A review of zeta potential measurements using electroacoustics

Mohammadi-Jam, Shiva; Waters, Kristian E.; Greenwood, R.

doi:10.1016/j.cis.2022.102778

Cited by 33 publications

(18 citation statements)

References 289 publications

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“…The nanoscale size suggested that the nanoparticles we prepared possessed the potential to serve as an ideal nanocarrier for they are suitable for passive tumor penetration and accumulation via the EPR effect. Apart from size, the zeta potential is another major parameter that affects the stability of the nanoparticles. , The measured zeta potential of DTX@NPs was −26.6 ± 0.9 mV (Figure H), indicating good stability. Additionally, after being stored in different media including PBS (pH 7.4, pH 6.8, and pH 5.5), FBS, and RPMI 1640 supplemented with 10% FBS for seven consecutive days, the D h of DTX@NPs remained relatively stable (Figures I,J), further demonstrating the excellent stability of the DTX@NPs.…”

Section: Resultsmentioning

confidence: 99%

Glutathione and Esterase Dual-Responsive Smart Nano-drug Delivery System Capable of Breaking the Redox Balance for Enhanced Tumor Therapy

Shen

Zhang

Ding

et al. 2023

ACS Appl. Mater. Interfaces

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Conventional chemotherapy usually fails to achieve its intended effect because of the poor water solubility, poor tumor selectivity, and low tumor accumulation of chemotherapy drugs. The systemic toxicity of chemotherapy agents is also a problem that cannot be ignored. It is expected that smart nano-drug delivery systems that are able to respond to tumor microenvironments will provide better therapeutic outcomes with decreased side effects of chemotherapeutics. Nano-drug delivery systems capable of breaking the redox balance can also increase the sensitivity of tumor cells to chemotherapeutics. In this study, using polymer-containing disulfide bonds, ester bonds, and d-α-tocopherol polyethylene glycol succinate (TPGS), which can amplify reactive oxygen species (ROS) in tumor cells, we have successfully prepared a smart glutathione (GSH) and esterase dual-responsive nano-drug delivery system (DTX@PAMBE-SS-TPGS NPs) with the ability to deplete GSH as well as amplify ROS and effectively release an encapsulated chemotherapy drug (DTX) in tumor cells. The potential of DTX@PAMBE-SS-TPGS NPs for enhanced antitumor effects was thoroughly evaluated using in vitro as well as in vivo experiments. Our research offers a promising strategy for maximizing the efficacy of tumor therapy.

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Section: Resultsmentioning

confidence: 99%

Glutathione and Esterase Dual-Responsive Smart Nano-drug Delivery System Capable of Breaking the Redox Balance for Enhanced Tumor Therapy

Shen

Zhang

Ding

et al. 2023

ACS Appl. Mater. Interfaces

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“…The ζ-potential was studied by acoustic and electroacoustic spectroscopy at the DT-1202 facility (Dispersion Technology, New York, NY, USA) [ 34 ].…”

Section: Methodsmentioning

confidence: 99%

Investigation of the Effect of Dispersion Medium Parameters on the Aggregative Stability of Selenium Nanoparticles Stabilized with Catamine AB

et al. 2023

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This article presents the results of the synthesis of Se NPs stabilized by a quaternary ammonium compound—catamine AB. Se NPs were obtained by chemical reduction in an aqueous medium. In the first stage of this study, the method of synthesis of Se NPs was optimized by a multifactorial experiment. The radius of the obtained samples was studied by dynamic light scattering, and the electrokinetic potential was studied using acoustic and electroacoustic spectrometry. Subsequently, the samples were studied by transmission electron microscopy, and the analysis of the data showed that a bimodal distribution is observed in negatively charged particles, where one fraction is represented by spheres with a diameter of 45 nm, and the second by 1 to 10 nm. In turn, positive Se NPs have a diameter of about 70 nm. In the next stage, the influence of the active acidity of the medium on the stability of Se NPs was studied. An analysis of the obtained data showed that both sols of Se NPs exhibit aggregative stability in the pH range from 2 to 6, while an increase in pH to an alkaline medium is accompanied by a loss of particle stability. Next, we studied the effect of ionic strength on the aggregative stability of Se NPs sols. It was found that negatively charged ions have a significant effect on the particle size of the positive sol of Se NPs, while the particle size of the negative sol is affected by positively charged ions.

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“…The colloid vibration potential (CVP) and electrokinetic sonic amplitude (ESA) are collectively known as electroacoustic effects. − Note that the electroacoustic phenomena find their potential applications to quantify various physicochemical properties of dispersed colloidal systems, including the size and electrostatic charge properties of the charged macromolecules. ,− When an alternating current is applied to a suspension of charged colloidal entities immersed in electrolyte solution, the back-and-forth motion of colloids induces the sound wave, which is often termed as ESA . On the other hand, a sound wave generates an alternating electric field and induces the CVP. , Note that the ESA and CVP phenomena are related to each other, and these effects are certainly linked via the dynamic electrophoretic mobility of the suspension .…”

Section: Introductionmentioning

confidence: 99%

“…The evaluation of surface ζ-potential for colloidal entities cannot be done directly . The same is often done by comparing the theoretical results to the corresponding experimentally measured parameters of colloidal suspensions .…”

Section: Introductionmentioning

confidence: 99%

“…14 The evaluation of surface ζ-potential for colloidal entities cannot be done directly. 9 The same is often done by comparing the theoretical results to the corresponding experimentally measured parameters of colloidal suspensions. 15 The determination of the ζ-potential for concentrated colloidal dispersion is difficult by using the light-scattering method because the sample is not transparent for such a case.…”

Section: Introductionmentioning

confidence: 99%

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Dynamic Electrophoresis of a Hydrophobic and Dielectric Fluid Droplet

Chowdhury,

Mahapatra,

Ohshima

et al. 2023

Langmuir

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Dynamic electrophoresis is the foundation for electroacoustical measurements, in which the electroacoustical signals may be used to analyze the size and electrostatic charge of colloidal entities by means of the results for dynamic electrophoretic mobility. Thus, the electrophoresis under an alternating electric field is the key foundation for electroacoustic theory. In this article, we develop a tractable analytical theory for the dynamic electrophoresis of hydrophobic and dielectric fluid droplets possessing uniform surface charge density. The tiny fluid droplets possess charged mobile surfaces and have found widespread applications in our day-to-day life. For dielectric fluid droplets (e.g., oil–water emulsions), the tangential electric stress at the interface is nonzero, which significantly affects its electrohydrodynamics under an oscillatory electric field, which has, however, a negligible impact on the electrophoretic motion of conducting droplets (e.g., mercury droplets). Besides, the micro/nanoscale fluid droplets often show hydrophobicity when they are immersed in an aqueous medium, and the impact of the electric field on hydrophobic surfaces remains a research frontier in the chemical discipline. Whereas a number of approximate expressions for electrophoretic mobility have been derived for the conducting droplet, none of them are applicable to such generic hydrophobic fluid droplets with dielectric permittivity that is significantly lower than or comparable to that of an aqueous medium. In this work, within the Debye–Hückel electrostatic framework, we elaborate an original analytical expression of dynamic electrophoretic mobility for this generic dielectric fluid droplet with a hydrophobic surface considering that the droplet retains its spherical shape during its oscillatory motion. We further derived a set of simplified expressions for dynamic electrophoretic mobility deduced under several limiting cases. The results are further illustrated, indicating the impact of pertinent parameters.

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A review of zeta potential measurements using electroacoustics

Cited by 33 publications

References 289 publications

Glutathione and Esterase Dual-Responsive Smart Nano-drug Delivery System Capable of Breaking the Redox Balance for Enhanced Tumor Therapy

Glutathione and Esterase Dual-Responsive Smart Nano-drug Delivery System Capable of Breaking the Redox Balance for Enhanced Tumor Therapy

Investigation of the Effect of Dispersion Medium Parameters on the Aggregative Stability of Selenium Nanoparticles Stabilized with Catamine AB

Dynamic Electrophoresis of a Hydrophobic and Dielectric Fluid Droplet

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