A review on synthesis and biomedical applications of polyglycolic acid

Budak, Kamil; Sogut, Oguz; Sezer, Ümran Aydemir

doi:10.1007/s10965-020-02187-1

Cited by 129 publications

(108 citation statements)

References 129 publications

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“…Their low mechanical stability is also not adequate to support cells, and their products are thus insufficient for the regeneration of tissue. Moreover, the methods for obtaining such materials are limited due to the low resistance of natural polymers to changes in process parameters, such as high temperatures [ 25 , 50 , 51 , 57 , 59 , 64 , 76 , 86 ].Synthetic polymers, such as poly(ethylene glycol) (PEG) [ 87 , 88 ], polycaprolactone (PCL) [ 89 , 90 ], polylactic acid (PLA) [ 87 , 91 , 92 ], polyurethane [ 93 , 94 ], poly(glycolic acid) (PGA) [ 87 , 95 ], polyethersulfone (PES) [ 96 , 97 , 98 , 99 ], and polysulfone [ 100 , 101 ], are more diverse and promising. Some of these materials have been approved by the FDA for clinical human use [ 49 , 51 , 57 , 102 , 103 , 104 , 105 ].…”

Section: Scaffold For Articular Cartilage Repair: Requirements Mamentioning

confidence: 99%

Review of Synthetic and Hybrid Scaffolds in Cartilage Tissue Engineering

2020

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Cartilage tissue is under extensive investigation in tissue engineering and regenerative medicine studies because of its limited regenerative potential. Currently, many scaffolds are undergoing scientific and clinical research. A key for appropriate scaffolding is the assurance of a temporary cellular environment that allows the cells to function as in native tissue. These scaffolds should meet the relevant requirements, including appropriate architecture and physicochemical and biological properties. This is necessary for proper cell growth, which is associated with the adequate regeneration of cartilage. This paper presents a review of the development of scaffolds from synthetic polymers and hybrid materials employed for the engineering of cartilage tissue and regenerative medicine. Initially, general information on articular cartilage and an overview of the clinical strategies for the treatment of cartilage defects are presented. Then, the requirements for scaffolds in regenerative medicine, materials intended for membranes, and methods for obtaining them are briefly described. We also describe the hybrid materials that combine the advantages of both synthetic and natural polymers, which provide better properties for the scaffold. The last part of the article is focused on scaffolds in cartilage tissue engineering that have been confirmed by undergoing preclinical and clinical tests.

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Section: Scaffold For Articular Cartilage Repair: Requirements Mamentioning

confidence: 99%

Review of Synthetic and Hybrid Scaffolds in Cartilage Tissue Engineering

2020

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“…They are biocompatible and can be fully absorbed within 5 months. PGA is the first biomedical synthetic polymer used in clinical medicine, and they have a high degree of crystallinity to make a large tensile elastic modulus as well as excellent mechanical properties ( Budak et al, 2020 ). Therefore, PGA and its derivatives have been employed in medical fields such as drug delivery and dental and orthopedic systems ( Takimoto et al, 2014 ; Sakaguchi et al, 2016 ; Sharma and Sharma 2018 ), and PGA sheets, as a form of tissue engineering scaffold, are widely used in gastrointestinal field.…”

Section: Biomedical Polymersmentioning

confidence: 99%

Recent Advances of Biomedical Materials for Prevention of Post-ESD Esophageal Stricture

Bao

et al. 2021

Front. Bioeng. Biotechnol.

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Esophageal stricture commonly occurs in patients that have suffered from endoscopic submucosal dissection (ESD), and it makes swallowing difficult for patients, significantly reducing their life qualities. So far, the prevention strategies applied in clinical practice for post-ESD esophageal stricture usually bring various inevitable complications, which drastically counteract their effectiveness. Nowadays, with the widespread investigation and application of biomedical materials, lots of novel approaches have been devised in terms of the prevention of esophageal stricture. Biomedical polymers and biomedical-derived materials are the most used biomedical materials to prevent esophageal stricture after ESD. Both of biomedical polymers and biomedical-derived materials possess great physicochemical properties such as biocompatibility and biodegradability. Moreover, some biomedical polymers can be used as scaffolds to promote cell growth, and biomedical-derived materials have biological functions similar to natural organisms, so they are important in tissue engineering. In this review, we have summarized the current approaches for preventing esophageal stricture and put emphasis on the discussion of the roles biomedical polymers and biomedical-derived materials acted in esophageal stricture prevention. Meanwhile, we proposed several potential methods that may be highly rational and feasible in esophageal stricture prevention based on other researches associated with biomedical materials. This review is expected to offer a significant inspiration from biomedical materials to explore more effective, safer, and more economical strategies to manage post-ESD esophageal stricture.

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“…[51,52] Nevertheless, water electrolysis to produce H 2 and O 2 is being scaled up rapidly and is commonly used in power-to-gas (CO 2 methanation using Green H 2 ) applications. [38] Other approaches to valorize CO 2 involve the electrochemical reduction of CO 2 to CO, and the subsequent Fischer-Tropsch (FT) reaction with hydrogen to produce alkanes. [53] The FT process is well-documented and catalysts can be optimized to produce short chain paraffins that can be used for plastic production applications.…”

Section: Plants (Ie Post-combustion Ccs)mentioning

confidence: 99%

“…33 It is interesting to note, there are a plethora of other examples of polymers derived from bio-sourced origin, including for example polyhydroxyalkanoates (PHA), polyglycolic acid, and more that have been reviewed extensively elsewhere. [37,38] These polymers are being researched for utilization in biomedical applications, e.g. sutures or stents.…”

Section: Plants (Ie Post-combustion Ccs)mentioning

confidence: 99%

Towards a Plastic Circular Economy: Bio-derived Plastics and their End-of-life Strategies

Verstraeten

Muyden

Bobbink

2021

Chimia

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Herein, we describe the status of bio-derived plastics as well as the existing and emerging technologies that are available for their post-consumer end-of-life valorization. We first present how bio-derived plastics can be produced from renewable materials such as biomass and CO2. In the second section, we present an overview of the technologies available for the end-of-life, including pyrolysis and gasification and how they can be leveraged towards a circular economy. We continue the discussion with the presentation of an emerging technology, polyolefin hydrocracking. Finally, the concepts are discussed in light of life cycle analysis that helps to assess the sustainability of manufacture (and recycling) methods.

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A review on synthesis and biomedical applications of polyglycolic acid

Cited by 129 publications

References 129 publications

Review of Synthetic and Hybrid Scaffolds in Cartilage Tissue Engineering

Review of Synthetic and Hybrid Scaffolds in Cartilage Tissue Engineering

Recent Advances of Biomedical Materials for Prevention of Post-ESD Esophageal Stricture

Towards a Plastic Circular Economy: Bio-derived Plastics and their End-of-life Strategies

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