A Rare Presentation of Dual Ovarian Pathologies: Small Cell Carcinoma of the Ovary and Mucinous Ovarian Cancer

Abstract

The small cell carcinoma of ovaries co-occurring with mucinous ovarian cancer is a rare event. We report a 21-years-old lady with a composite tumour comprising small cell carcinoma and mucinous carcinoma of ovaries. The incidental finding of the left ovarian cyst led to further workup and revealed a solid cystic mass in the left adnexal area pathologically proven to be mucinous ovarian carcinoma. The initial surgery was deferred upon the patient's request. After a few more cycles of chemotherapy, at the completion of surgery as per ovarian protocol, the pathological evaluation showed small cell carcinoma in the left ovary with a residual focus of mucinous carcinoma. In contrast, the right ovary also showed surface deposits of small cell carcinoma. The patient's clinical condition deteriorated very rapidly after that, and she passed away. Early recognition of small cell carcinoma in a composite tumour is critically essential for timely intervention.

Case report: Strategies for improving outcomes in patients with primary ovarian small-cell neuroendocrine carcinoma

“…months of follow-up. In 2021, Syed A. Mannan et al(10) performed tumor reduction plus 1 cycle of cisplatin + etoposide chemotherapy in one stage IC patient, who died after 10 months of follow-up. These data demonstrate that a combination of multiagent chemotherapy regimen and paclitaxel can prolong the survival time of patients in the stage of the disease or who develop postoperative recurrence.…”