A Review of Bark-Extract-Mediated Green Synthesis of Metallic Nanoparticles and Their Applications

Abstract

Nanoparticles are intensely studied because of their importance in diverse fields of biotechnology, especially in medicine. This paper highlights that waste bark can be a cheap source of biocompounds, with high recovery and functionalization potential in nanoparticle synthesis. Due to their biocompatibility and activity as antioxidant, antimicrobial, and anticancer agents, the green synthesis of metallic nanoparticles is of great importance. This review aims to bring together the diversity of synthesized metallic nanoparticles mediated by bark extracts obtained from different woody vascular plants, the phytoconstituents responsible for the reduction of metal salts, and the activity of metallic nanoparticles as diverse agents in combating the microbial, oxidant, and cancer activity. The literature data highlight the fact that metallic nanoparticles obtained from natural compounds are proven reducing agents with multiple activities. Thus, the activity of natural components in environmental protection and human health is confirmed.

Synthesis, optimization and characterization of silver nanoparticles using the catkin extract of Piper longum for bactericidal effect against food-borne pathogens via conventional and mathematical approaches

“…These results indicate that the polyphenols and proteins in the catkin extract have acted as reducing, capping and stabilizing agents, for the nanoparticles, as predicted by the FTIR peaks. They might also have acted as agents for elevated antimicrobial activity as compared to the nanoparticles synthesized by chemical means [48] , [49] , [50] , [51] , [52] , [53] .

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Efficacy of Antimicrobial and Larvicidal Activities of Green Synthesized Silver Nanoparticles Using Leaf Extract of Plumbago auriculata Lam

“…Currently, several studies have been reported to produce plant-based eco-friendly repellents possessing larvicidal activity [ 21 , 22 ]. These medicinal plants are used for the synthesis of silver, gold, platinum, copper, and titanium nanoparticles having potent antimicrobial, antioxidant, and anticancer properties [ 23 , 24 ]. These medicinal plants naturally possess bio-surfactant molecules, also called secondary metabolites, such as flavonoids, alkaloids, tannins, saponins, glycosides, and phenols.…”

Biogenic synthesis of silver nanoparticles using Paenibacillus sp. in-vitro and their antibacterial, anticancer activity assessment against human colon tumour cell line

“…Nanomedicine is a promising area that can induce changes affecting cancer treatment protocols, and the green synthesized AgNPs are effective anticancer mediators used for detection, prevention and bioremediation of tumour cells. AgNPs are intimately investigated for their promising anticancer property exhibited against different human cancer cell lines, like IMR-90, MCF-7, U251, MDA-MB-231, HT-29, HeLa, A-549 and HepG2 tumour cells (Burdusel et al, 2018;Burlacu et al, 2019;Nayaka et al, 2020;Rajoka et al, 2020).…”