A review of the literature on the effects of ambient air pollution on fetal growth

Maisonet, Mildred; Correa, Adolfo; Misra, Dawn P.; Jaakkola, Jouni J. K.

doi:10.1016/j.envres.2004.01.001

Cited by 275 publications

(198 citation statements)

References 19 publications

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“…The possible biological mechanisms of air pollution on birth weight might vary according the time of pregnancy, such as the implantation of the fetus and the formation of placenta during the first trimester, as well as important weight gain during the third trimester. Placental abnormalities, DNA damage, disruption of the endocrine system and change of blood coagulability are those potential biological mechanisms, which have been reported (Dejmek et al, 2000;Maisonet et al, 2004;Perera et al, 1999Perera et al, , 2002Whyatt et al, 1998). The finding of a significant effect of PM exposure on LBW during the first trimester is consistent.…”

Section: Window Periodssupporting

confidence: 78%

Air Pollution and Adverse Pregnancy Outcome

Leem¹,

Ha²

2011

Air Pollution - New Developments

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Section: Window Periodssupporting

confidence: 78%

Air Pollution and Adverse Pregnancy Outcome

Leem¹,

Ha²

2011

Air Pollution - New Developments

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“…Nevertheless, there are a growing number of contemporary studies that have evaluated potential links between air pollution and birth weight, [445][446][447][448][449][450][451][452][453][454][455][456] premature birth, 449,456 -458 fetal growth, 459 -461 intrauterine mortality, 462 birth defects, 463 and lymphocyte immunophenotypes in cord and maternal blood at delivery. 464 Recent reviews of the literature dealing with air pollution and these various birth outcomes 441,442,444 generally suggest that there may be effects of ambient PM air pollution on these outcomes but that these effects are not well understood. Although the evidence is reasonably compelling that PM exposure increases the risk of infant mortality, especially postneonatal respiratory mortality, there remain serious gaps in our knowledge regarding the potential effects of ambient PM on fetal growth, premature birth, and related birth outcomes.…”

Section: Infant/birth Outcomesmentioning

confidence: 99%

Health Effects of Fine Particulate Air Pollution: Lines that Connect

Pope

Dockery²

2006

Journal of the Air & Waste Management Association

5,598

3,159

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Efforts to understand and mitigate the health effects of particulate matter (PM) air pollution have a rich and interesting history. This review focuses on six substantial lines of research that have been pursued since 1997 that have helped elucidate our understanding about the effects of PM on human health. There has been substantial progress in the evaluation of PM health effects at different time-scales of exposure and in the exploration of the shape of the concentration-response function. There has also been emerging evidence of PM-related cardiovascular health effects and growing knowledge regarding interconnected general pathophysiological pathways that link PM exposure with cardiopulmonary morbidity and mortality. Despite important gaps in scientific knowledge and continued reasons for some skepticism, a comprehensive evaluation of the research findings provides persuasive evidence that exposure to fine particulate air pollution has adverse effects on cardiopulmonary health. Although much of this research has been motivated by environmental public health policy, these results have important scientific, medical, and public health implications that are broader than debates over legally mandated air quality standards.

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“…Risk for acute events, including myocardial infarction and stroke, has been assessed [7]. Risk for birth outcomes has also been studied, but the evidence is still inconclusive based on the currently available data [8,9].…”

Section: Pmmentioning

confidence: 99%