A Review on Antiulcer Activity of Few Indian Medicinal Plants

Abstract

Ulcer is a common gastrointestinal disorder which is seen among many people. It is basically an inflamed break in the skin or the mucus membrane lining the alimentary tract. Ulceration occurs when there is a disturbance of the normal equilibrium caused by either enhanced aggression or diminished mucosal resistance. It may be due to the regular usage of drugs, irregular food habits, stress, and so forth. Peptic ulcers are a broad term that includes ulcers of digestive tract in the stomach or the duodenum. The formation of peptic ulcers depends on the presence of acid and peptic activity in gastric juice plus a breakdown in mucosal defenses. A number of synthetic drugs are available to treat ulcers. But these drugs are expensive and are likely to produce more side effects when compared to herbal medicines. The literature revealed that many medicinal plants and polyherbal formulations are used for the treatment of ulcer by various ayurvedic doctors and traditional medicinal practitioners. The ideal aims of treatment of peptic ulcer disease are to relieve pain, heal the ulcer, and delay ulcer recurrence. In this review attempts have been made to know about some medicinal plants which may be used in ayurvedic as well as modern science for the treatment or prevention of peptic ulcer.

Ethnobotanical study of medicinal plants by population of Valley of Juruena Region, Legal Amazon, Mato Grosso, Brazil

“…The in vitro and in vivo pharmacological, biochemical, and clinical studies carried out on the extracts, and the main active constituents isolated from Phyllanthus niruri (Vimala and Gricilda Shoba, 2014;Bieski et al, 2012;Boim et al, 2010;Bagalkotkar et al, 2006;Murugaiyah and Chan, 2006;). …”

The Purview of Phytotherapy in the Management of Gastric Ulcer

“…While Table 1 also presents some of these phytonutrients as being responsible for the elicited antiulcerogenic properties of the plants, several others have also been identified and isolated from diverse plants. Some of these include; saponins, phobaphenes, glucose, luvangetin, tartarate, potash, nimbidin, quercetin, apigenin, papain, chymopapain, pectin, carposide, carotenoids, antheraxanthin, carpaine, resin, euphorbon, caoutchouc, rutin, anthocyanins, cyanindin, kaempferol, sterols, mucilage, terpenoids, kaepferom, ash, starch, fats, proteins, glycosides, ellagic acid, beta sitosterol, gallic acid, limonene, pinene, albuminous matter, cellulose, chlorophyll, mineral salts, myricitin, triterpenes, and sorbitol [37]. These compounds have either been elucidated to decrease acid/pepsin secretion or confer cytoprotection via effective modulation on mucosal defensive factors.…”

Evaluation of Chemical Properties and Mineral Composition of Powdered and Dried Leaves of Baobab in Bauchi Metropolis

“…It refers to a group of trees that are grown in tropical and sub-tropical regions of the hemisphere especially, in the Madagascar. It is probably the best know tree in Africa (Vimala, Shoba, 2014). Its thick, grey, fibrous trunk reaching in some instances over 25cm and the large spreading crown seasonally devoid of foliage, are instantly recognizable.…”

“…The flowers and fruit hang from the stem which is long-tongue, hawk moths.The flowers and fruit hang from the stem which is long and ropy. The fruit with a hard woody shell covered in yellowish green velvety hair are again easily identified inside the shell the fruit containing a number of seeds, embedded in a whitish, powdery pulp and nutrients the pulp makes a tasty food after soaking in water or milk to make a refreshing beverage (Walker, 2014).…”

“…The fruit which grows up to a foot long, contain tartanic acid and vitamin ca and can neither be sucked or soaked in water to make a refreshing drink (Vimala, Shoba, 2014). Fresh baobab leaves provide an edible vegetable similar to spinach which is also used medicinally to treat kidney and bladder disease, asthma, insect bites and several other maladies.…”