A retrospective study: ABO and Rh phenotype blood group distribution among blood donors in H.N.B. Base Hospital, Srinagar, Uttarakhand, India

Abstract

Objective:To determine the prevalence of ABO and Rh blood groups based on the antigenic presence on the surface of red blood cells with respect to gender and calculate allele frequency of the blood groups. Globally, approximately 700 type red cell antigens have been identified till now. ABO and Rh blood groups play an important role in the process of blood transfusion, resolving certain medicolegal issues, parental testing, and various genetic studies.Methods:This study was conducted in H.N.B. Base Hospital, Srinagar, Uttarakhand, from January 2012 to December 2016. Relevant data of blood donors were collected from blood bank department of the hospital. Blood grouping was conducted using commercially available standard monoclonal antisera applying test tube and column agglutination techniques.Results:Out of 9883 individuals, 9333 (92.4%) were males and 750 (7.6%) were female individuals. The most common blood group found was B (31.68%) and least common being AB (11.70%). The prevalence of Rhesus positive and negative distribution in the present studied population was found as 93.51% and 6.49%, respectively. Overall, male ABO group pattern found was shown by formula B > A > O > AB which was similar among Rh-positive male individuals while Rh-negative males' pattern was found as A > B = O > AB. In females, ABO group pattern was B > O > A > AB which was similar to Rh-positive female pattern while differs in Rh negative. The estimated allele frequencies were found as 0.2403, 0.2475, and 0.5122 for IA (p), IB (q), and IO (r), respectively.Conclusion:The most common blood group found among the Gharwali donors was B positive while the least common was AB negative, which plays an important contribution for making government policies to develop National Health Program.

Phenotypic and Allelic Frequency of ABO and Rh (D) Blood Group among Whole Blood Donors in a Teaching Hospital of Chhattisgarh

“…We compared ABO & Rh (D) distribution across different states of India [3,[10][11][12][13][14][15][16][17][18][19][20] ( The distribution of ABO blood group varies across neighbouring [21][22][23] & other countries [24][25][26][27][28] of the world as seen in Table 5. In India O & B phenotypes are common; whereas in America [27] & Europe [28] O & A phenotypes are common.…”

Hematological malignancies in relation with ABO blood group at a teaching hospital, Varanasi, India

“…The blood group can be used as an epidemiological marker for selecting population subgroups that may be at risk of developing different hematological malignancies. [ 17 18 ]…”

Frequency and Distribution of ABO and Rhesus (D) Blood group Antigens among Blood Donors at a District Hospital Blood Bank in North Goa

“…2 ABO and Rh blood grouping is important primarily during transfusion of blood and its components, during organ transplantation, for medico legal research, for population genetic studies, to study the association of blood groups with various diseases and for research purposes. [1][2][3][4][5] The prevalence of different blood groups varies between different regions and races. It is important to have a good knowledge ABOut the distribution of ABO and Rh blood groups in the community, for appropriate planning of the regional blood bank activities, to manage blood bank inventory and to aid in providing safe and appropriate blood to patients, to prevent transfusion reactions in the blood recipients.…”