Lipids from Microalgae for Cosmetic Applications

Luca, Maria De; Pappalardo, Ilaria; Limongi, Antonina Rita; Viviano, Emanuele; Radice, Rosa Paola; Todisco, Simona; Martelli, Giuseppe; Infantino, Vittoria; Vassallo, Antonio

doi:10.3390/cosmetics8020052

Cited by 62 publications

(29 citation statements)

References 149 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Euglena gracilis is a microalga that produces a large quantity of wax-ester as a byproduct of the biodegradation of storage polysaccharides. These wax-esters are now used in biofuel generation but could possibly be useful in cosmetics [154]. Waxes, for example, are important components in lipsticks because they give the stick sufficient rigidity, hardness, stability, and texture.…”

Section: Role Of Fatty Acids In Cosmeceuticalsmentioning

confidence: 99%

Phytochemical and Potential Properties of Seaweeds and Their Recent Applications: A Review

et al. 2022

View full text Add to dashboard Cite

Since ancient times, seaweeds have been employed as source of highly bioactive secondary metabolites that could act as key medicinal components. Furthermore, research into the biological activity of certain seaweed compounds has progressed significantly, with an emphasis on their composition and application for human and animal nutrition. Seaweeds have many uses: they are consumed as fodder, and have been used in medicines, cosmetics, energy, fertilizers, and industrial agar and alginate biosynthesis. The beneficial effects of seaweed are mostly due to the presence of minerals, vitamins, phenols, polysaccharides, and sterols, as well as several other bioactive compounds. These compounds seem to have antioxidant, anti-inflammatory, anti-cancer, antimicrobial, and anti-diabetic activities. Recent advances and limitations for seaweed bioactive as a nutraceutical in terms of bioavailability are explored in order to better comprehend their therapeutic development. To further understand the mechanism of action of seaweed chemicals, more research is needed as is an investigation into their potential usage in pharmaceutical companies and other applications, with the ultimate objective of developing sustainable and healthier products. The objective of this review is to collect information about the role of seaweeds on nutritional, pharmacological, industrial, and biochemical applications, as well as their impact on human health.

show abstract

Section: Role Of Fatty Acids In Cosmeceuticalsmentioning

confidence: 99%

Phytochemical and Potential Properties of Seaweeds and Their Recent Applications: A Review

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Moreover, the demand for algal neutral lipids is recently increasing in cosmeceutical and food industries as a replacement of extracted plants due to their high productivity. These are usually used in cosmetic products as fragrance carriers, neutral bases, and bioactive ingredients for their moisturizing and softening properties, and for providing texture [ 36 ]. Chlamydomonas was certified as ‘Generally Recognized As Safe’ (GRAS), and its pharmaceutical industrial application is increasing in the global market.…”

Section: Resultsmentioning

confidence: 99%

Inhibition of monogalactosyldiacylglycerol synthesis by down-regulation of MGD1 leads to membrane lipid remodeling and enhanced triacylglycerol biosynthesis in Chlamydomonas reinhardtii

Lee

Jin

et al. 2022

Biotechnol Biofuels

View full text Add to dashboard Cite

Background Membrane lipid remodeling involves regulating the physiochemical modification of cellular membranes against abiotic stress or senescence, and it could be a trigger to increase neutral lipid content. In algae and higher plants, monogalactosyldiacylglycerol (MGDG) constitutes the highest proportion of total membrane lipids and is highly reduced as part of the membrane lipid remodeling response under several abiotic stresses. However, genetic regulation of MGDG synthesis and its influence on lipid synthesis has not been studied in microalgae. For development of an industrial microalgae strain showing high accumulation of triacylglycerol (TAG) by promoting membrane lipid remodeling, MGDG synthase 1 (MGD1) down-regulated mutant of Chlamydomonas reinhardtii (Cr-mgd1) was generated and evaluated for its suitability for biodiesel feedstock. Results The Cr-mgd1 showed a 65% decrease in CrMGD1 gene expression level, 22% reduction in MGDG content, and 1.39 and 5.40 times increase in diacylglyceryltrimethylhomoserines (DGTS) and TAG, respectively. The expression levels of most genes related to the decomposition of MGDG (plastid galactoglycerolipid degradation1) and TAG metabolism (diacylglycerol O-acyltransferase1, phospholipid:diacylglycerol acyltransferase, and major lipid droplet protein) were increased. The imbalance of DGDG/MGDG ratio in Cr-mgd1 caused reduced photosynthetic electron transport, resulting in less light energy utilization and increased reactive oxygen species levels. In addition, endoplasmic reticulum stress was induced by increased DGTS levels. Thus, accelerated TAG accumulation in Cr-mgd1 was stimulated by increased cellular stress as well as lipid remodeling. Under high light (HL) intensity (400 µmol photons/m2/s), TAG productivity in Cr-mgd1–HL (1.99 mg/L/d) was 2.71 times higher than that in wild type (WT–HL). Moreover, under both nitrogen starvation and high light intensity, the lipid (124.55 mg/L/d), TAG (20.03 mg/L/d), and maximum neutral lipid (56.13 mg/L/d) productivity were the highest. Conclusions By inducing lipid remodeling through the mgd1 gene expression regulation, the mutant not only showed high neutral lipid content but also reached the maximum neutral lipid productivity through cultivation under high light and nitrogen starvation conditions, thereby possessing improved biomass properties that are the most suitable for high quality biodiesel production. Thus, this mutant may help understand the role of MGD1 in lipid synthesis in Chlamydomonas and may be used to produce high amounts of TAG.

show abstract

“…Certainly, aging is a natural and inevitable process, but the incorporation of emollient components in topical formulations can be effective in preventing dehydration and in maintaining skin health. Vegetable oils have emollient properties and are therefore frequently used in dermatological and cosmetic formulations [12].…”

Section: Lipid Barriers Of the Epidermismentioning

confidence: 99%

Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair

et al. 2021

View full text Add to dashboard Cite

The use of lipids in the composition of polymeric-based films for topical administration of bioactive ingredients is a recent research topic; while few products are commercially available, films containing lipids represent a strategic area for the development of new products. Some lipids are usually used in polymeric-based film formulations due to their plasticizing action, with a view to improving the mechanical properties of these films. On the other hand, many lipids have healing, antimicrobial, anti-inflammatory, anti-aging properties, among others, that make them even more interesting for application in the medical-pharmaceutical field. This manuscript discusses the production methods of these films both on a laboratory and at industrial scales, the properties of the developed biopolymers, and their advantages for the development of dermatologic and cosmetic products.

show abstract

Lipids from Microalgae for Cosmetic Applications

Cited by 62 publications

References 149 publications

Phytochemical and Potential Properties of Seaweeds and Their Recent Applications: A Review

Phytochemical and Potential Properties of Seaweeds and Their Recent Applications: A Review

Inhibition of monogalactosyldiacylglycerol synthesis by down-regulation of MGD1 leads to membrane lipid remodeling and enhanced triacylglycerol biosynthesis in Chlamydomonas reinhardtii

Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair

Contact Info

Product

Resources

About