Investigation of the Effect of Dispersion Medium Parameters on the Aggregative Stability of Selenium Nanoparticles Stabilized with Catamine AB

Abstract

This article presents the results of the synthesis of Se NPs stabilized by a quaternary ammonium compound—catamine AB. Se NPs were obtained by chemical reduction in an aqueous medium. In the first stage of this study, the method of synthesis of Se NPs was optimized by a multifactorial experiment. The radius of the obtained samples was studied by dynamic light scattering, and the electrokinetic potential was studied using acoustic and electroacoustic spectrometry. Subsequently, the samples were studied by transmission electron microscopy, and the analysis of the data showed that a bimodal distribution is observed in negatively charged particles, where one fraction is represented by spheres with a diameter of 45 nm, and the second by 1 to 10 nm. In turn, positive Se NPs have a diameter of about 70 nm. In the next stage, the influence of the active acidity of the medium on the stability of Se NPs was studied. An analysis of the obtained data showed that both sols of Se NPs exhibit aggregative stability in the pH range from 2 to 6, while an increase in pH to an alkaline medium is accompanied by a loss of particle stability. Next, we studied the effect of ionic strength on the aggregative stability of Se NPs sols. It was found that negatively charged ions have a significant effect on the particle size of the positive sol of Se NPs, while the particle size of the negative sol is affected by positively charged ions.

Application of the Se NPs-Chitosan molecular complex for the correction of selenium deficiency in rats model

“…According to previous studies, the effect of the selenium: polysaccharide mass ratio was determined by the saturation region of the adsorption capacity, which affects the formation process and morphological characteristics of nanostructures [29], [32]. According to UV spectroscopy, viscometry and pHmetre, this region corresponds to a range of mass ratios (v) from 0.02 to 0.08 [33]. In this work, a selenium nanocomposite with a mass ratio of v = 0.04 was used, a selenium nanocomposite with a mass ratio of v = 0.04 was used The X-ray diffraction pattern showed the presence of peaks characteristic of polycrystalline selenium [34].…”

Synthesis, Characterization and Potential Antimicrobial Activity of Selenium Nanoparticles Stabilized with Cetyltrimethylammonium Chloride

“…It was found that at pH 10, a large loss of aggregation stability of the positive Se NP sol was observed, which is confirmed by the decrease in ζ-potential at these pH values. At 5 < pH < 8, an increase in particle size of the positive Se NP sol was again observed, probably because the isoelectric point of CTAC was reached [57]. For negative Se NPs sols, increasing pH does not affect aggregate stability, indicating high stability across the studied range [62,63].…”

“…Quantum chemical computer modeling results show that the total energy of the CTAC molecule is −803.904 kcal/mol, and the energy of the Se-CTAC molecular complex is −12,795.691 kcal/mol. A decrease in the total energy of the system indicates the energetic advantage of chemical bond formation between Se and CTAC [57].…”