A review on chitosan-gelatin nanocomposites: Synthesis, characterization and biomedical applications

Sethi, Sapna; Medha,; Kaith, Balbir Singh

doi:10.1016/j.reactfunctpolym.2022.105362

Cited by 51 publications

(14 citation statements)

References 92 publications

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“…The network distortion can also be confirmed by changing the position of the peak’s characteristic of C-H bonds (up to 3077, 2919 and 2873

). The interaction between the silver nanoparticles and the components of the hydrogel is supported by the shift of the bands that can be associated with the C–O bonds from the carboxyl group (up to 1398, 1197, 1156 and 1030

), as well as by the lack of spectral bands below 900

[ 37 , 40 , 41 , 42 , 43 , 44 ].…”

Section: Resultsmentioning

confidence: 99%

The Physicochemical and Antimicrobial Properties of Silver/Gold Nanoparticles Obtained by “Green Synthesis” from Willow Bark and Their Formulations as Potential Innovative Pharmaceutical Substances

et al. 2022

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Green chemistry is a pharmaceutical industry tool, which, when implemented correctly, can lead to a minimization in resource consumption and waste. An aqueous extract of Salix alba L. was employed for the efficient and rapid synthesis of silver/gold particle nanostructures via an inexpensive, nontoxic and eco-friendly procedure. The nanoparticles were physicochemically characterized using ultraviolet–visible spectroscopy (UV–Vis), Fourier transform infrared spectroscopy (FT-IR), dynamic light scattering (DLS), X-ray diffraction (XRD) and scanning electron microscopy (SEM), with the best stability of up to one year in the solution obtained for silver nanoparticles without any chemical additives. A comparison of the antimicrobial effect of silver/gold nanoparticles and their formulations (hydrogels, ointments, aqueous solutions) showed that both metallic nanoparticles have antibacterial and antibiofilm effects, with silver-based hydrogels having particularly high antibiofilm efficiency. The highest antibacterial and antibiofilm efficacies were obtained against Pseudomonas aeruginosa when using silver nanoparticle hydrogels, with antibiofilm efficacies of over 75% registered. The hydrogels incorporating green nanoparticles displayed a 200% increased bacterial efficiency when compared to the controls and their components. All silver nanoparticle formulations were ecologically obtained by “green synthesis” and were shown to have an antimicrobial effect or potential as keratinocyte-acting pharmaceutical substances for ameliorating infectious psoriasis wounds.

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“…The network distortion can also be confirmed by changing the position of the peak’s characteristic of C-H bonds (up to 3077, 2919 and 2873

), as well as by the lack of spectral bands below 900

[ 37 , 40 , 41 , 42 , 43 , 44 ].…”

Section: Resultsmentioning

confidence: 99%

The Physicochemical and Antimicrobial Properties of Silver/Gold Nanoparticles Obtained by “Green Synthesis” from Willow Bark and Their Formulations as Potential Innovative Pharmaceutical Substances

et al. 2022

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“…Several studies reported that mixing chitosan and gelatin could improve the limitations of chitosan and gelatin if used as a single material [ 28 , 29 , 30 , 31 , 32 , 33 ]. Furthermore, the association of chitosan and gelatin, when loaded by nanoparticles, for instance, bioactive nanoparticle material, could form nanocomposites that enhance biocompatibility, hemostatic potential, and bioactivity, that are suitable candidates for biomedical application, including hemostatic agents [ 21 ].…”

Section: Discussionmentioning

confidence: 99%

“…The combination of two materials with different physical, chemical and mechanical properties to form a new material with superior properties and characteristics is called a composite material [ 17 ]. The application of chitosan-gelatin (CG) composite-based biomaterials has been widely used as a local hemostatic agent and in other biomedical fields and food packaging processes [ 18 , 19 , 20 , 21 , 22 ]. For example, Ali et al reported a study about antimicrobial and wound-healing activities of graphene-reinforced electrospun chitosan/gelatin nanofibrous nanocomposite scaffolds [ 23 ].…”

Section: Introductionmentioning

confidence: 99%

“…Aside from acting as a matrix for dispersing nanoparticles, the CG composite can also act as a reducing and stabilizing agent for nanoparticles to prevent agglomeration. Chitosan and gelatin are frequently mixed to enhance the biological features of the material produced by stimulating cell attachment and the development of a polyelectrolyte complex [ 21 ].…”

Section: Introductionmentioning

confidence: 99%

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Characterization and Analysis of Chitosan-Gelatin Composite-Based Biomaterial Effectivity as Local Hemostatic Agent: A Systematic Review

et al. 2023

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Chitosan and gelatin were the most widely used natural materials in pharmaceutical and medical fields, especially as local hemostatic agents, independently or as a composite material with the addition of other active substances. Chitosan and gelatin have excellent properties in biocompatibility, biodegradability, non-toxicity and water absorption capacity. The objective of this review was to analyze the characteristics of chitosan-gelatin (CG) composite-based biomaterial and its effectivity as a local hemostatic agent. We used PRISMA guidelines and the PICO framework to compile this review. The findings demonstrated that the CG composite-based biomaterial had excellent physical, chemical, mechanical properties and local hemostatic agent activity by adding other active substances such as oxidized fibers (OF), silica nanoparticles (SiNPs), calcium (Ca) and biphasic calcium phosphate (BCP) or by setting the CG composite proportion ratio.

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“…In publications, numerous studies are described on the use of chitosan as an OP sorbent in case of oil spills on soil, water surface, and for wastewater treatment [29][30][31]. However, chitosan has a high cost, a complex production process, and is in demand in more high-tech branches of medicine and food industry [32,33]. Due to economic reasons, it is rarely used on an industrial scale as a sorption material for oil spill response.…”

mentioning

confidence: 99%

Evaluation of the efficiency of sorbents for accidental oil spill response in the Arctic waters

Vasilyeva

Vasekha

Tyulyaev

2023

PMI

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The development and operation of new oil fields on the Arctic shelf increases the risks of oil spills, which require the use of oil spill response tools and materials that are efficient in harsh climatic conditions. The question of actual efficiency of sorbents for reducing the level of oil pollution in the conditions of the Arctic and subarctic waters is relevant. The work is aimed at a comparative study of the efficiency of sorbents of mineral and organic origin used by coastal enterprises in the Kola Bay as well as a sorbent based on chitin in model systems simulating real conditions in sea waters. The characteristics of sorption agents were determined applying ASTM F716-18 procedure. Sorption capacity was evaluated in respect of ARCO grade oil, diesel fuel and marine oil. The efficiency of sorbents was estimated in model systems “sea water – oil” at water temperature corresponding to the average annual surface temperature in the Barents Sea. Actual data on sorption capacity of commercial sorbents “Lessorb”, “Novosorb”, a sorbent based on vermiculite and chitin sorbent in relation to potential pollutants of waters were obtained. The dynamics of sea water saturation with oil products at –0.5 (±1) and 10 (±1) °С was determined. It is shown that at higher temperature the concentration of oil products in sea water column (in the presence of an oil film on the surface) is on average four times higher than at low temperature. Kinetic dependences were obtained that describe the content of oil products in water column and near-surface layer of sea water in the presence of the studied sorbents at 5 (±1) °C, corresponding to the average annual temperature in the Kola Bay of the Barents Sea. A method is proposed for evaluating the efficiency of sorbents from the values of regression coefficients characterizing the dependence of oil products content in sea water on the character of sorbent and duration of its action.

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A review on chitosan-gelatin nanocomposites: Synthesis, characterization and biomedical applications

Cited by 51 publications

References 92 publications

The Physicochemical and Antimicrobial Properties of Silver/Gold Nanoparticles Obtained by “Green Synthesis” from Willow Bark and Their Formulations as Potential Innovative Pharmaceutical Substances

The Physicochemical and Antimicrobial Properties of Silver/Gold Nanoparticles Obtained by “Green Synthesis” from Willow Bark and Their Formulations as Potential Innovative Pharmaceutical Substances

Characterization and Analysis of Chitosan-Gelatin Composite-Based Biomaterial Effectivity as Local Hemostatic Agent: A Systematic Review

Evaluation of the efficiency of sorbents for accidental oil spill response in the Arctic waters

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