A review of penile metastasis

Abstract

Penile cancer as primary disease is relatively rare in developed countries. The penis is a rare site of metastases in spite of its rich vascularization. Approximately 500 cases have been reported in the literature; almost 70% of primary lesions are of pelvic origin (from genitourinary or recto-sigmoid primary tumors). We describe a case of penile metastasis from lung cancer. The rarity of the event prompted us to also explore related reviews and discuss the incidence, physiopathology, diagnosis and therapy of penile secondary cancer.

Penile masses: Shear Wave Elastography correlated with Magnetic Resonance Imagining. A two cases report.

“…Since almost all penile primary cancers start in the skin cells of the penis, early diagnosis of primary cancers is usually not a challenging entity for clinicians. However, secondary penile cancer is usually a deep disease that does not develop as a superficial skin lesion and usually early diagnosis is more difficult [5]. Penile fracture on the other hand is a urological emergency caused by blunt trauma to the penis during erection.…”

“…Secondary penile cancer, as a result of systemic metastasis is a rare condition and is usually secondary to malignancies of the pelvic region [5]. Bladder and prostate are the most common primary organs of penile metastasis [5]. Since almost all penile primary cancers start in the skin cells of the penis, early diagnosis of primary cancers is usually not a challenging entity for clinicians.…”

“…Penile cancer is an uncommon disease and most of them are primary squamous carcinomas [5]. Secondary penile cancer, as a result of systemic metastasis is a rare condition and is usually secondary to malignancies of the pelvic region [5].…”

“…Secondary penile cancer, as a result of systemic metastasis is a rare condition and is usually secondary to malignancies of the pelvic region [5]. Bladder and prostate are the most common primary organs of penile metastasis [5].…”

Penile Metastasis as the First Manifestation of Sarcomatoid Renal Cell Carcinoma

“…Penile nodules involve both corpora cavernosa in about 70% of patients which explains the increased frequency of priapism. Corpus spongiosum and the glans penis are less frequently involved (1). Penile metastasis is associated with advanced disease and, therefore, has a poor prognosis with a short life expectancy (5).…”