A retrospective study of clozapine and urinary incontinence in Chinese in‐patients

Lin, Chao-Cheng; Bai, Ya Mei; Chen, J. Y.; Lan, Tsuo Hung

doi:10.1111/j.1600-0447.1999.tb10837.x

Cited by 37 publications

(60 citation statements)

References 6 publications

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“…There are also a number of relatively large studies that showed sexual dysfunction to be more frequent in people with schizophrenia compared to normal controls (133)(134)(135). Increased prevalence of incontinence in people with schizophrenia have also been reported (136,137). Population-based studies on prostate cancer consistently found reduced incidences in people with schizophrenia (57,58,(61)(62)(63)(64)68), please note again that the samples in the Danish studies partly overlapped (61,68).…”

Section: Diseases Of the Nervous System (15 170 Medline Hits)mentioning

confidence: 98%

Physical illness and schizophrenia: a review of the literature

Leucht

Burkard

Henderson³

et al. 2007

Acta Psychiatr Scand

560

358

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Sartorius N. Physical illness and schizophrenia: a review of the literature.Objective: The lifespan of people with schizophrenia is shortened compared to the general population. We reviewed the literature on comorbid physical diseases in schizophrenia to provide a basis for initiatives to fight this unacceptable situation. Method: We searched MEDLINE (1966( -May 2006 combining the MeSH term of schizophrenia with the 23 MeSH terms of general physical disease categories to identify relevant epidemiological studies. Results: A total of 44 202 abstracts were screened. People with schizophrenia have higher prevalences of HIV infection and hepatitis, osteoporosis, altered pain sensitivity, sexual dysfunction, obstetric complications, cardiovascular diseases, overweight, diabetes, dental problems, and polydipsia than the general population. Rheumatoid arthritis and cancer may occur less frequently than in the general population. Eighty-six per cent of the studies came from industrialized countries limiting the generalizability of the findings. Conclusion: The increased frequency of physical diseases in schizophrenia might be on account of factors related to schizophrenia and its treatment, but undoubtedly also results from the unsatisfactory organization of health services, from the attitudes of medical doctors, and the social stigma ascribed to the schizophrenic patients. Summations• According to this review it has been known for decades that incidences physical diseases are frequent in schizophrenia. Nevertheless, some areas such as infectious diseases have not been sufficiently studied.• Psychiatrists are often not trained well enough in the detection and treatment of physical diseases.They must be aware of the frequent medical comorbidities and should play a more active role in their diagnosis, prevention, and treatment.• Other necessary strategies include the education of patients, general practitioners and of doctors working in other medical specialities. The access to medical care of the mentally ill also needs to be improved, among others, by reducing the stigma associated with mental disorders. Considerations• The review covered a broad area of research accordingly, focusing attention to details has not been possible.• Despite the broad search strategy, studies not covered by MEDLINE or not indexed by the MeSH term of schizophrenia could have been missed. • Due to considerable differences in the design and quality of the studies in assorted and diverse areas, quantitative approaches using meta-analysis were not possible, but should be the target of future reviews focusing.

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Section: Diseases Of the Nervous System (15 170 Medline Hits)mentioning

confidence: 98%

Physical illness and schizophrenia: a review of the literature

Leucht

Burkard

Henderson³

et al. 2007

Acta Psychiatr Scand

560

358

View full text Add to dashboard Cite

show abstract

“…Clozapine-induced sialorrhoea occurs at a rate of approximately 30%, although it varies from 10 to 80% in the literature [1]. Nocturnal enuresis is a less frequently reported side-effect and incidence varies from 0.23% [2] to 41% [3]. It is possible that the occurrence of sialorrhoea and enuresis contributes to poor medication compliance.…”

mentioning

confidence: 94%

Amitriptyline for clozapine‐induced nocturnal enuresis and sialorrhoea

Praharaj

Arora

2006

Brit J Clinical Pharma

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“…[2] Nocturnal enuresis is a less commonly reported side effect with a reported frequency varying from as little as 0.23% to as high as 41%. [3,4] We wish to report here a case of schizophrenia along with harmful use of cannabis, who developed both sialorrhea and enuresis while on clozapine, and who showed improvement in both the symptoms after receiving trihexiphenidyl.…”

Section: Trihexyphenidyl (Benzhexol) In Clozapine-induced Nocturnal Ementioning

confidence: 99%

Trihexyphenidyl (benzhexol) in clozapine-induced nocturnal enuresis and sialorrhea

Aggarwal¹,

Garg²,

Jiloha³

2009

Indian J Med Sci

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A retrospective study of clozapine and urinary incontinence in Chinese in‐patients

Abstract: Clozapine-associated urinary incontinence may be persistent in some patients, and it should be cautiously monitored in every patient taking clozapine.

Cited by 37 publications

References 6 publications

Physical illness and schizophrenia: a review of the literature

Physical illness and schizophrenia: a review of the literature

Amitriptyline for clozapine‐induced nocturnal enuresis and sialorrhoea

Trihexyphenidyl (benzhexol) in clozapine-induced nocturnal enuresis and sialorrhea

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