2019
DOI: 10.3390/bios9010046
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A Review of the Construction of Nano-Hybrids for Electrochemical Biosensing of Glucose

Abstract: Continuous progress in the domain of nano and material science has led to modulation ofthe properties of nanomaterials in a controlled and desired fashion. In this sense, nanomaterials,including carbon-based materials, metals and metal oxides, and composite/hybrid materials haveattracted extensive interest with regard to the construction of electrochemical biosensors. Themodification of a working electrode with a combination of two or three nanomaterials in the formof nano-composite/nano-hybrids has revealed g… Show more

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Cited by 85 publications
(54 citation statements)
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“…Another common type of electrochemical biosensor uses amperometric/voltammetric transducers in which the produced current by the potential difference between electrodes and the analyte contributes to a redox reaction [ 69 , 70 ]. Karyakin et al developed an enzyme-based amperometric biosensor which transduces the oxidation of glutamate through Prussian Blue that selectively senses the reduction of the H 2 O 2.…”
Section: Classification Of Biosensorsmentioning
confidence: 99%
“…Another common type of electrochemical biosensor uses amperometric/voltammetric transducers in which the produced current by the potential difference between electrodes and the analyte contributes to a redox reaction [ 69 , 70 ]. Karyakin et al developed an enzyme-based amperometric biosensor which transduces the oxidation of glutamate through Prussian Blue that selectively senses the reduction of the H 2 O 2.…”
Section: Classification Of Biosensorsmentioning
confidence: 99%
“…The analytical performances in terms of high sensitivity, wide linear range and low detection limit of some of the reviewed biosensors evidence that these systems have the potential to radically change food analysis. However, despite the variety of electrochemical biosensors for glucose and lactate monitoring, 35,[115][116][117][118][119][120][121][122][123][124][125] limited number of devices successfully applied for quality and safety assessment of foods and beverages testifies that the food sample matrices present significant challenges and there is still a need to improve analytical performances, both selectivity and operational stability of the immobilised biocomponent and shelf-life of biosensor systems. Moreover, designing novel reliable and commercially available biosensors that are capable to detect nanomolar levels of analytes, as well as biosensors for reliable analysis of multiple analytes using a single device, 126,127 are required in the field of food industry and have become an important topic in electroanalysis.…”
Section: Discussionmentioning
confidence: 99%
“…Electrochemical biosensors can convert biological information into a measurable electrical signal using simple electronics for conditioning and read-out [128]. These biosensors are advantageous in terms of linear output, excellent repeatability, reliable, portable, accurate, and require less power [129]. On the other hand, the shelf-life, stability of biorecognition element, non-specific binding, and ultra-sensitivity to temperature are the limitations of electrochemical biosensors [130].…”
Section: Electrochemical Biosensorsmentioning
confidence: 99%