A review of surface-enhanced Raman spectroscopy in pathological processes

Nanomaterial-based surface-enhanced Raman scattering spectroscopy for sensing and diagnostics of gas molecules in environment and healthcare

“…It is to be noted that a few reviews seem to be similar but these are entirely different because all are focused on a particular theme, either on healthcare (mainly on a particular disease or materials) or environment related (on a particular problem). [73][74][75][76][77][78] The proposed article is focused on environmental and healthcare applications, including the pandemic COVID-19 problem and scientific solutions with a potential for commercialization because of its portability and simple handling as compared to the traditional sensor/biosensors/environmental sensors. This is an emerging research area where various plasmonic based nanomaterials and SERS technique could be potentially applied for the analysis of the human breath to monitor human health as well as for the detection of such gases in environmental monitoring, as shown schematically in Fig.…”

“…Furthermore, its applications in environmental control and healthcare have been explored. It is to be noted that there are a few reviews seems to be similar but these are entirely different because all are focused on a particular theme either on healthcare (mainly on a particular disease or materials) or environment related (on a particular problem) [73][74][75][76][77][78]. The proposed article is focused on the environmental and healthcare applications including the pandemic COVID-19 problem and solution with potential of commercialization scientific solution because of its portability and simple handling ability as compared to the traditional sensor/biosensors/environmental sensors.…”

Use of Raman spectroscopy to study rat lung tissues for distinguishing asphyxia from sudden cardiac death

“…22,23 Raman spectroscopy can examine subtle biochemical alterations in certain pathophysiological mechanisms to diagnose associated diseases. 24,25 Infrared spectroscopy, another vibrational spectroscopy technique complementary to Raman spectroscopy, is also widely used in forensic research to identify injuries, histopathological changes, 26,27 and determine the cause of death. 28,29 In addition, the technical advantages of Raman spectroscopy make it more suitable for forensic practice than other molecular biological techniques.…”

Raman spectroscopy as a promising diagnostic method for rheumatoid arthritis

“…Raman spectroscopy is a label-free, real-time, and nonperturbative optical method that can reveal the molecular vibrational motions and rotational information. [5][6][7] Based on the inelastic scattering of light and energy exchange, Raman spectroscopy provides biochemical information on the composition of a given sample. So far, Raman spectroscopy has been used to study cells, tissues, liquid biopsies, and even in vivo cancer detection schemes.…”