A Review on the Recent Progress in Matrix Solid Phase Dispersion

Abstract

Matrix solid phase dispersion (MSPD) has proven to be an efficient sample preparation method for solid, semi-solid, and viscous samples. Applications of MSPD have covered biological, food, and environmental samples, including both organic and inorganic analytes. This review presents an update on the development of MSPD in the period 2015~June 2018. In the first part of this review, we focus on the latest development in MSPD sorbent, including molecularly imprinted polymers, and carbon-based nanomaterials etc. The second part presents the miniaturization of MSPD, discussing the progress in both micro-MSPD and mini-MSPD. The on-line/in-line techniques for improving the automation and sample throughput are also discussed. The final part summarizes the success in the modification of original MSPD procedures.

Optimization of double-vortex-assisted matrix solid-phase dispersion for the rapid determination of paraben preservative residues in leafy vegetables

“…Based on previous studies and our experiences involving indoor dust and biota sample pretreatment using various MSPD techniques, C18, PSA and HLB sorbents have shown good extraction efficiency for polar and hydroxylated micropollutants when used as dispersant/clean-up cosorbent. [13][14][15][16][17] Either methanol or acetonitrile was commonly used as the extracting solvent, and either vortex or ultrasonic was oen employed as an extraction mechanic force to increase the extraction efficiency. 8,10,13,14,16,22 To select the signicant type of variables as listed above (also shown in Table 2), a FMLCD with 2 or 3 non-numeric variables was rst applied for selecting the most signicant factors.…”

“…MSPD has been successfully applied to determine various organic pollutants in animal tissue, aquatic biota, and foodstuff, and these applications have been reviewed by Barker, 12 Capriotti et al, 13,14 and Tu and Chen. 15 Further improving on the efficiency of this method, two simplied procedures for the original MSPD have been also developed. Vortex-assisted MSPD (VA-MSPD) was rst reported by Primel's group, the method that replaced the SPE-column by vortex agitation to eliminate the need for SPE-column packing and elution.…”

Micro Salting-Out Assisted Matrix Solid-Phase Dispersion: A Simple and Fast Sample Preparation Method for the Analysis of Bisphenol Contaminants in Bee Pollen

“…In the past decade, matrix solid-phase dispersion (MSPD) has achieved great progress in the sample preparation of complex samples [ 1 , 2 , 3 , 4 ]. The major merit of MSPD is the accomplishing of extraction and clean-up procedures in one step especially for solid and semi-solid samples [ 5 , 6 ].…”

Determination of Barbiturates in Biological Specimens by Flat Membrane-Based Liquid-Phase Microextraction and Liquid Chromatography-Mass Spectrometry

“…However, it is still difficult to determine the target analyte concentrations at low levels in biological specimens without sample preparation in view of the limited sample volumes and complex sample matrices [8,22,23,24]. Hence, appropriate sample preparation is necessary and of great significance in the whole analysis process.…”