A Review of Infantile Acrodynia ('Pink Disease')

Ancestry of Pink Disease (Infantile Acrodynia) Identified as a Risk Factor for Autism Spectrum Disorders

“…Case studies provided a comprehensive clinical picture of pink disease long before its etiology was established. The most commonly reported symptoms included: irritability, neurosis, photophobia (light sensitivity), hyperhidrosis (excessive sweating), hypotonia (low muscle tone), ataxia (lack of coordination), digestive problems (including loss of weight, loss of appetite, vomiting, and constipation), anemia, excessive salivation, respiratory problems, lethargy, extreme misery, slurring/lossof speech, loosening/loss of teeth, swollen extremities, and perhaps most famously (and from which the name “pink disease” was derived), marked reddening of the extremities, particularly the hands and feet ( Rocaz 1933 ; Wood and Wood 1935 ; Leys 1950 ). Fatality was reasonably high, with death resulting in 10–33% of cases ( Rocaz 1933 ).…”

Annotations

“…PROSTITUTION MEDICJOURNL found that 5% of 400 girls examined in a remand home for juveniles aged [14][15][16][17] were prostitutes at the time of their arrest, and another 5% of 200 who were followed up took to prostitution in the next few years. Nearly all the girls were sexually experienced or promiscuous and often " on the run."…”