A Rare Presentation of Giant Pilomatricoma Located on the Back

Göktay, Fatıh; Mansur, Ayşe Tülin; Aydıngöz, İkbal Esen; Serdar, Zehra Aşiran; Öncel, Çağda ÇELi̇KTEN; Aker, Fügen

doi:10.1111/j.1524-4725.2007.33118.x

Cited by 8 publications

(10 citation statements)

References 28 publications

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“…16 However, if one component predominates, this may lead to an erroneous diagnosis of other benign and malignant lesions and the final diagnosis is made by histopathologic analysis. 5 The histopathology of PM shows a well-circumscribed, deep dermal or dermal-subcutaneous tumor formed by basaloid cells that gradually lose their nuclei and mingle with the eosinophilic shadow cells that show the ghosts of epithelial cells without viable colors. The basophilic cells typically observed in this type of lesion were not evident in this case, which indicates an old lesion.…”

Section: Discussionmentioning

confidence: 99%

“…Since 1974, when Krausen et al 9 described the first case of giant PM (GPM), few similar lesions were described 5 and most of them were reported in male patients during the second and sixth decades of life, mainly located on the head, neck, and upper extremities, being very rare on the back. 5 Zamanian et al 10 reported 45 cases of PM and the tumors ranged in size from 0.5 to 3.5 cm; in only five cases the tumors were larger than 2.0 cm. In the literature there are few reports of GPM in the dorsal trunk location in female patients.…”

Section: Case Reportmentioning

confidence: 99%

“…If there is recurrence, a wider excision and a more detailed histopathologic analysis are required. 5 The spontaneous…”

Section: Cells With Shadows Of Lost Nuclei and Clear Intercellular LImentioning

confidence: 99%

“…6 It is a common skin neoplasm in the pediatric population, but it may be found in all age groups with bimodal peaks under the age of 30 and in the sixth/seventh decades of life. 5,6 Uncommon clinical-pathological variants of PM have been reported, such as bullous like, anetodermic, exophytic, perforating/ulcerated and lymphagiectatic. Multiple and familial cases have been described in association with myotonic dystrophy, Turner's syndrome, Gardner's syndrome, xeroderma pigmentosum, basal cell nevus syndrome and Sotos syndrome.…”

Section: Introductionmentioning

confidence: 99%

“…Pain and tenderness may be associated symptoms. 3,5 The tumor is generally observed on the head, neck and upper extremities. 6 It is a common skin neoplasm in the pediatric population, but it may be found in all age groups with bimodal peaks under the age of 30 and in the sixth/seventh decades of life.…”

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An unusual presentation of giant pilomatrixoma in an adult patient

Souto

Matsushita²,

Matsushita³

et al. 2013

J Dermatol Case Rep

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Background: Pilomatrixoma (OMIM ID #132600) is a benign cutaneous tumor originating from the pilosebaceous follicle and characterized by the presence of subcutaneous nodules of up to 3.0 cm in diameter, usually on the head, neck and upper extremities. It is most common in the first two decades of life and after the age of 60.Main observations: An adult female patient was evaluated, presenting a solid tumoral lesion with erythematous surface and purplish tone, with approximately 7.5 x 5.0 cm in size, in the interscapulovertebral region. It was thought to be an epidermoid cyst, sarcoma, calcified hemangioma, giant dermatofibroma, or nodular basal cell carcinoma. The resection of the lesion was carried out and, at the histological examination, specific details were observed that led to the diagnosis of pilomatrixoma. Conclusion:Pilomatrixoma should be suspected in the differential diagnosis of giant adnexal tumors. (J Dermatol Case Rep. 2013; 7(2): 56-59) An unusual presentation of giant pilomatrixoma in an adult patient IntroductionPilomatrixoma (PM; OMIM ID #132600) was first described in 1880 by Malherbe and Chenatais as a "calcified epithelioma of Malherbe" originated from sebaceous glands. In 1961, Forbis and Helwig demonstrated that the tumor originated from the hair matrix; therefore, the name pilomatrixoma. 1-3 PM is the most common hair-follicle tumor and it accounts for one of every 500 specimens submitted by dermatologists. 4 Clinically, the lesion is a benign cutaneous tumor usually characterized by a solitary asymptomatic, firm, and skin-colored faint blue/red nodule in the deep dermis and subcutaneous tissue, with an average size of 0.5 to 3.0 cm. The lesions larger than 5.0 cm are defined as giant pilomatrixomas. Pain and tenderness may be associated symptoms. 3,5 The tumor is generally observed on the head, neck and upper extremities. 6 It is a common skin neoplasm in the pediatric population, but it may be found in all age groups with bimodal peaks under the age of 30 and in the sixth/seventh decades of life. 5,6 Uncommon clinical-pathological variants of PM have been reported, such as bullous like, anetodermic, exophytic, perforating/ulcerated and lymphagiectatic. Multiple and familial cases have been described in association with myotonic dystrophy, Turner's syndrome, Gardner's syndrome, xeroderma pigmentosum, basal cell nevus syndrome and Sotos syndrome. 6,7 The present paper reports an unusual and uncommon case of pilomatrixoma on the back of an adult female patient. Case ReportA 54-year-old female patient sought the medical specialties outpatient service at School of Medical Sciences at Universidade de Marília (UNIMAR) complaining about a back injury three years ago, with progressive growth and sporadic local pain. The patient had undergone a surgery for the removal of the lesion in another hospital two and a half years before, but there was local recurrence 3 months after surgery. Krausen et al. 9 described the first case of giant PM (GPM), few similar lesions were described 5 a...

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Section: Discussionmentioning

confidence: 99%