A Review of Mixed Connective Tissue Disease

Chubick, Andrew; Gilliam, James N.

doi:10.1111/j.1365-4362.1978.tb06121.x

Cited by 13 publications

(2 citation statements)

References 40 publications

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“…The patients are usually women in the second or third decade of life. Cutaneous findings in MCTD consist of sclerodactyly with puffy, sausage-like swelling of the digits (75% of the cases), 43 nonscarring diffuse alopecia, sclerodermoid nailfold capillaropathy, heliotrope eyelids, Gottron papules, and Raynaud phenomenon. The latter can produce "ice-pick" digital infarcts and gangrene.…”

Section: Mixed Connective Tissue Diseasementioning

confidence: 98%

Dermatopathologic Manifestations of Rheumatologic Diseases

Selim¹,

Shea²

2004

Pathology Case Reviews

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Rheumatologic disorders are multisystem diseases that frequently affect the skin. Cutaneous manifestations may be the gateway to an early diagnosis and accurate classification. This article reviews the histologic findings and differential diagnosis of cutaneous lesions occurring in several rheumatologic disorders including lupus erythematosus, dermatomyositis, scleroderma, and miscellaneous disorders.

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Section: Mixed Connective Tissue Diseasementioning

confidence: 98%

Dermatopathologic Manifestations of Rheumatologic Diseases

Selim¹,

Shea²

2004

Pathology Case Reviews

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“…In the past several years, the concept of an apparently distinct clinical entity referred to as mixed connective tissue disease (MCTD) has been advanced (1,2). This disorder is characterized by overlapping features of systemic lupus erythematosus (SLE), progressive systemic sclerosis (PSS) and polymyositis (PM).…”

mentioning

confidence: 99%

Mixed Connective Tissue Disease

Miyagawa

Iioka

et al. 1980

The Journal of Dermatology

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Myocarditis in mixed connective tissue disease

Whitlow¹,

Gilliam²,

Chubick³

et al. 1980

Arthritis & Rheumatism

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A young black woman with clinical and serologic features of mixed connective tissue disease (MCTD) developed myocarditis with congestive heart failure and ventricular ectopic activity. Despite treatment with steroids and cyclophosphamide, progressive myocarditis resulted in death 20 months after cardiomegaly first developed. Necropsy findings in the myocardium included multiple areas of extensive lymphocytic infiltration and patches of fibrosis. Myocarditis has not previously been described in the adult with MCTD but may be an important complication in patients with a high titer of antibody to nuclear ribonucleoprotein.

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A Review of Mixed Connective Tissue Disease

Cited by 13 publications

References 40 publications

Dermatopathologic Manifestations of Rheumatologic Diseases

Dermatopathologic Manifestations of Rheumatologic Diseases

Mixed Connective Tissue Disease

Myocarditis in mixed connective tissue disease

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