A review of fatty acids influencing skin condition

Yang, Meifang; Zhou, Mingyue; Song, Liya

doi:10.1111/jocd.13616

Cited by 39 publications

(29 citation statements)

References 35 publications

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“…Likewise, medium-chain fatty acids protect against inflammation and tumor factors. In addition, short-chain fatty acids can provide anti-inflammatory effects and initiate an immune response [15]. Cui et al [16] suggested the antibacterial and anti-inflammatory properties of fatty acids.…”

Section: Discussionmentioning

confidence: 99%

Characterization of Fatty Acids, Polysaccharides, Amino Acids, and Minerals in Marine Macroalga Chaetomorpha crassa and Evaluation of Their Potentials in Skin Cosmetics

Kalasariya¹,

Patel²,

Yadav

et al. 2021

Molecules

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Cosmetic industries are highly committed to finding natural sources of functional active constituents preferable to safer materials to meet consumers’ demands. Marine macroalgae have diversified bioactive constituents and possess potential benefits in beauty care products. Hence, the present study was carried out to characterize the biochemical profile of marine macroalga Chaetomorpha crassa by using different techniques for revealing its cosmetic potentials. In results, the FTIR study characterized the presence of different bioactive functional groups that are responsible for many skin-beneficial compounds whereas six and fifteen different important phycocompounds were found in GCMS analysis of ethanolic and methanolic extracts, respectively. In the saccharide profile of C. crassa, a total of eight different carbohydrate derivatives were determined by the HRLCMS Q-TOF technique, which showed wide varieties of cosmetic interest. In ICP AES analysis, Si was found to be highest whereas Cu was found to be lowest among other elements. A total of twenty-one amino acids were measured by the HRLCMS-QTOF technique, which revealed the highest amount of the amino acid, Aspartic acid (1207.45 nmol/mL) and tyrosine (106.77 nmol/mL) was found to be the lowest in amount among other amino acids. Their cosmetic potentials have been studied based on previous research studies. The incorporation of seaweed-based bioactive components in cosmetics has been extensively growing due to its skin health-promoting effects.

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Section: Discussionmentioning

confidence: 99%

Characterization of Fatty Acids, Polysaccharides, Amino Acids, and Minerals in Marine Macroalga Chaetomorpha crassa and Evaluation of Their Potentials in Skin Cosmetics

Kalasariya¹,

Patel²,

Yadav

et al. 2021

Molecules

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show abstract

“…28 In our previous study, the decrease of saturated FA content was an important lipid marker for the weakening of skin barrier function, while the increase of unsaturated FA content was an important lipid marker for the destruction of skin barrier function. 29 In addition, although the contents of glycerolphospholipids (GPs) and ceramides (Cers) did not show a trend change, it is worth noting that both GPs and Cers have a positive effect on skin barrier function. 15,30 It seems reasonable, because compared with young men, the contents of GPs and Cers showed obvious effect-dose relationship when skin barrier function was weakened or destroyed.…”

Section: The a Sso Ciati On B E T Ween The Effec T Of S E X Hormone S On S Ebum And S K In Cond Iti Onmentioning

confidence: 98%

Lipidomics demonstrates the association of sex hormones with sebum

Chen

et al. 2021

J of Cosmetic Dermatology

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Sex hormones are divided into androgen and estrogen, which can directly or indirectly regulate the activity of sebaceous glands. Among them, testosterone (T) and dihydrotestosterone (DHT) are most biologically active in androgens. After binding to androgen receptor in the basal layer of sebocytes, the excessive increment and sebum production of sebum cells are promoted by synergistic action with PPAR ligands. 1,2 However, estrogen does not directly affect the activity of sebocytes, but can achieve indirect effects by inhibiting androgen regulation of sebocytes. 3 For example, progesterone can block androgen receptors and inhibit the activity of free androgen in vivo. Estradiol can reduce the level of androgens with bio-active by up-regulating the level of sex hormone-binding globulin. 4 Therefore, sex hormones do have a crucial effect on sebocytes. Importantly, we also supported this by qualitative analysis in the changes of skin surface lipid (SSL) content and composition in people with different sex hormone levels through lipidomics.Lipidomics can conduct a comprehensive and systematic analysis of lipids, reveal the relationship between lipids and cells, organs, and bodies in physiology and pathology by identifying the structure and function of lipids. 5 In the past few years, we used lipidomics (Ultra Performance Liquid Chromatography-Quadrupole Time-of-Flight-Mass Spectrometer, UPLC-QTOF-MS) to analyze the important role of lipids in different skin conditions. [6][7][8][9][10] Including acne vulgaris, sensitive muscles, etc., we found significant differences in SSL in different skin conditions. [10][11][12] Importantly, when we studied the SSL of young men and women and middle-pregnancy women (without obvious skin diseases), we stumbled upon potential consistency in their lipid changes. Through literature research and data analysis, we found that this phenomenon may be related to the level of sex hormones in the body. 13 The regulation of sebocytes by sex hormones leads to the change of sebum. 14 Therefore, this paper focuses on sex hormones and sebum, in order to reveal the important association of sex hormones on sebum.

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“…Many kinds of fatty acids can be used as raw materials, such as lauric acid, myristic acid, palmitic acid, and stearic acid. In addition, FAs are skin components as an important player in the maintenance of normal skin barrier function [99].…”

Section: Fatty Acylsmentioning

confidence: 99%

Lipids from Microalgae for Cosmetic Applications

et al. 2021

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In recent years, there has been considerable interest in using microalgal lipids in the food, chemical, pharmaceutical, and cosmetic industries. Several microalgal species can accumulate appreciable lipid quantities and therefore are characterized as oleaginous. In cosmetic formulations, lipids and their derivatives are one of the main ingredients. Different lipid classes are great moisturizing, emollient, and softening agents, work as surfactants and emulsifiers, give consistence to products, are color and fragrance carriers, act as preservatives to maintain products integrity, and can be part of the molecules delivery system. In the past, chemicals have been widely used but today’s market and customers’ demands are oriented towards natural products. Microalgae are an extraordinary source of lipids and other many bioactive molecules. Scientists’ attention to microalgae cultivation for their industrial application is increasing. For the high costs associated, commercialization of microalgae and their products is still not very widespread. The possibility to use biomass for various industrial purposes could make microalgae more economically competitive.

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A review of fatty acids influencing skin condition

Cited by 39 publications

References 35 publications

Characterization of Fatty Acids, Polysaccharides, Amino Acids, and Minerals in Marine Macroalga Chaetomorpha crassa and Evaluation of Their Potentials in Skin Cosmetics

Characterization of Fatty Acids, Polysaccharides, Amino Acids, and Minerals in Marine Macroalga Chaetomorpha crassa and Evaluation of Their Potentials in Skin Cosmetics

Lipidomics demonstrates the association of sex hormones with sebum

Lipids from Microalgae for Cosmetic Applications

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