A ratiometric fluorescent chemosensor for Hg2+ based on FRET and its application in living cells

Wang, Cuicui; Zhang, Di; Huang, Xiaoyan; Ding, Peigang; Wang, Zhenji; Zhao, Yufen; Ye, Yong

doi:10.1016/j.snb.2014.03.032

Cited by 83 publications

(27 citation statements)

References 39 publications

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“…2,33,[42][43][44][45][46][47][48][49][50][51] Most importantly, Hg 2+ can easily promote desulfurization to transform a cyclic compound, as an imidazole (1-R-2-R′-4,5-dihydro-1H-imidazole), resulting in a change of the spectroscopy properties. 2,42,44,50,51 Also, this phenomenon can be ascribed to changes of the electronic delocalization in the chromophore. 49 Thiourea moiety in VBF, as an electrondonating group, has little influence on the spectroscopy properties from FITC because of the ethylene spacer.…”

Section: Sensitive and Selective Recognition Of Hgmentioning

confidence: 99%

Fabrication of Water-soluble Fluorescent Polymeric Micelles for Selective Detection of Hg2+ in Blood Serum

et al. 2017

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In this study, amphiphilic diblock copolymers were designed and synthesized via the incorporation of reversible additionfragmentation chain transfer radical polymerization (RAFT) and a subsequent grafting technique. Subsequently, Hg 2+ -sensitive water-soluble fluorescent polymeric micelles (FNs) were prepared by a reprecipitation strategy. The spectroscopic characteristics demonstrate that the fluorescein isothiocyanate (FITC) was successfully linked into the polymer. Due to the promoted reaction of desulfurization cyclization by Hg 2+ , the fluorescence of fluorescein in FNs was obviously quenched. The as-prepared FNs showed admirable Hg 2+ -sensitivity (detection limit: 54 nM), excellent water-solubility and high selectivity. In addition, FNs were successfully used to determine Hg 2+ in blood serum. We expected that the as-prepared FNs could perform potential applications in imaging, sensing, and bioanalytic chemistry.

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Section: Sensitive and Selective Recognition Of Hgmentioning

confidence: 99%

Fabrication of Water-soluble Fluorescent Polymeric Micelles for Selective Detection of Hg2+ in Blood Serum

et al. 2017

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“…Bioimaging applications of compound L in EC 109 cells [39,40] To further assess the potential applications of the probe in living cells, the double-channel fluorescent imaging inside EC 109 cells was monitored by fluorescence microscopy (S- Fig. 11).…”

Section: Mechanismmentioning

confidence: 99%

A new FRET ratiometric fluorescent chemosensor for Hg2+ and its application in living EC 109 cells

Song

Huai

Wang

et al. 2015

Spectrochimica Acta Part A: Molecular and Biomolecular Spectros

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“…[3][4][5][6][7][8][9][10][11] In recent years, considerable efforts have been made to take advantage of rhodamine dyes in constructing fluorometric probes for metal ions, [12][13][14][15][16] and a number of excellent fluorescent probes for Cu 2+ or Hg 2+ have been reported. [17][18] However, the probes that can sense two or more mental ions separately were rarely reported.…”

Section: Introductionmentioning

confidence: 99%

A Dansyl-Rhodamine Based Fluorescent Probe for Detection of Hg2+ and Cu2+

Yuan¹,

Su²,

Wang³

2017

ACSi

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A novel fluorescent probe based on dansyl-appended rhodamine B was developed. The probe can selectively recognize and sense Hg 2+ and Cu 2+ from other common metal ions by showing unique fluorescence and absorption characteristics. In MeCN/HEPES buffer solution, the probe gives a ratiometric fluorescent response to Hg 2+ , which was ascribed to the fluorescence resonance energy transfer from dansyl moiety to the ring-opened rhodamine B moiety, while the presence of Cu 2+ causes fluorescence quenching. Beside the fluorescence change, the presence of Cu 2+ and Hg 2+ can induce intensive absorption at about 555 nm, which resulted in a color change from colorless to pink.

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A ratiometric fluorescent chemosensor for Hg2+ based on FRET and its application in living cells

Cited by 83 publications

References 39 publications

Fabrication of Water-soluble Fluorescent Polymeric Micelles for Selective Detection of Hg2+ in Blood Serum

Fabrication of Water-soluble Fluorescent Polymeric Micelles for Selective Detection of Hg2+ in Blood Serum

A new FRET ratiometric fluorescent chemosensor for Hg2+ and its application in living EC 109 cells

A Dansyl-Rhodamine Based Fluorescent Probe for Detection of Hg2+ and Cu2+

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