A redox reaction-induced ratiometric fluorescence platform for the specific detection of ascorbic acid based on Ag<sub>2</sub>S quantum dots and multifunctional CoOOH nanoflakes

Chen, Haoyu; Cai, Zifu; Gui, Jialing; Tang, Ying; Yin, Peng; Zhu, Xiaohua; Li, Haitao; Zhang, Youyu; Liu, Meiling; Yao, Shouzhuo

doi:10.1039/d2tb02438a

Cited by 20 publications

(11 citation statements)

References 48 publications

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“…Additionally, the peak at 584 cm −1 is attributed to the Co–O 2− complex vibration, affirming the successful synthesis of CoOOH NPs. 47…”

Section: Resultsmentioning

confidence: 99%

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Protein-coated cobalt oxide–hydroxide nanospheres deliver photosensitizer IR780 iodide for near-infrared light-triggered photodynamic/photothermal/chemodynamic therapy against colon cancer

Hu,

Yao,

et al. 2023

J. Mater. Chem. B

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“…Additionally, the peak at 584 cm −1 is attributed to the Co–O 2− complex vibration, affirming the successful synthesis of CoOOH NPs. 47…”

Section: Resultsmentioning

confidence: 99%

“…Additionally, the peak at 584 cm À1 is attributed to the Co-O 2À complex vibration, affirming the successful synthesis of CoOOH NPs. 47 Subsequently, a series of characterization tests were conducted to validate both the effective IR780 loading and BSA coating on CoIRB NPs. As shown in Fig.…”

Section: Construction and Characterizationmentioning

confidence: 99%

Protein-coated cobalt oxide–hydroxide nanospheres deliver photosensitizer IR780 iodide for near-infrared light-triggered photodynamic/photothermal/chemodynamic therapy against colon cancer

Hu,

Yao,

et al. 2023

J. Mater. Chem. B

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“…The Michaelis−Menten constants (Km) and maximum initial velocity (Vmax) of MnO 2 NFs toward OPD were calculated to be 1.19 mM and 1.76 × 10 −4 mM s −1 , respectively. Since oxOPD is also a yellow emissive fluorescent substance, 44 an obvious fluorescence emission peak at 570 nm can be observed in the fluorescence spectra of the mixture solution of MnO 2 NFs and OPD (Figure 3A). Moreover, MnO 2 NFs can be reduced into colorless Mn 2+ by AA, thus losing its oxidase-mimicking activity.…”

Section: Feasibility Of the Mno 2 Nf-based Ratiometric Fluorescencementioning

confidence: 99%

Ratiometric Fluorescence Immunoassay Based on MnO₂ Nanoflakes for Sensitive and Accurate Detection of Tricaine

Liang

Jia

Zhang

et al. 2023

J. Agric. Food Chem.

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Tricaine is a common anesthetic used in the long-distance transport of live fish. Recently, its negative impact on human health has aroused extensive concern. Thus, rapid and reliable techniques for tricaine residue analysis are essential to ensuring the quality of aquatic products. Herein, a specific anti-tricaine monoclonal antibody (Mab) was prepared. Then, a sensitive and robust ratiometric fluorescence ELISA (RF-ELISA) was constructed for detecting tricaine based on two MnO 2 nanoflakemediated (MnO 2 NFs) fluorogenic reactions. In the RF-ELISA protocol, MnO 2 NFs with oxidase-like activity can trigger the formation of fluorescent 2,3-diaminophenazine (oxOPD) with an emissive peak at 570 nm from non-fluorescent ophenylenediamine (OPD), while ascorbic acid (AA) can decompose MnO 2 NFs to lose their oxidase-mimicking activity, which is accompanied by the oxidation of AA into dehydroascorbic acid (DHAA). The subsequent reaction between the generated DHAA and OPD will result in the production of 3-(1,2-dihydroxy ethyl)furo [3,4-b]quinoxalin-1(3H)-on (DFQ), which has a potent emission peak at 445 nm. By virtue of the alkaline phosphatase (ALP) labeled on the antibody, which can catalyze the production of AA from ascorbic acid 2-phosphate (AAP), the concentration of tricaine can be linked to the variation of the RF signal (F 445 /F 570 ) via a competitive immunoreaction. After optimization, RF-ELISA displayed a detection limit (LOD) of 0.28 ng/mL toward tricaine (in buffer solution), which was 376-fold lower than that of the traditional colorimetric ELISA. For practical application, the LODs of RF-ELISA for tricaine detection in shrimp and tilapia samples were determined to be 2.8 and 5.6 ng/g, respectively. Recoveries for spiked shrimp and tilapia samples, as well as the validation data from LC−MS/MS, showed that RF-ELISA exhibited good accuracy, precision, and reliability. This RF-ELISA protocol opened up new ways for tricaine and other-target analyses in food safety detection.

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“…However, this approach relies heavily on the quality of colorimetric detection. [193] Copyright 2023, Royal Society of Chemistry. B) Schematic diagram of immunosensor preparation process for ENR detection.…”

Section: Ascorbic Acidmentioning

confidence: 99%

“…A) Schematic illustration of the synthesis of Ag 2 S QDs and construction of the AA sensing platform based on Ag 2 S QDs-CoOOH NFs-OPD. Reproduced with permission [193]. Copyright 2023, Royal Society of Chemistry.…”

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confidence: 99%

Co‐based Nanozymatic Profiling: Advances Spanning Chemistry, Biomedical, and Environmental Sciences

Li,

Cai,

Jiang

et al. 2023

Advanced Materials

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Nanozymes, next‐generation enzyme‐mimicking nanomaterials, have entered an era of rational design; among them, Co‐based nanozymes have emerged as captivating players over times. Co‐based nanozymes were developed and have garnered significant attention over the past five years. Their extraordinary properties, including regulatable enzymatic activity, stability, and multifunctionality stemming from magnetic properties, photothermal conversion effects, cavitation effects, and relaxation efficiency, have made Co‐based nanozymes a rising star. This review presents the first comprehensive profiling of the Co‐based nanozymes in the chemistry, biology, and environmental sciences. The review begins by scrutinizing the various synthetic methods employed for Co‐based nanozyme fabrication, such as template and sol‐gel methods, highlighting their distinctive merits from a chemical standpoint. Furthermore, we provide a detailed exploration of their wide‐ranging applications in biosensing and biomedical therapeutics, as well as their contributions to environmental monitoring and remediation. Notably, drawing inspiration from state‐of‐the‐art techniques such as omics, a comprehensive analysis of Co‐based nanozymes is undertaken, employing analogous statistical methodologies to provide valuable guidance. To conclude, we present a comprehensive outlook on the challenges and prospects for Co‐based nanozymes, spanning from microscopic physicochemical mechanisms to macroscopic clinical translational applications.This article is protected by copyright. All rights reserved

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A redox reaction-induced ratiometric fluorescence platform for the specific detection of ascorbic acid based on Ag₂S quantum dots and multifunctional CoOOH nanoflakes

Abstract: In this work, a ratiometric fluorescent nanoplatform for the detection of AA was constructed based on the Ag2S quantum dots (QDs) and multifunctional hydroxyl cobalt oxide nanoflakes (CoOOH NFs). Ag2S...

Cited by 20 publications

References 48 publications

Protein-coated cobalt oxide–hydroxide nanospheres deliver photosensitizer IR780 iodide for near-infrared light-triggered photodynamic/photothermal/chemodynamic therapy against colon cancer

Protein-coated cobalt oxide–hydroxide nanospheres deliver photosensitizer IR780 iodide for near-infrared light-triggered photodynamic/photothermal/chemodynamic therapy against colon cancer

Ratiometric Fluorescence Immunoassay Based on MnO₂ Nanoflakes for Sensitive and Accurate Detection of Tricaine

Co‐based Nanozymatic Profiling: Advances Spanning Chemistry, Biomedical, and Environmental Sciences

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A redox reaction-induced ratiometric fluorescence platform for the specific detection of ascorbic acid based on Ag2S quantum dots and multifunctional CoOOH nanoflakes

Abstract: In this work, a ratiometric fluorescent nanoplatform for the detection of AA was constructed based on the Ag2S quantum dots (QDs) and multifunctional hydroxyl cobalt oxide nanoflakes (CoOOH NFs). Ag2S...

Cited by 20 publications

References 48 publications

Protein-coated cobalt oxide–hydroxide nanospheres deliver photosensitizer IR780 iodide for near-infrared light-triggered photodynamic/photothermal/chemodynamic therapy against colon cancer

Protein-coated cobalt oxide–hydroxide nanospheres deliver photosensitizer IR780 iodide for near-infrared light-triggered photodynamic/photothermal/chemodynamic therapy against colon cancer

Ratiometric Fluorescence Immunoassay Based on MnO2 Nanoflakes for Sensitive and Accurate Detection of Tricaine

Co‐based Nanozymatic Profiling: Advances Spanning Chemistry, Biomedical, and Environmental Sciences

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A redox reaction-induced ratiometric fluorescence platform for the specific detection of ascorbic acid based on Ag₂S quantum dots and multifunctional CoOOH nanoflakes

Ratiometric Fluorescence Immunoassay Based on MnO₂ Nanoflakes for Sensitive and Accurate Detection of Tricaine