A rare cause of posterior mediastinal masses: extramedullary hematopoiesis (two cases)

Özdemır, Levent; Özdemir, Burcu; Durkaya, Suat; Topal, Cansu; Çalışkan, Sema Nur; Ersoy, Ali Özdemir; Büyükbayram, Gökhan; Özbolat, Zulal

doi:10.5505/respircase.2014.63835

Cited by 2 publications

(4 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…EMH is usually characterized by development of soft tissue masses in the paravertebral area in the thorax. These masses very rarely cause distinct symptoms but may lead to hemothorax and pleural effusion [3]. In our case, the case was asymptomatic and EMH was detected incidentally.…”

Section: Discussionmentioning

confidence: 75%

Intrathoracic extramedullary hematopoiesis as a posterior mediastinal tumor: a case report

Köse

Reyhan

Metin

et al. 2018

The European Research Journal

View full text Add to dashboard Cite

Extramedullary hematopoiesis (EMH) is a rare disorder, defined as the appearance of hematopoietic elements outside the bone marrow or peripheral blood. Usually it is diagnosed incidentally and very rarely it presents as a posterior mediastinal mass clinically mimicking with many other benign or malignant mediastinal tumors. Intrathoracic EMH is a rare condition and only very few case reports have been described in patients with chronic myeloproliferative disorders specially myelofibrosis with myeloid metaplasia and spherocytic anemias. The paravertebral area is an uncommon site for EMH, with the possible exception of sporadically reported intrathoracic manifestations. In this study, a 38-year-old male patient was followed for myeloproliferative disease. Tumor-like lesions at the bilateral posterior mediastinum were detected in the patient who applied to our clinic due to fall. Excision was planned with video-assisted thoracoscopic surgery to differentiate from mediastinal tumors, but the mass unblock was removed with posterolateral thoracotomy because of the appearance of the lesion and large size. Histopathologic diagnosis was reported as extramedullary hematopoiesis. Patient was presented because of its rare location.

show abstract

Section: Discussionmentioning

confidence: 75%

Intrathoracic extramedullary hematopoiesis as a posterior mediastinal tumor: a case report

Köse

Reyhan

Metin

et al. 2018

The European Research Journal

View full text Add to dashboard Cite

show abstract

“…Most of the time, patients are incidentally diagnosed unless there is a symptom associated with the masses [6]. The diagnosis is usually made by the coexistence of a symmetrical, uniformly demarcated, lobulated, homogeneous mass on CT or MRI, and chronic anemia [1,[5][6][7]. When EMH is situated in the posterior mediastinum, it may be confused with other mediastinal masses.…”

Section: Discussionmentioning

confidence: 99%

“…No diagnostic procedure is recommended since the lesion is prone to bleed [1,[4][5][6]. However, VATS is recommended instead of needle biopsy due to effective bleeding control when the diagnosis is uncertain [6].…”

Section: Discussionmentioning

confidence: 99%

“…Extramedullary hematopoiesis (EMH) is defined as the production of blood cells outside the medulla and is normally seen in the liver and spleen during the fetal period [1,2]. On the other hand, EMH also arises in myeloproliferative diseases or hematological diseases, such as hemolytic anemia in adults.However, the mechanism at the molecular level is not fully known [3].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Mass lesion in the neighborhood of the rib and vertebra: extramedullary hematopoiesis

Turan¹,

Demir²,

Önal³

et al. 2019

Curr Thorac Surg

View full text Add to dashboard Cite

Extramedullary hematopoiesis is the production of blood outside of the bone marrow. While it may normally arise in the liver and spleen during the fetal period, it is considered as a compensatory mechanism in adults. Extramedullary hematopoiesis is seen in patients with chronic anemia such as thalassemia, hereditary spherocytosis, most commonly in the liver and spleen, as in the fetal period. On the other hand, intrathoracic hematopoiesis is quite rare. The aim of this study is to discuss this rare condition. A 42-year-old male patient was examined for a mass incidentally detected in the lung during his routine follow-ups. In our patient with no history of diseases except for external thalassemia intermedia, the scattered homogeneous density increments on the posteroanterior chest x-ray were evaluated and his thoracic tomography revealed soft-tissue increments of 7.5 cm in the vicinity of the rib and vertebrae. Extramedullary hematopoiesis should be kept in mind in the differential diagnosis of patients with bilateral masses by the contiguity of the rib and vertebrae. Hematological studies should be conducted in this regard.

show abstract

A rare cause of posterior mediastinal masses: extramedullary hematopoiesis (two cases)

Cited by 2 publications

References 4 publications

Intrathoracic extramedullary hematopoiesis as a posterior mediastinal tumor: a case report

Intrathoracic extramedullary hematopoiesis as a posterior mediastinal tumor: a case report

Mass lesion in the neighborhood of the rib and vertebra: extramedullary hematopoiesis

Contact Info

Product

Resources

About