endophytic fungi bioactivities

Cited by 17 publications

References 80 publications

Towards further understanding the applications of endophytes: enriched source of bioactive compounds and bio factories for nanoparticles

Towards further understanding the applications of endophytes: enriched source of bioactive compounds and bio factories for nanoparticles

Endophytic fungi in buckwheat seeds: exploring links with flavonoid accumulation

Antimicrobial and Antioxidant Activities of Endophytic Fungi Associated with Arrabidaea chica (Bignoniaceae)

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